Search Results - "Limonta Fernández, Miladys"

Cuban Abdala vaccine: Effectiveness in preventing severe disease and death from COVID-19 in Havana, Cuba; A cohort study by Más-Bermejo, Pedro I., Dickinson-Meneses, Félix O., Almenares-Rodríguez, Kenia, Sánchez-Valdés, Lizet, Guinovart-Díaz, Raúl, Vidal-Ledo, María, Galbán-García, Enrique, Olivera-Nodarse, Yadira, Morgado-Vega, Isabel, Dueñas-Carrera, Santiago, Pujol, Merardo, Hernández-Bernal, Francisco, Limonta-Fernández, Miladys, Guillén-Nieto, Gerardo, Muzio-González, Verena L., Ayala-Ávila, Marta

“…COVID-19 vaccines have proven safe and efficacious in reducing severe illness and death. Cuban protein subunit vaccine Abdala has shown safety, tolerability…”
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Evaluation of methodologies to determine the effect of specific active immunotherapy on VEGF levels in phase I clinical trial patients with advanced solid tumors by Sánchez Ramírez, Javier, Bequet-Romero, Mónica, Morera Díaz, Yanelys, Hernández-Bernal, Francisco, de la Torre Santos, Ana, Selman-Housein Bernal, Katty-Hind, Martín Bauta, Yenima, Bermúdez Badell, Cimara H., Limonta Fernández, Miladys, Ayala Avila, Marta

“…Two phase I clinical trials were conducted to evaluate, among other parameters, the humoral response elicited by a vascular endothelial growth factor…”
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An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen by Limonta-Fernández, Miladys, Chinea-Santiago, Glay, Martín-Dunn, Alejandro Miguel, Gonzalez-Roche, Diamile, Bequet-Romero, Monica, Marquez-Perera, Gabriel, González-Moya, Isabel, Canaan-Haden-Ayala, Camila, Cabrales-Rico, Ania, Espinosa-Rodríguez, Luis Ariel, Ramos-Gómez, Yassel, Andujar-Martínez, Ivan, González-López, Luis Javier, de la Iglesia, Mariela Perez, Zamora-Sanchez, Jesus, Cruz-Sui, Otto, Lemos-Pérez, Gilda, Cabrera-Herrera, Gleysin, Valdes-Hernández, Jorge, Martinez-Diaz, Eduardo, Pimentel-Vazquez, Eulogio, Ayala-Avila, Marta, Guillén-Nieto, Gerardo

“…Developing affordable and easily manufactured SARS-CoV-2 vaccines will be essential to achieve worldwide vaccine coverage and long-term control of the COVID-19…”
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Safety and Immunogenicity of the Intranasal Vaccine Candidate Mambisa and the Intramuscular Vaccine Abdala Used as Booster Doses for COVID-19 Convalescents: A Randomized Phase 1-2 Clinical Trial by Lemos-Pérez, Gilda, Barrese-Pérez, Yinet, Chacón-Quintero, Yahima, Uranga-Piña, Rolando, Avila-Albuerne, Yisel, Figueroa-García, Iglermis, Calderín-Marín, Osaida, Gómez-Vázquez, Martha M, Piñera-Martínez, Marjoris, Chávez-Valdés, Sheila, Martínez-Rosales, Ricardo, Ávila-Díaz, Lismary, Vázquez-Arteaga, Amalia, González-Formental, Hany, Freyre-Corrales, Giselle, Coizeau-Rodríguez, Edelgis, Limonta-Fernández, Miladys, Ayala-Avila, Marta, Martínez-Díaz, Eduardo, Pimentel-Vazquez, Eulogio, Guillen, Gerardo

“…A phase 1-2, prospective, multicenter, randomized, open-label clinical trial (Code RPCEC00000382), with parallel groups, involving 1161 participants, was…”
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Correction to “Cuban Abdala vaccine: Effectiveness in preventing severe disease and death from COVID-19 in Havana, Cuba; A cohort study” [The Lancet Regional Health – Americas 2022; 16: 100366] https://doi.org/10.1016/j.lana.2022.100366 by Más-Bermejo, Pedro I., Dickinson-Meneses, Félix O., Almenares-Rodríguez, Kenia, Sánchez-Valdés, Lizet, Guinovart-Díaz, Raúl, Vidal-Ledo, María, Galbán-García, Enrique, Olivera-Nodarse, Yadira, Morgado-Vega, Isabel, Dueñas-Carrera, Santiago, Pujol, Merardo, Hernández-Bernal, Francisco, Limonta-Fernández, Miladys, Guillén-Nieto, Gerardo, Muzio-González, Verena L., Ayala-Ávila, Marta

