Search Results - "Limper, Candice"
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Past, Present, and Future of Rituximab-The World's First Oncology Monoclonal Antibody Therapy
Published in Frontiers in oncology (04-06-2018)“…Rituximab is a chimeric mouse/human monoclonal antibody (mAb) therapy with binding specificity to CD20. It was the first therapeutic antibody approved for…”
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Effective differentiation of double negative thymocytes requires high fidelity replication of mitochondrial DNA in an age dependent manner
Published in Frontiers in immunology (20-03-2023)“…One of the most proliferative periods for T cells occurs during their development in the thymus. Increased DNA replication can result in increased DNA…”
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Interleukin-2-Inducible T-Cell Kinase Deficiency Impairs Early Pulmonary Protection Against Mycobacterium tuberculosis Infection
Published in Frontiers in immunology (24-01-2020)“…Interleukin-2 (IL-2) inducible T-cell kinase (ITK) is a non-receptor tyrosine kinase highly expressed in T-cell lineages and regulates multiple aspects of…”
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Brief Research Report: Veterinary Student Perspective on COVID-19 and Veterinary Medicine
Published in Frontiers in veterinary science (14-10-2021)“…COVID-19 has had significant effects on the field of veterinary medicine. Adaptation to pandemic-related and post-pandemic challenges requires engagement from…”
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TCR Signal Strength and Antigen Affinity Regulate CD8 + Memory T Cells
Published in The Journal of immunology (1950) (01-09-2020)“…CD8 T cells play a critical role in adaptive immunity, differentiating into CD8 memory T cells that form the basis of protective cellular immunity. Vaccine…”
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Effect of Perfluorooctanesulfonic acid (PFOS) on immune cell development and function in mice
Published in Immunology letters (01-05-2021)“…•Perfluoroctanesulfonate (PFOS), a larger family of compounds known as Per and polyfluoroalkyl substances (PFAS), have high persistence.•Previous work suggests…”
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ITK signaling regulates IL-10 production by CD8+ T cells and lung immunopathology during influenza infection
Published in The Journal of immunology (1950) (01-05-2022)“…Influenza (flu) infections cause 250,000 deaths and 3–5 million cases of severe illness during the average flu season. Severe influenza infections are…”
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Effects of PFOS and cyclophosphamide exposure on immune homeostasis in mice
Published in Immunobiology (1979) (01-05-2023)“…Perfluorooctane sulfonic acid (PFOS) is member of a class of molecules with fluorinated carbon chains known as polyfluoroalkyls. PFOS have been used to produce…”
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Development of regulatory IL-10-producing ILCs during type 2 inflammation
Published in The Journal of immunology (1950) (01-05-2020)“…Innate lymphoid cells (ILCs) are important for mucosal homeostasis and host defense against infectious pathogens. ILC subsets ILC1, 2, and 3, classified…”
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Heterogeneity of regulatory T cells during lung inflammation
Published in The Journal of immunology (1950) (01-05-2020)“…Pulmonary inflammation is the leading cause of respiratory illness worldwide. Although strong T cell responses are desired for defending the hosts against…”
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ITK regulates IL-10 production by CD8+ T cells and lung immunopathology during influenza infection
Published in The Journal of immunology (1950) (01-05-2020)“…Influenza (flu) infections cause 250,000 deaths and 3–5 million cases of severe illness during the average flu season. Severe influenza infections are…”
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12
ITK regulates IL-10 production by CD8+ T cells and lung immunopathology during influenza infection
Published in The Journal of immunology (1950) (01-05-2021)“…Respiratory viral infections are a major cause of human morbidity and mortality. Influenza (flu) infections cause 250,000 deaths and 3–5 million cases of…”
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