Search Results - "Lin, Binyan"

Flavonoid VI-16 protects against DSS-induced colitis by inhibiting Txnip-dependent NLRP3 inflammasome activation in macrophages via reducing oxidative stress by Zhao, Yue, Guo, Qinglong, Zhu, Qin, Tan, Renxiang, Bai, Dongsheng, Bu, Xiumin, Lin, Binyan, Zhao, Kai, Pan, Chuyue, Chen, Haiyan, Lu, Na

“…Emerging evidence suggests that NLRP3 inflammasome was associated with various kinds of immunological diseases including colitis. However, there are few drugs…”
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CRMP2 is a therapeutic target that suppresses the aggressiveness of breast cancer cells by stabilizing RECK by Lin, Binyan, Li, Yongxu, Wang, Tiepeng, Qiu, Yangmin, Chen, Zhenzhong, Zhao, Kai, Lu, Na

“…Metastatic breast cancer is characterized by high mortality and limited therapeutic target. During tumor metastasis, cytoskeletal reorganization is one of the…”
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Heat Shock-induced Phosphorylation of TAR DNA-binding Protein 43 (TDP-43) by MAPK/ERK Kinase Regulates TDP-43 Function by Li, Wen, Reeb, Ashley N., Lin, Binyan, Subramanian, Praveen, Fey, Erin E., Knoverek, Catherine R., French, Rachel L., Bigio, Eileen H., Ayala, Yuna M.

“…TAR DNA-binding protein (TDP-43) is a highly conserved and essential DNA- and RNA-binding protein that controls gene expression through RNA processing, in…”
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Baitouweng decoction alleviates ulcerative colitis by regulating tryptophan metabolism through DOPA decarboxylase promotion by Zhang, Junzhi, Lin, Binyan, Zhang, Ying, Hu, Xiaochao, Liu, Tongtong, Liu, E-Hu, Liu, Shijia

“…Baitouweng decoction (BTW) is a classic botanical drugs formula that has been widely used clinically for the treatment of gut-related disorders in China…”
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Ring Transformation of Cyclopropenes to Benzo‐Fused Five‐Membered Oxa‐ and Aza‐Heterocycles via a Formal [4+1] Cyclization by Gu, Fengyan, Lin, Binyan, Peng, Zhi‐Huan, Liu, Shijie, Wu, Yuanqing, Luo, Mei, Ding, Ning, Zhan, Qichen, Cao, Peng, Zhou, Zhi, Cao, Tao

“…In the context of the growing importance of heterocyclic compounds across various disciplines, numerous strategies for their construction have emerged…”
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Anlotinib inhibits angiogenesis via suppressing the activation of VEGFR2, PDGFRβ and FGFR1 by Lin, Binyan, Song, Xiuming, Yang, Dawei, Bai, Dongsheng, Yao, Yuyuan, Lu, Na

“…Tumor cells recruit vascular endothelial cells and circulating endothelial progenitor cells to form new vessels to support their own growth and metastasis…”
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Gambogic acid impairs the maintenance and therapeutic resistance of glioma stem cells by targeting B-cell-specific Moloney leukemia virus insert site 1 by Sun, Tifan, Lin, Binyan, Sun, Qiruo, Zhang, Xueyan, Wang, Tiepeng, Yang, Jinming, Liu, Xinye, Lu, Hong, Lu, Na, Zhao, Kai

“…•GA is a specific inhibitor of BMI1 in glioma stem cells.•GA targets BMI1 to impair GSC maintenance & resistance.•GA is a potential candidate for targeting…”
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LW-215, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo by Zhao, Kai, Yuan, Yang, Lin, Binyan, Miao, Zhaorui, Li, Zhiyu, Guo, Qinglong, Lu, Na

“…LW-215 is a newly synthesized flavonoid, which is the derivative of wogonin. Our group has previously confirmed that wogonin has an anti-angiogenic activity,…”
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Fucoxanthin triggers ferroptosis in glioblastoma cells by stabilizing the transferrin receptor by Zhu, Qin, Zhou, Yanqing, Wang, Haixia, Cao, Tao, Wang, Xinzhi, Liu, Rui, Wu, Hao, Lin, Binyan

“…Glioblastoma (GBM) is the most common and lethal tumor in the world, possessing high stemness, aggressiveness and resistance. Fucoxanthin is a bio-active…”
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Oroxyloside inhibits angiogenesis through suppressing internalization of VEGFR2/Flk‐1 in endothelial cells by Zhao, Kai, Li, Xiaorui, Lin, Binyan, Yang, Dawei, Zhou, Yuxin, Li, Zhiyu, Guo, Qinglong, Lu, Na

“…Increasing flavonoids have been reported to possess anti‐angiogenic effects. Inhibition of angiogenesis plays a critical role in the treatment of cancer,…”
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LYG-202 inhibits activation of endothelial cells and angiogenesis through CXCL12/CXCR7 pathway in breast cancer by Zhao, Kai, Yao, Yuyuan, Luo, Xuwei, Lin, Binyan, Huang, Yujie, Zhou, Yuxin, Li, Zhiyu, Guo, Qinglong, Lu, Na

“…Abstract Angiogenesis is critical for the growth and metastasis of triple-negative breast cancer (TNBC) and its inhibition reduces the risk of progression of…”
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NQO1 Triggers Neutrophil Recruitment and NET formation to Drive Lung Metastasis of Invasive Breast Cancer by Wang, Xinzhi, Qu, Yi, Xu, Qianqian, Jiang, Zeyu, Wang, Hang, Lin, Binyan, Cao, Zehong, Pan, Yuqi, Li, Sheng, Hu, Yili, Yang, Hui, He, Li, Chang, Hang, Hang, Bo, Wen, Hongmei, Wu, Hao, Mao, Jian-Hua

“…Metastasis to the lungs is a leading cause of death for breast cancer patients. Therefore, effective therapies are urgently needed to prevent and treat breast…”
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Corrigendum to “Anlotinib inhibits angiogenesis via suppressing the activation of VEGFR2, PDGFRβ and FGFR1” [Gene 654 (2018) 77–86] by Binyan, Lin, Xiuming, Song, Dawei, Yang, Dongsheng, Bai, Yuyuan, Yao, Na, Lu

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Wogonoside impedes the progression of acute myeloid leukemia through inhibiting bone marrow angiogenesis by Lin, Binyan, Zhao, Kai, Yang, Dawei, Bai, Dongsheng, Liao, Yan, Zhou, Yuxin, Yu, Zhou, Yu, Xiaoxuan, Guo, Qinglong, Lu, Na

“…Decreasing bone marrow (BM) microvessel density and circulating angiogenic cytokine levels are promising strategies for the treatment of relapsed and resistant…”
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Ring Transformation of Cyclopropenes to Benzo-Fused Five-Membered Oxa- and Aza-Heterocycles via a Formal 4+1 Cyclization by Gu, Fengyan, Lin, Binyan, Peng, Zhi-Huan, Liu, Shijie, Wu, Yuanqing, Luo, Mei, Ding, Ning, Zhan, Qichen, Cao, Peng, Zhou, Zhi, Cao, Tao

“…In the context of the growing importance of heterocyclic compounds across various disciplines, numerous strategies for their construction have emerged…”
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A Parameter Estimation of Fractional Order Grey Model Based on Adaptive Dynamic Cat Swarm Algorithm by Lin, Binyan, Gao, Fei, Wang, Meng, Xiong, Yuyao, Li, Ansheng

“…In this paper, we utilize ADCSO (Adaptive Dynamic Cat Swarm Optimization) to estimate the parameters of Fractional Order Grey Model. The parameters of…”
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