“…[This corrects the article DOI: 10.1016/j.lana.2022.100366.]…”
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Nuevas contribuciones al estudio de los efectores inmunológicos inducidos con la inmunoterapia activa específica CIGB-247 by Javier Sánchez Ramírez, Yanelys Morera Díaz, Mónica Bequet Romero, Francisco Hernández Bernal, Marta Ayala Ávila, Jorge V. Gavilondo Cowley, Yenima Martin Bauta, Katty-Hind Selman-Housein Bernal, Ana Victoria de la Torre Santos, Mariela Pérez de la Iglesia, Lian Trimiño Lorenzo, Miladys Limonta Fernández

“…Objetivos. Esta investigación tiene como objetivo estudiar los efectores inmunológicos que se inducen en los pacientes inmunizados con el CIGB-247, que…”
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Efficacy and safety of Abdala COVID-19 subunit vaccine in children and adolescents: An open-label, single-arm, phase 2 trial (MEÑIQUE) by Hernández-Bernal, Francisco, Noa-Romero, Enrique, Quintana-Guerra, Joel, Chávez-Chong, Cristina O., Martín-Bauta, Yenima, Alvaré-Alvaré, Laura, Salvato-Dueñas, Alena, Felipe-Mallea, Danusia, Porta-Díaz, Mairalys, Cruz-Sui, Otto, Urrutia-Pérez, Karen, Urrutia-Pérez, Klaudia, Rodríguez-Reinoso, José L., Alonso-Valdés, Marel, Cinza-Estévez, Zurina, Rodríguez-Triana, Aylin, Cruz-Gómez, Yolanda, Limonta-Fernández, Miladys, Rodríguez-Acosta, Mireida, Ayala-Ávila, Marta, Muzio-González, Verena L.

“…Objectives We evaluated the safety, immunogenicity and efficacy of Abdala, a protein subunit vaccine for 2019 coronavirus disease (COVID-19), in children and…”
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Safety, tolerability, and immunogenicity of a SARS-CoV-2 recombinant spike RBD protein vaccine: A randomised, double-blind, placebo-controlled, phase 1-2 clinical trial (ABDALA Study) by Hernández-Bernal, Francisco, Ricardo-Cobas, Maria C., Martín-Bauta, Yenima, Navarro-Rodríguez, Zadis, Piñera-Martínez, Marjoris, Quintana-Guerra, Joel, Urrutia-Pérez, Karen, Urrutia-Pérez, Klaudia, Chávez-Chong, Cristina O., Azor-Hernández, Jorge L., Rodríguez-Reinoso, José L., Lobaina-Lambert, Leonardo, Colina-Ávila, Elizabeth, Bizet-Almeida, Jacqueline, Rodríguez-Nuviola, Jeniffer, del Valle-Piñera, Sergio, Ramírez-Domínguez, Mayara, Tablada-Ferreiro, Elisangela, Alonso-Valdés, Marel, Lemos-Pérez, Gilda, Guillén-Nieto, Gerardo E., Palenzuela-Díaz, Ariel, Noa-Romero, Enrique, Limonta-Fernández, Miladys, Fernández-Ávila, Juan M., Ali-Mros, Nabil A., del Toro-Lahera, Lianne, Remedios-Reyes, Rossana, Ayala-Ávila, Marta, Muzio-González, Verena L.

“…Multiple vaccine candidates against COVID-19 are currently being evaluated. We evaluate the safety and immunogenicity protein of a novel SARS-CoV-2 virus…”
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A phase 3, randomised, double-blind, placebo-controlled clinical trial evaluation of the efficacy and safety of a SARS-CoV-2 recombinant spike RBD protein vaccine in adults (ABDALA-3 study) by Hernández-Bernal, Francisco, Ricardo-Cobas, Maria C., Martín-Bauta, Yenima, Rodríguez-Martínez, Ernesto, Urrutia-Pérez, Klaudia, Urrutia-Pérez, Karen, Quintana-Guerra, Joel, Navarro-Rodríguez, Zadis, Piñera-Martínez, Marjoris, Rodríguez-Reinoso, José L., Chávez-Chong, Cristina O., Baladrón-Castrillo, Idania, Melo-Suárez, Grettel, Batista-Izquierdo, Alejandro, Pupo-Micó, Alexis, Mora-Betancourt, Ricardo, Bizet-Almeida, Jacqueline, Martínez-Rodríguez, Maria C., Lobaina-Lambert, Leonardo, Velázquez-Pérez, Vivian M., Soler-Díaz, Jalimy, Laurencio-Vallina, Sandra, Meriño-Hechavarría, Tamara, Carmenaty-Campos, Norberto, Rodríguez-Montero, Enri, Limonta-Fernández, Miladys, Alonso-Valdés, Marel, Hernández-Rodríguez, Reinier, Pimentel-Vázquez, Eulogio, Catasús-Álvarez, Karem M., Cabrera-Núñez, Maria V., Ayala-Ávila, Marta, Muzio-González, Verena L., Hernández-Bernal, Francisco, Ricardo-Cobas, Maria C., Martín-Bauta, Yenima, Rodríguez-Martínez, Ernesto, Urrutia-Pérez, Klaudia, Urrutia-Pérez, Karen, Quintana-Guerra, Joel, Navarro-Rodríguez, Zadis, Piñera-Martínez, Marjoris, Rodríguez-Reinoso, José L., Chávez-Chong, Cristina O., Baladrón-Castrillo, Idania, Melo-Suárez, Grettel, Batista-Izquierdo, Alejandro, Pupo-Micó, Alexis, Mora-Betancourt, Ricardo, Bizet-Almeida, Jacqueline, Martínez-Rodríguez, Maria C., Lobaina-Lambert, Leonardo, Velázquez-Pérez, Vivian M., Soler-Díaz, Jalimy, Laurencio-Vallina, Sandra, Meriño-Hechavarría, Tamara, Carmenaty-Campos, Norberto, Rodríguez-Montero, Enri, Limonta-Fernández, Miladys, Alonso-Valdés, Marel, Hernández-Rodríguez, Reinier, Pimentel-Vázquez, Eulogio, Catasús-Álvarez, Karem M., Cabrera-Núñez, Maria V., Ayala-Ávila, Marta, Muzio-González, Verena L.

