Search Results - "Lin, Dongxin"

Association between gut microbiota and preeclampsia-eclampsia: a two-sample Mendelian randomization study by Li, Pengsheng, Wang, Haiyan, Guo, Lan, Gou, Xiaoyan, Chen, Gengdong, Lin, Dongxin, Fan, Dazhi, Guo, Xiaoling, Liu, Zhengping

“…Abstract Background Several recent observational studies have reported that gut microbiota composition is associated with preeclampsia. However, the causal…”
Get full text

Excessive miR-25-3p maturation via N6-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression by Zhang, Jialiang, Bai, Ruihong, Li, Mei, Ye, Huilin, Wu, Chen, Wang, Chengfeng, Li, Shengping, Tan, Liping, Mai, Dongmei, Li, Guolin, Pan, Ling, Zheng, Yanfen, Su, Jiachun, Ye, Ying, Fu, Zhiqiang, Zheng, Shangyou, Zuo, Zhixiang, Liu, Zexian, Zhao, Qi, Che, Xu, Xie, Dan, Jia, Weihua, Zeng, Mu-Sheng, Tan, Wen, Chen, Rufu, Xu, Rui-Hua, Zheng, Jian, Lin, Dongxin

“…N 6 -methyladenosine (m 6 A) modification is an important mechanism in miRNA processing and maturation, but the role of its aberrant regulation in human…”
Get full text

Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis by Zhang, Xiannian, Peng, Linna, Luo, Yingying, Zhang, Shaosen, Pu, Yang, Chen, Yamei, Guo, Wenjia, Yao, Jiacheng, Shao, Mingming, Fan, Wenyi, Cui, Qionghua, Xi, Yiyi, Sun, Yanxia, Niu, Xiangjie, Zhao, Xuan, Chen, Liping, Wang, Yuqian, Liu, Yachen, Yang, Xinyu, Wang, Chengcheng, Zhong, Ce, Tan, Wen, Wang, Jianbin, Wu, Chen, Lin, Dongxin

“…Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal malignant disease, has a complex but unknown tumor ecosystem. Here, we…”
Get full text

Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer by Yao, Jiacheng, Cui, Qionghua, Fan, Wenyi, Ma, Yuling, Chen, Yamei, Liu, Tianyuan, Zhang, Xiannian, Xi, Yiyi, Wang, Chengcheng, Peng, Linna, Luo, Yingying, Lin, Ai, Guo, Wenjia, Lin, Lin, Lin, Yuan, Tan, Wen, Lin, Dongxin, Wu, Chen, Wang, Jianbin

“…Esophageal squamous cell carcinoma (ESCC) is prevalent in some geographical regions of the world. ESCC development presents a multistep pathogenic process from…”
Get full text

Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming by Liu, Jia, Liu, Ze-Xian, Wu, Qi-Nian, Lu, Yun-Xin, Wong, Chau-Wei, Miao, Lei, Wang, Yun, Wang, Zixian, Jin, Ying, He, Ming-Ming, Ren, Chao, Wang, De-Shen, Chen, Dong-Liang, Pu, Heng-Ying, Feng, Lin, Li, Bo, Xie, Dan, Zeng, Mu-Sheng, Huang, Peng, Lin, Aifu, Lin, Dongxin, Xu, Rui-Hua, Ju, Huai-Qiang

“…Tumor cells often reprogram their metabolism for rapid proliferation. The roles of long noncoding RNAs (lncRNAs) in metabolism remodeling and the underlying…”
Get full text

METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma by Li, Ting, Hu, Pei-Shan, Zuo, Zhixiang, Lin, Jin-Fei, Li, Xingyang, Wu, Qi-Nian, Chen, Zhan-Hong, Zeng, Zhao-Lei, Wang, Feng, Zheng, Jian, Chen, Demeng, Li, Bo, Kang, Tie-Bang, Xie, Dan, Lin, Dongxin, Ju, Huai-Qiang, Xu, Rui-Hua

“…Background Colorectal carcinoma (CRC) is one of the most common malignant tumors, and its main cause of death is tumor metastasis. RNA N.sup.6-methyladenosine…”
Get full text

NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization by Su, Jiachun, Wu, Guandi, Ye, Ying, Zhang, Jialiang, Zeng, Lingxing, Huang, Xudong, Zheng, Yanfen, Bai, Ruihong, Zhuang, Lisha, Li, Mei, Pan, Ling, Deng, Junge, Li, Rui, Deng, Shuang, Zhang, Shaoping, Zuo, Zhixiang, Liu, Zexian, Lin, Junzhong, Lin, Dongxin, Zheng, Jian

“…5-Methylcytosine (m 5 C) is a posttranscriptional RNA modification participating in many critical bioprocesses, but its functions in human cancer remain…”
Get full text

