Search Results - "Lin, Aimee B"

Dose‐finding study of the checkpoint kinase 1 inhibitor, prexasertib, in Japanese patients with advanced solid tumors by Iwasa, Satoru, Yamamoto, Noboru, Shitara, Kohei, Tamura, Kenji, Matsubara, Nobuaki, Tajimi, Masaomi, Lin, Aimee B., Asou, Hiroya, Cai, Zhihong, Inoue, Koichi, Shibasaki, Yuko, Saito, Kanako, Takai, Hiroki, Doi, Toshihiko

“…Prexasertib is a novel inhibitor of checkpoint kinase 1. The primary objective of this study was to evaluate prexasertib tolerability in Japanese patients with…”
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A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models by Yin, Tinggui, Lallena, Maria J, Kreklau, Emiko L, Fales, Kevin R, Carballares, Santiago, Torrres, Raquel, Wishart, Graham N, Ajamie, Rose T, Cronier, Damien M, Iversen, Phillip W, Meier, Timothy I, Foreman, Robert T, Zeckner, Douglas, Sissons, Sean E, Halstead, Bart W, Lin, Aimee B, Donoho, Gregory P, Qian, Yuewei, Li, Shuyu, Wu, Song, Aggarwal, Amit, Ye, Xiang S, Starling, James J, Gaynor, Richard B, de Dios, Alfonso, Du, Jian

“…DNA-dependent RNA polymerase II (RNAP II) largest subunit RPB1 C-terminal domain (CTD) kinases, including CDK9, are serine/threonine kinases known to regulate…”
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