Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress

Autophagy is a highly conserved process of degradation of cytoplasmic constituents in eukaryotes. It is involved in the growth and development of plants, as well as in biotic and abiotic stress response. Although autophagy-related (ATG) genes have been identified and characterized in many plant spec...

Full description

Saved in:

Bibliographic Details
Published in:	Scientific reports Vol. 11; no. 1; p. 22933
Main Authors:	Yang, Mingkang, Wang, Liping, Chen, Chumin, Guo, Xu, Lin, Chuanglie, Huang, Wei, Chen, Liang
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 25-11-2021 Nature Publishing Group Nature Portfolio
Subjects:	631/449/2491 631/449/2661 Alfalfa Autophagy Autophagy - genetics Autophagy-Related Proteins - genetics Autophagy-Related Proteins - metabolism Drought Droughts Evolution, Molecular Gene Expression Regulation, Plant Gene Regulatory Networks Genes, Plant Genome, Plant Genome-Wide Association Study Genomes Humanities and Social Sciences Medicago truncatula Medicago truncatula - genetics Medicago truncatula - growth & development Medicago truncatula - metabolism multidisciplinary Phagocytosis Phylogeny Plant Proteins - genetics Plant Proteins - metabolism Plant species Protein Interaction Maps Science Science (multidisciplinary) Seeds Seeds - genetics Seeds - growth & development Seeds - metabolism Signal Transduction Stress, Physiological - genetics
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Autophagy is a highly conserved process of degradation of cytoplasmic constituents in eukaryotes. It is involved in the growth and development of plants, as well as in biotic and abiotic stress response. Although autophagy-related (ATG) genes have been identified and characterized in many plant species, little is known about this process in Medicago truncatula . In this study, 39 ATGs were identified, and their gene structures and conserved domains were systematically characterized in M. truncatula . Many cis-elements, related to hormone and stress responsiveness, were identified in the promoters of MtATGs . Phylogenetic and interaction network analyses suggested that the function of Mt ATGs is evolutionarily conserved in Arabidopsis and M. truncatula . The expression of MtATGs , at varied levels, was detected in all examined tissues. In addition, most of the MtATGs were highly induced during seed development and drought stress, which indicates that autophagy plays an important role in seed development and responses to drought stress in M. truncatula . In conclusion, this study gives a comprehensive overview of MtATGs and provides important clues for further functional analysis of autophagy in M. truncatula .
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-021-02239-6