A body map of somatic mutagenesis in morphologically normal human tissues by Li, Ruoyan, Di, Lin, Li, Jie, Fan, Wenyi, Liu, Yachen, Guo, Wenjia, Liu, Weiling, Liu, Lu, Li, Qiong, Chen, Liping, Chen, Yamei, Miao, Chuanwang, Liu, Hongjin, Wang, Yuqian, Ma, Yuling, Xu, Deshu, Lin, Dongxin, Huang, Yanyi, Wang, Jianbin, Bai, Fan, Wu, Chen

“…Somatic mutations that accumulate in normal tissues are associated with ageing and disease 1 , 2 . Here we performed a comprehensive genomic analysis of 1,737…”
Get full text

Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction by Lin, Yuan, Luo, Yingying, Sun, Yanxia, Guo, Wenjia, Zhao, Xuan, Xi, Yiyi, Ma, Yuling, Shao, Mingming, Tan, Wen, Gao, Ge, Wu, Chen, Lin, Dongxin

“…Adenocarcinoma at the gastroesophageal junction (ACGEJ) has dismal clinical outcomes, and there are currently few specific effective therapies because of…”
Get full text

LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling by Huang, Xudong, Pan, Ling, Zuo, Zhixiang, Li, Mei, Zeng, Lingxing, Li, Rui, Ye, Ying, Zhang, Jialiang, Wu, Guandi, Bai, Ruihong, Zhuang, Lisha, Wei, Lusheng, Zheng, Yanfen, Su, Jiachun, Deng, Junge, Deng, Shuang, Zhang, Shaoping, Zhu, Shihao, Che, Xu, Wang, Chengfeng, Wu, Chen, Chen, Rufu, Lin, Dongxin, Zheng, Jian

“…The molecular mechanism underlying pancreatic ductal adenocarcinoma (PDAC) malignancy remains unclear. Here, we characterize a long intergenic non-coding RNA…”
Get full text

Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation by Wang, Chengcheng, Zhang, Taiping, Liao, Quan, Dai, Menghua, Guo, Junchao, Yang, Xinyu, Tan, Wen, Lin, Dongxin, Wu, Chen, Zhao, Yupei

“…Pancreatic ductal adenocarcinoma (PDAC) has poor prognosis due to limited therapeutic options. This study examines the roles of genome-wide association study…”
Get full text

PIWI-interacting RNA-36712 restrains breast cancer progression and chemoresistance by interaction with SEPW1 pseudogene SEPW1P RNA by Tan, Liping, Mai, Dongmei, Zhang, Bailin, Jiang, Xiaobing, Zhang, Jialiang, Bai, Ruihong, Ye, Ying, Li, Mei, Pan, Ling, Su, Jiachun, Zheng, Yanfen, Liu, Zexian, Zuo, Zhixiang, Zhao, Qi, Li, Xiaoxing, Huang, Xudong, Yang, Jie, Tan, Wen, Zheng, Jian, Lin, Dongxin

“…Breast cancer is one of the most common malignancies and the major cause of cancer-related death in women. Although the importance of PIWI-interacting RNAs…”
Get full text

Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations by Chang, Jiang, Tan, Wenle, Ling, Zhiqiang, Xi, Ruibin, Shao, Mingming, Chen, Mengjie, Luo, Yingying, Zhao, Yanjie, Liu, Yun, Huang, Xiancong, Xia, Yuchao, Hu, Jinlin, Parker, Joel S., Marron, David, Cui, Qionghua, Peng, Linna, Chu, Jiahui, Li, Hongmin, Du, Zhongli, Han, Yaling, Tan, Wen, Liu, Zhihua, Zhan, Qimin, Li, Yun, Mao, Weimin, Wu, Chen, Lin, Dongxin

“…Approximately half of the world’s 500,000 new oesophageal squamous-cell carcinoma (ESCC) cases each year occur in China. Here, we show whole-genome sequencing…”
Get full text

N6 -methyladenosine–Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression by Deng, Junge, Zhang, Jialiang, Ye, Ying, Liu, Kaijing, Zeng, Lingxing, Huang, Jingyi, Pan, Ling, Li, Mei, Bai, Ruihong, Zhuang, Lisha, Huang, Xudong, Wu, Guandi, Wei, Lusheng, Zheng, Yanfen, Su, Jiachun, Zhang, Shaoping, Chen, Rufu, Lin, Dongxin, Zheng, Jian

“…Abstract Pseudogenes may play important roles in cancer. Here, we explore the mechanism and function of a pseudogene WTAPP1 in the progress of pancreatic…”
Get full text

