Search Results - "Lima, Patricia A"
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Regulation of androgen receptor signaling by ubiquitination during folliculogenesis and its possible dysregulation in polycystic ovarian syndrome
Published in Scientific reports (31-08-2017)“…Although chronic hyperandrogenism suppresses antral follicular development, a phenomenon often observed in polycystic ovarian syndrome (PCOS), whether and how…”
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Lack of Annexin A1 Exacerbates Inflammatory Response in Acute Endometritis Model
Published in Inflammation (01-06-2024)“…Annexin A1 (AnxA1) is a glucocorticoid-inducible protein and an important endogenous modulator of inflammation. However, its effect in the endometrial…”
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Neuropeptide Y regulates proliferation and apoptosis in granulosa cells in a follicular stage-dependent manner
Published in Journal of ovarian research (08-01-2020)“…The complex regulatory mechanism involved in ovarian follicular development is not completely understood. Neuronal neuropeptide Y (NPY) is involved in the…”
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Heterogeneity in composition of mouse uterine natural killer cell granules
Published in Journal of leukocyte biology (01-07-2012)“…Pregnancy‐associated mouse uNK cells constitutively secrete Vegfa from vesicles, and have the capability for induced secretion of Gzma from secretory, and…”
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The elusive MAESTRO gene: Its human reproductive tissue-specific expression pattern
Published in PloS one (13-04-2017)“…The encoded transcript of the Maestro-Male-specific Transcription in the developing Reproductive Organs (MRO) gene exhibits sexual dimorphic expression during…”
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Circulating progenitor and angiogenic cell frequencies are abnormally static over pregnancy in women with preconception diabetes: A pilot study
Published in PloS one (09-03-2017)“…Type 1 and 2 diabetes decrease the frequencies and functional capacities of circulating angiogenic cells (CAC). Diabetes also elevates gestational…”
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Polycystic ovary syndrome: possible involvement of androgen-induced, chemerin-mediated ovarian recruitment of monocytes/macrophages
Published in Biology of reproduction (01-10-2018)“…Polycystic ovary syndrome (PCOS) is a continuum of endocrine and reproductive disorders characterized by hyperandrogenism, antral follicle growth arrest, and…”
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Homing receptor expression is deviated on CD56+ blood lymphocytes during pregnancy in Type 1 diabetic women
Published in PloS one (20-03-2015)“…Type 1 Diabetes Mellitus (T1DM) is characterized by an augmented pro-inflammatory immune state. This contributes to the increased risk for gestational…”
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Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury
Published in The FASEB journal (01-01-2020)“…Mitochondrial fission is important in physiological processes, including coordination of mitochondrial and nuclear division during mitosis, and pathologic…”
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Ly49 receptors activate angiogenic mouse DBA+ uterine natural killer cells
Published in Cellular & molecular immunology (01-09-2014)“…In humans, specific patterns of killer immunoglobulin-like receptors (KIRs) expressed by uterine natural killer (uNK) cells are linked through HLA-C with…”
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PINK1‐induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension
Published in The FASEB journal (01-08-2021)“…Impaired mitochondrial fusion, due in part to decreased mitofusin 2 (Mfn2) expression, contributes to unrestricted cell proliferation and apoptosis‐resistance…”
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Mitochondria in human neutrophils mediate killing of Staphylococcus aureus
Published in Redox biology (01-02-2022)“…Neutrophils play a role in innate immunity and are critical for clearance of Staphylococcus aureus. Current understanding of neutrophil bactericidal effects is…”
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Recombinant human OVGP1 increases intracellular calcium and further potentiates the effects of progesterone on human sperm
Published in Journal of assisted reproduction and genetics (01-10-2022)“…Purpose To investigate the effects of recombinant human oviduct–specific glycoprotein (rHuOVGP1) alone and in combination with progesterone (P4) on…”
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DBA-Lectin Reactivity Defines Mouse Uterine Natural Killer Cell Subsets with Biased Gene Expression
Published in Biology of reproduction (01-10-2012)“…Endometrial decidualization, a process essential for blastocyst implantation in species with hemochorial placentation, is accompanied by an enormous but…”
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Leukocyte driven-decidual angiogenesis in early pregnancy
Published in Cellular & molecular immunology (01-11-2014)“…Successful pregnancy and long-term, post-natal maternal and offspring cardiac, vascular and metabolic health require key maternal cardiovascular adaptations…”
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Cytotoxicity and Regenerative Proliferation as the Mode of Action for Diuron-Induced Urothelial Carcinogenesis in the Rat
Published in Toxicological sciences (01-01-2010)“…Diuron, a substituted urea herbicide, is carcinogenic to the urinary bladder of rats at high dietary levels. Its proposed carcinogenic mode of action (MOA)…”
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Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site IQ Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus
Published in Journal of the American Heart Association (04-07-2023)“…Background As partial pressure of oxygen (pO2) rises with the first breath, the ductus arteriosus (DA) constricts, diverting blood flow to the pulmonary…”
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Ly49 receptors: innate and adaptive immune paradigms
Published in Frontiers in immunology (02-04-2014)“…The Ly49 receptors are type II C-type lectin-like membrane glycoproteins encoded by a family of highly polymorphic and polygenic genes within the mouse natural…”
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Surface-enhanced Raman scattering for the detection of polycystic ovary syndrome
Published in Biomedical optics express (01-02-2018)“…Polycystic ovary syndrome (PCOS) is a multi-factorial heterogeneous syndrome that affects many women of reproductive age. This work demonstrates how the…”
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Gestational Modification of Murine Spiral Arteries Does Not Reduce Their Drug-Induced Vasoconstrictive Responses In Vivo
Published in Biology of reproduction (01-12-2013)“…Dynamic control of maternal blood flow to the placenta is critical for healthy pregnancy. In many tissues, microvasculature arteries control the flow. The…”
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