“…The pandemic of COVID-19 raised the urgent need for safe and efficacious vaccines against SARS-CoV-2. We evaluated the efficacy and safety of a new SARS-CoV-2…”
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Epidermal Growth Factor Intralesional Delivery in Chronic Wounds: The Pioneer and Standalone Technique for Reversing Wound Chronicity and Promoting Sustainable Healing by Berlanga-Acosta, Jorge, Garcia-Ojalvo, Ariana, Fernández-Montequin, Jose, Falcon-Cama, Viviana, Acosta-Rivero, Nelson, Guillen-Nieto, Gerardo, Pujol-Ferrer, Merardo, Limonta-Fernandez, Miladys, Ayala-Avila, Marta, Eriksson, Elof

“…The early expectations about growth factors' (GFs') discovery as an undisputed therapeutic solution for chronic wounds progressively eclipsed when they failed…”
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Effect of the Selection Marker on the Viability and Plasmid Stability of Two Human Proteins with Neurotrophic Action Expressed inEscherichia coli by Marı́, Yssel Mendoza, Espinosa, Angela Estela Sosa, Ubieta, Raimundo, Batista, Osmani Fernández, Fernández, Miladys Limonta

“…Most developed expression systems rely on the production of fusion proteins or the change of selection marker increasing genetic stability to avoid toxicity of…”
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Effect of the selection marker on the viability and plasmid stability of two human proteins with neurotrophic action expressed in Escherichia coli by Marí, Y M, Espinosa, A E, Ubieta, R, Batista, O F, Fernández, M L

“…Most developed expression systems rely on the production of fusion proteins or the change of selection marker increasing genetic stability to avoid toxicity of…”
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Scale up of fed-batch culture to produce plasmid DNA in Escherichia coli by Hernandez, Odalys Ruiz, Hernandez, Jorge Valdes, Planche, Willy Frometa, Martinez, Michel Diaz, Almihaque, Daniel Alvares, Pena, Marta Pupo, Fernandez, Miladys Limonta, Idahody, Dinorah Torres, Martinez, Eduardo

“…Scale-up from a 5-L fermentor to a 50-L pilot-scale fermentor was carried out successfully using the criterion of constant power consumption per unit liquid…”
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High-cell-density culture to produce plasmid DNA for gene therapy in E. coli by Hernandez, Odalys Ruiz, de la Iglesia, Mariela Perez, Pena, Marta Pupo, Fernandez, Miladys Limonta, Idahody, Dinorah Torres, Gomez, Saily Martinez, Cosme, Arelia Macias, Martinez, Michel Diaz, Jimenez, Yanay Proenza, Hernandez, Jorge Valdes, Diaz, Eduardo Martinez

“…The recombinant host Escherichia coli DH10B bearing the plasmid pIDKE2 was grown under fed batch conditions, and the effects of different medium components on…”
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Design of the purification process by metal-chelate affinity chromatography of a new vaccine antigen for the control of sea lice by Carlos E Perez-Heredia, Nemecio González-Fernández, Licette León-Barreras, Eladio Salazar-Gomez, Rafael Pimentel-Pérez, Eulogio Pimentel-Vázquez, Carmen García-Molina, Yamila Carpio-González, Mario P Estrada-García, Miladys Limonta-Fernández

“…The present work aims at designing the purification process of protein MY32/Ls to obtain the active pharmaceutical ingredient (API) against sea lice, marine…”
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