Search Results - "Lima, Svetlana F."
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Genetic manipulation of gut microbes enables single-gene interrogation in a complex microbiome
Published in Cell (03-02-2022)“…Hundreds of microbiota genes are associated with host biology/disease. Unraveling the causal contribution of a microbiota gene to host biology remains…”
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Transferable Immunoglobulin A–Coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2022)“…Fecal microbiota transplantation (FMT) is an emerging treatment modality for ulcerative colitis (UC). Several randomized controlled trials have shown efficacy…”
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Adherent-invasive E. coli metabolism of propanediol in Crohn’s disease regulates phagocytes to drive intestinal inflammation
Published in Cell host & microbe (14-04-2021)“…Adherent-invasive E. coli (AIEC) are enriched in the intestinal microbiota of patients with Crohn’s disease (CD) and promote intestinal inflammation. Yet, how…”
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Alterations to the Gut Microbiome Impair Bone Strength and Tissue Material Properties
Published in Journal of bone and mineral research (01-06-2017)“…ABSTRACT Alterations in the gut microbiome have been associated with changes in bone mass and microstructure, but the effects of the microbiome on bone…”
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Milk microbiome and bacterial load following dry cow therapy without antibiotics in dairy cows with healthy mammary gland
Published in Scientific reports (14-08-2017)“…Preventive infusion of antibiotics in the mammary gland of cows consumes 11 tons/year of medically relevant antimicrobials, yet, this practice might not be…”
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The association of hyperketonemia with fecal and rumen microbiota at time of diagnosis in a case-control cohort of early lactation cows
Published in BMC veterinary research (21-11-2022)“…Many dairy cows experience a state of energy deficit as they transition from late gestation to early lactation. The aims of this study were to 1) determine if…”
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Assessment of cow and farm level risk factors associated with Ureaplasma diversum in pasture-based dairy systems - A field study
Published in Anais da Academia Brasileira de Ciências (01-07-2017)“…Potential risk factors for Ureaplasma diversum in the vaginal mucus of 1,238 dairy cows were included in a multivariate logistic regression model, based on the…”
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Prepartum and postpartum rumen fluid microbiomes: characterization and correlation with production traits in dairy cows
Published in Applied and Environmental Microbiology (01-02-2015)“…Microbes present in the rumen of dairy cows are essential for degradation of cellulosic and nonstructural carbohydrates of plant origin. The prepartum and…”
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Longitudinal metagenomic profiling of bovine milk to assess the impact of intramammary treatment using a third-generation cephalosporin
Published in Scientific reports (22-11-2016)“…Antimicrobial usage in food animals has a direct impact on human health, and approximately 80% of the antibiotics prescribed in the dairy industry are used to…”
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The upper respiratory tract microbiome and its potential role in bovine respiratory disease and otitis media
Published in Scientific reports (01-07-2016)“…The upper respiratory tract (URT) hosts a complex microbial community of commensal microorganisms and potential pathogens. Analyzing the composition and nature…”
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The bovine colostrum microbiome and its association with clinical mastitis
Published in Journal of dairy science (01-04-2017)“…In an effort to characterize colostrum microbial diversity and its potential associations with early-lactation clinical mastitis, we used high-throughput…”
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Eating for Two: Diet and the Microbiome in Ulcerative Colitis
Published in Journal of Crohn's and colitis (14-03-2022)Get full text
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Deciphering upper respiratory tract microbiota complexity in healthy calves and calves that develop respiratory disease using shotgun metagenomics
Published in Journal of dairy science (01-02-2017)“…Bovine respiratory disease (BRD) is a multifactorial disorder responsible for severe economic losses in dairy and feedlot herds. Advances in next-generation…”
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Shift of uterine microbiota associated with antibiotic treatment and cure of metritis in dairy cows
Published in Veterinary microbiology (01-02-2018)“…•Both time and treatment play a role in shaping uterine microbiota.•Ceftiofur was least effective in controlling Bacteroidetes, notably…”
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Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis
Published in Cell reports (Cambridge) (15-11-2022)“…Endoplasmic reticulum (ER) stress is associated with Crohn’s disease (CD), but its impact on host-microbe interaction in disease pathogenesis is not well…”
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The gut microbiome regulates the clinical efficacy of sulfasalazine therapy for IBD-associated spondyloarthritis
Published in Cell reports. Medicine (19-03-2024)“…Sulfasalazine is a prodrug known to be effective for the treatment of inflammatory bowel disease (IBD)-associated peripheral spondyloarthritis (pSpA), but the…”
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Metabolic utilization of propanediol by adherent-invasive E. coli regulates intestinal tissue immunity
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Crohn’s Disease (CD) has been associated with alterations in the intestinal microbiota, but the microbial mechanisms that regulate host immunity are…”
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1130 – Transferable Iga-Reactive Microbiota Stratify Clinical Response to Fmt for Ulcerative Colitis
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2019)Get full text
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