Search Results - "Lin, Hsiuling"
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Pathological Studies on the Protective Effect of a Macrolide Antibiotic, Roxithromycin, against Sulfur Mustard Inhalation Toxicity in a Rat Model
Published in Toxicologic pathology (01-12-2011)“…Macrolide antibiotics have been shown to protect airway epithelial cells and macrophages from sulfur mustard (SM)–induced cytotoxicity. In the current study,…”
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2
Liver-targeted polymeric prodrugs of 8-aminoquinolines for malaria radical cure
Published in Journal of controlled release (10-03-2021)“…Primaquine and tafenoquine are the two 8-aminoquinoline (8-AQ) antimalarial drugs approved for malarial radical cure - the elimination of liver stage…”
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Toxicogenomic Studies of Human Neural Cells Following Exposure to Organophosphorus Chemical Warfare Nerve Agent VX
Published in Neurochemical research (01-05-2013)“…Organophosphorus (OP) compounds represent an important group of chemical warfare nerve agents that remains a significant and constant military and civilian…”
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Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials
Published in Journal of medicinal chemistry (11-06-2020)“…The global impact of malaria remains staggering despite extensive efforts to eradicate the disease. With increasing drug resistance and the absence of a…”
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Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials
Published in Journal of medicinal chemistry (11-04-2019)“…Malaria remains one of the deadliest diseases in the world today. Novel chemoprophylactic and chemotherapeutic antimalarials are needed to support the renewed…”
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Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure
Published in Science advances (19-04-2024)“…Approximately 3.3 billion people live with the threat of malaria. Infection can result in liver-localized hypnozoites, which when reactivated cause relapsing…”
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