Identification of genomic alterations in oesophageal squamous cell cancer by Song, Yongmei, Li, Lin, Ou, Yunwei, Gao, Zhibo, Li, Enmin, Li, Xiangchun, Zhang, Weimin, Wang, Jiaqian, Xu, Liyan, Zhou, Yong, Ma, Xiaojuan, Liu, Lingyan, Zhao, Zitong, Huang, Xuanlin, Fan, Jing, Dong, Lijia, Chen, Gang, Ma, Liying, Yang, Jie, Chen, Longyun, He, Minghui, Li, Miao, Zhuang, Xuehan, Huang, Kai, Qiu, Kunlong, Yin, Guangliang, Guo, Guangwu, Feng, Qiang, Chen, Peishan, Wu, Zhiyong, Wu, Jianyi, Ma, Ling, Zhao, Jinyang, Luo, Longhai, Fu, Ming, Xu, Bainan, Chen, Bo, Li, Yingrui, Tong, Tong, Wang, Mingrong, Liu, Zhihua, Lin, Dongxin, Zhang, Xiuqing, Yang, Huanming, Wang, Jun, Zhan, Qimin

“…Using whole-genome and whole-exome sequencing, this study identifies eight significantly mutated genes in oesophageal squamous cell cancer, including two…”
Get full text

Refined expression quantitative trait locus analysis on adenocarcinoma at the gastroesophageal junction reveals susceptibility and prognostic markers by Zhong, Ce, Wu, Chen, Lin, Yuan, Lin, Dongxin

“…This study aimed to explore cell type level expression quantitative trait loci (eQTL) in adenocarcinoma at the gastroesophageal junction (ACGEJ) and identify…”
Get full text

Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations by Dai, Juncheng, Lv, Jun, Zhu, Meng, Wang, Yuzhuo, Qin, Na, Ma, Hongxia, He, Yong-Qiao, Zhang, Ruoxin, Tan, Wen, Fan, Jingyi, Wang, Tianpei, Zheng, Hong, Sun, Qi, Wang, Lijuan, Huang, Mingtao, Ge, Zijun, Yu, Canqing, Guo, Yu, Wang, Tong-Min, Wang, Jie, Xu, Lin, Wu, Weibing, Chen, Liang, Bian, Zheng, Walters, Robin, Millwood, Iona Y, Li, Xi-Zhao, Wang, Xin, Hung, Rayjean J, Christiani, David C, Chen, Haiquan, Wang, Mengyun, Wang, Cheng, Jiang, Yue, Chen, Kexin, Chen, Zhengming, Jin, Guangfu, Wu, Tangchun, Lin, Dongxin, Hu, Zhibin, Amos, Christopher I, Wu, Chen, Wei, Qingyi, Jia, Wei-Hua, Li, Liming, Shen, Hongbing

“…Genetic variation has an important role in the development of non-small-cell lung cancer (NSCLC). However, genetic factors for lung cancer have not been fully…”
Get full text

A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1 by Shi, Yongyong, Hu, Zhibin, Wu, Chen, Dai, Juncheng, Li, Huizhang, Dong, Jing, Wang, Meilin, Miao, Xiaoping, Zhou, Yifeng, Lu, Feng, Zhang, Hanze, Hu, Lingmin, Jiang, Yue, Li, Zhiqiang, Chu, Minjie, Ma, Hongxia, Chen, Jiaping, Jin, Guangfu, Tan, Wen, Wu, Tangchun, Zhang, Zhengdong, Lin, Dongxin, Shen, Hongbing

“…Hongbing Shen, Dongxin Lin, Yongyong Shi and colleagues identify two new susceptibility loci for non-cardia gastric cancer. They also confirm three previously…”
Get full text

Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations by Lin, Dongxin, Wu, Chen, Hu, Zhibin, He, Zhonghu, Jia, Weihua, Wang, Feng, Zhou, Yifeng, Liu, Zhihua, Zhan, Qimin, Liu, Yu, Yu, Dianke, Zhai, Kan, Chang, Jiang, Qiao, Yan, Jin, Guangfu, Liu, Zhe, Shen, Yuanyuan, Guo, Chuanhai, Fu, Jianhua, Miao, Xiaoping, Tan, Wen, Shen, Hongbing, Ke, Yang, Zeng, Yixin, Wu, Tangchun

“…Esophageal squamous-cell carcinoma (ESCC) is one of the most prevalent cancers worldwide and occurs at a relatively high frequency in China. To identify…”
Get full text

Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis by Qin, Hai-De, Liao, Xiao-Yu, Chen, Yuan-Bin, Huang, Shao-Yi, Xue, Wen-Qiong, Li, Fang-Fang, Ge, Xiao-Song, Liu, De-Qing, Cai, Qiuyin, Long, Jirong, Li, Xi-Zhao, Hu, Ye-Zhu, Zhang, Shao-Dan, Zhang, Lan-Jun, Lehrman, Benjamin, Scott, Alan F., Lin, Dongxin, Zeng, Yi-Xin, Shugart, Yin Yao, Jia, Wei-Hua

“…The genetic mechanisms underlying the poor prognosis of esophageal squamous cell carcinoma (ESCC) are not well understood. Here, we report somatic mutations…”
Get full text