Search Results - "Lin, Hongqiang"
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Comparative Analysis of Chemical Constituents of Moringa oleifera Leaves from China and India by Ultra-Performance Liquid Chromatography Coupled with Quadrupole-Time-Of-Flight Mass Spectrometry
Published in Molecules (Basel, Switzerland) (07-03-2019)“…With the aim to discuss the similarities and differences of phytochemicals in leaves collected from China (CML) and India (IML) in mind, comparative…”
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Effect of ginsenoside Rh 2 on renal apoptosis in cisplatin-induced nephrotoxicity in vivo
Published in Phytomedicine (Stuttgart) (01-08-2019)“…Ginsenoside Rh (Rh ), an important ingredient from Panax ginseng, has received much attention due to a range of pharmacological actions. The aim of the study…”
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UPLC-QTOF/MS-Based Nontargeted Metabolomic Analysis of Mountain- and Garden-Cultivated Ginseng of Different Ages in Northeast China
Published in Molecules (Basel, Switzerland) (21-12-2018)“…Aiming at further systematically comparing the similarities and differences of the chemical components in ginseng of different ages, especially comparing the…”
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Effects of Platycodins Folium on Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics
Published in Molecules (Basel, Switzerland) (02-05-2019)“…Major depressive disorder (MDD), also known as depression, is a state characterized by low mood and aversion to activity. Platycodins Folium (PF) is the dried…”
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Discovery of the Potential Biomarkers for Discrimination between Hedyotis diffusa and Hedyotis corymbosa by UPLC-QTOF/MS Metabolome Analysis
Published in Molecules (Basel, Switzerland) (25-06-2018)“…Willd. (HD) and (L.) Lam. (HC), two closely related species of the same genus, are both used for health benefits and disease prevention in China. HC is also…”
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Pseudoginsengenin DQ Exhibits Therapeutic Effects in Cisplatin-Induced Acute Kidney Injury via Sirt1/NF-κB and Caspase Signaling Pathway without Compromising Its Antitumor Activity in Mice
Published in Molecules (Basel, Switzerland) (21-11-2018)“…In this study, the protective effects of pseudoginsengenin DQ (PDQ) on cisplatin (CDDP)-induced nephrotoxicity were assessed, with a primary investigation into…”
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Protective effect of total Saponins from American ginseng against cigarette smoke-induced COPD in mice based on integrated metabolomics and network pharmacology
Published in Biomedicine & pharmacotherapy (01-05-2022)“…Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disease. Aiming at assessing the effect of total saponins from American ginseng on…”
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Inhibitory Effect of Methotrexate on Rheumatoid Arthritis Inflammation and Comprehensive Metabolomics Analysis Using Ultra-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry (UPLC-Q/TOF-MS)
Published in International journal of molecular sciences (23-09-2018)“…Rheumatoid arthritis (RA) is a common autoimmune disease. The inflammation in joint tissue and system endanger the human health seriously. Methotrexate have…”
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Integrating microbiome and metabolome revealed microbe-metabolism interactions in the stomach of patients with different severity of peptic ulcer disease
Published in Frontiers in immunology (09-03-2023)“…Peptic ulcer disease (PUD) is a multi-cause illness with an unknown role for gastric flora and metabolism in its pathogenesis. In order to further understand…”
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The Role of Metabolomics and Microbiology in Urinary Tract Infection
Published in International journal of molecular sciences (01-03-2024)“…One of the common illnesses that affect women's physical and mental health is urinary tract infection (UTI). The disappointing results of empirical…”
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Non-Targeted Metabolomic Analysis of Methanolic Extracts of Wild-Simulated and Field-Grown American Ginseng
Published in Molecules (Basel, Switzerland) (18-03-2019)“…Aiming at revealing the structural diversity of secondary metabolites and the different patterns in wild-simulated American ginseng (WsAG) and field-grown…”
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Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS
Published in Molecules (Basel, Switzerland) (21-12-2018)“…Pharmacokinetic and metabolism studies were carried out on curculigoside C (CC), a natural product with good antioxidant and neuroprotective effects, with the…”
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The effect of ginsenoside Rg5, isolated from black ginseng, on heart failure in zebrafish based on untargeted metabolomics
Published in Journal of functional foods (01-01-2021)“…[Display omitted] •Ginsenoside Rg5 displayed excellent ACE inhibitory activity in vitro.•Ginsenoside Rg5 exhibited good activity in zebrafish heart failure…”
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Phenotype-Specific Therapeutic Effect of Rhodiola wallichiana var. cholaensis Combined with Dexamethasone on Experimental Murine Asthma and Its Comprehensive Pharmacological Mechanism
Published in International journal of molecular sciences (28-08-2019)“…The heterogeneity of asthma involves complex pathogenesis leading to confusion regarding the choice of therapeutic strategy. In the clinic, asthma is commonly…”
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Pharmacokinetic and Metabolism Studies of 12-Riboside-Pseudoginsengenin DQ by UPLC-MS/MS and UPLC-QTOF-MSE
Published in Molecules (Basel, Switzerland) (29-09-2018)“…Pharmacokinetic and metabolism studies of 12-riboside-pseudoginsengenin DQ (RPDQ), a novel ginsenoside with an anti-cancer effect, were carried out, aiming at…”
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Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats
Published in Journal of ethnopharmacology (30-01-2024)“…Qing-Wei-Zhi-Tong Micro-pills (QWZT) is herbal compound used in the treatment of GU, whose functions include clearing the stomach and fire, softening the liver…”
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Comprehensive Investigation on Metabolites of Wild-Simulated American Ginseng Root Based on Ultra-High-Performance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry
Published in Journal of agricultural and food chemistry (22-05-2019)“…Aiming to evaluate the similarities and differences of the phytochemicals in different morphological regions of wild-simulated American ginseng (WsAG) root,…”
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Elucidation of the mechanism of the Yinhua Miyanling Tablet against urinary tract infection based on a combined strategy of network pharmacology, multi-omics and molecular biology
Published in Journal of ethnopharmacology (30-01-2025)“…Yinhua Miyanling Tablet (YMT), a traditional Chinese medicine consisting of 10 herbs, has been widely used clinically to treat urinary tract infections (UTIs),…”
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Comprehensive investigation on metabolites of Panax quinquefolium L. in two main producing areas of China based on ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry
Published in Journal of mass spectrometry. (01-12-2021)“…Jilin Province and Shandong Province are two main American ginseng (AG) producing areas in China. The geographical difference existed in these two provinces…”
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Comprehensive phytochemical profiling of American ginseng in Jilin province of China based on ultrahigh‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry
Published in Journal of mass spectrometry. (01-11-2021)“…American ginseng (AG), the underground part of Panax quinquefolium L., is composed of four morphological regions, including main root (MR), lateral root (LR),…”
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