Search Results - "Limesand, K. H."

Sensitivity of Salivary Glands to Radiation: from Animal Models to Therapies by Grundmann, O., Mitchell, G.C., Limesand, K.H.

“…Radiation therapy for head and neck cancer causes significant secondary side-effects in normal salivary glands, resulting in diminished quality of life for…”
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Chronic Phenotypes Underlying Radiation-Induced Salivary Gland Dysfunction by Gunning, J.A., Limesand, K.H.

“…Head and neck cancer (HNC) is the sixth most diagnosed cancer, and treatment typically consists of surgical removal of the tumor followed by ionizing radiation…”
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AMPK Activation Restores Salivary Function Following Radiation Treatment by Meyer, R.K., Gilman, K.E., Rheinheimer, B.A., Meeks, L., Limesand, K.H.

“…Head and neck cancers represent a significant portion of cancer diagnoses, with head and neck cancer incidence increasing in some parts of the world. Typical…”
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Insulin-Like Growth Factor-1–Mediated DNA Repair in Irradiated Salivary Glands Is Sirtuin-1 Dependent by Meyer, S., Chibly, A.M., Burd, R., Limesand, K.H.

“…Ionizing radiation is one of the most common cancer treatments; however, the treatment leads to a wide range of debilitating side effects. In patients with…”
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The Role of Autophagy in Salivary Gland Homeostasis and Stress Responses by Morgan-Bathke, M., Lin, H.H., Ann, D.K., Limesand, K.H.

“…Autophagy is a catabolic process that has been shown to have a role in many cellular processes including the removal of excessive or damaged proteins and…”
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Dynamic involvement of ATG5 in cellular stress responses by Lin, H H, Lin, S-M, Chung, Y, Vonderfecht, S, Camden, J M, Flodby, P, Borok, Z, Limesand, K H, Mizushima, N, Ann, D K

“…Autophagy maintains cell and tissue homeostasis through catabolic degradation. To better delineate the in vivo function for autophagy in adaptive responses to…”
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Head and Neck Tumor Cell Radiation Response Occurs in the Presence of IGF1 by Victory, K., Burd, R., Fribley, A., Sittadjody, S., Arnett, D., Klein, R.R., Limesand, K.H.

“…Radiation therapy for head and neck cancer results in severe secondary side-effects in salivary glands. We previously demonstrated that the administration of…”
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Deletion of ATG5 Shows a Role of Autophagy in Salivary Homeostatic Control by Morgan-Bathke, M., Lin, H.H., Chibly, A.M., Zhang, W., Sun, X., Chen, C.-H., Flodby, P., Borok, Z., Wu, R., Arnett, D., Klein, R.R., Ann, D.K., Limesand, K.H.

“…Autophagy is a catabolic pathway utilized to maintain a balance among the synthesis, degradation, and recycling of cellular components, thereby playing a role…”
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Critical Review in Oral Biology & Medicine: Sensitivity of Salivary Glands to Radiation: from Animal Models to Therapies by Grundmann, O, Mitchell, GC, Limesand, KH

“…Radiation therapy for head and neck cancer causes significant secondary side-effects in normal salivary glands, resulting in diminished quality of life for…”
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Effect of Mosquito Salivary Gland Treatment on Vesicular Stomatitis New Jersey Virus Replication and Interferon α/β Expression In Vitro by Limesand, K. H., Higgs, S., Pearson, L. D., Beaty, B. J.

“…The sensitivity of vesicular stomatitis (VS) viruses to interferon (IFN)-mediated anti-viral effects has been well documented. Previous studies in our…”
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Potentiation of vesicular stomatitis New Jersey virus infection in mice by mosquito saliva by Limesand, K H, Higgs, S, Pearson, L D, Beaty, B J

“…Saliva of arthropod vectors can modulate vertebrate host immunological functions in many ways. To investigate if vesicular stomatitis New Jersey virus (VSNJ)…”
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Synergistic suppression of apoptosis in salivary acinar cells by IGF1 and EGF by Limesand, K H, Barzen, K A, Quissell, D O, Anderson, S M

“…Tissue homeostasis requires balancing cell proliferation and programmed cell death. IGF1 significantly suppressed etoposide-induced apoptosis, measured by…”
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IGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoter by Mitchell, G C, Fillinger, J L, Sittadjody, S, Avila, J L, Burd, R, Limesand, K H

“…Radiotherapy for head and neck tumors often results in persistent loss of function in salivary glands. Patients suffering from impaired salivary function…”
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Suppression of Apoptosis in the Protein Kinase Cδ Null Mouse in Vivo by Humphries, Michael J., Limesand, Kirsten H., Schneider, Jonathan C., Nakayama, Keiichi I., Anderson, Steven M., Reyland, Mary E.

“…Protein kinase C (PKC) δ is an essential regulator of mitochondrial dependent apoptosis in epithelial cells. We have used the PKCδ-/- mouse to ask if loss of…”
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IGF1 activates cell cycle arrest following irradiation by reducing binding of [Delta]Np63 to the p21 promoter by Mitchell, G C, Fillinger, J L, Sittadjody, S, Avila, J L, Burd, R, Limesand, K H

“…Radiotherapy for head and neck tumors often results in persistent loss of function in salivary glands. Patients suffering from impaired salivary function…”
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Effect of Mosquito Salivary Gland Treatment on Vesicular Stomatitis New Jersey Virus Replication and Interferon alpha / beta Expression In Vitro by Limesand, KH, Higgs, S, Pearson, L D, Beaty, B J

“…The sensitivity of vesicular stomatitis (VS) viruses to interferon (IFN)-mediated anti-viral effects has been well documented. Previous studies in our…”
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CHARACTERIZATION OF RAT PAROTID AND SUBMANDIBULAR ACINAR CELL APOPTOSIS IN PRIMARY CULTURE by LIMESAND, KIRSTEN H, BARZEN, KATHERINE A, SANDERS, LINDA A, SCLAFANI, ROBERT A, RAYNOLDS, MARY V, REYLAND, MARY E, ANDERSON, STEVEN M, QUISSELL, DAVID O

“…Apoptosis is a highly organized cellular process that is critical for maintaining glandular homeostasis. We have used primary rat salivary acinar cells from…”
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Characterization Of Rat Parotid And Submandibular Acinar Cell Apoptosis In Primary Culture by Limesand, KH, Barzen, KA, Sanders, LA, Sclafani, R A, Raynolds, M V, Reyland, ME, Anderson, S M, Quissell, DO

“…Apoptosis is a highly organized cellular process that is critical for maintaining glandular homeostasis. We have used primary rat salivary acinar cells from…”
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