Search Results - "Lima, Maurício T."

Analysis of the Genomic Features and Evolutionary History of Pithovirus-Like Isolates Reveals Two Major Divergent Groups of Viruses by Queiroz, Victória F, Carvalho, João Victor R P, de Souza, Fernanda G, Lima, Maurício T, Santos, Juliane D, Rocha, Kamila L S, de Oliveira, Danilo B, Araújo, Jr, João Pessoa, Ullmann, Leila Sabrina, Rodrigues, Rodrigo A L, Abrahão, Jônatas S

“…New representatives of the phylum have been rapidly described in the last decade. Despite this, not all viruses of this phylum are allocated to recognized…”
Get full text

Heterotropic Modulation of Amylin Fibrillation by Small Molecules: Implications for Formulative Designs by Sinézia, Celimar, Lima, Luís Maurício T. R.

“…Control of amylin agglomeration is of interest for both the study of pathophysiology and the design of amylin-based pharmaceutical products. Here we report the…”
Get full text

Biologically produced silver chloride nanoparticles from B. megaterium modulate interleukin secretion by human adipose stem cell spheroids by Charelli, Letícia E., Müller, Nathalia, Silva, Karina R., Lima, Luís Maurício T. R., Sant’Anna, Celso, Baptista, Leandra S.

“…Stem cell tissue constructs are likely to come into contact with silver-based nanoparticles—such as silver chloride nanoparticles (AgCl–NPs)—used as…”
Get full text

The toxic nature of murine amylin and the immune responsivity of pancreatic islet to conformational antibody in mice by Erthal, Luiza C. S., Jotha-Mattos, Luana, Lara, Flávio Alves, dos Reis, Sabrina Alves, de Oliveira Pascarelli, Bernardo Miguel, Costa, Cinthia Melo, Souza, Kleber L. A., Lima, Luís Maurício T. R.

“…The human amylin is a pancreatic peptide hormone found in hyperhormonemic state along with insulin in subclinical diabetes. Amylin has been associated with the…”
Get full text

Microbiota is an essential element for mice to initiate a protective immunity against Vaccinia virus by Lima, Maurício T., Andrade, Ana C. S. P., Oliveira, Graziele P., Calixto, Rafael S., Oliveira, Danilo B., Souza, Éricka L. S., Trindade, Giliane S., Nicoli, Jacques R., Kroon, Erna G., Martins, Flaviano S., Abrahão, Jônatas S.

“…The gastrointestinal tract of vertebrates harbors one of the most complex ecosystems known in microbial ecology and this indigenous microbiota almost always…”
Get full text

Safety and protective effectiveness of two strains of Lactobacillus with probiotic features in an experimental model of salmonellosis by Steinberg, Raphael S, Silva, Lilian C S, Souza, Tássia C, Lima, Maurício T, de Oliveira, Nayara L G, Vieira, Leda Q, Arantes, Rosa M E, Miyoshi, Anderson, Nicoli, Jacques R, Neumann, Elisabeth, Nunes, Alvaro C

“…Two strains of Lactobacillus, previously isolated from bovine faeces and tested in vitro for properties desired in probiotics, were evaluated for their in vivo…”
Get full text

Nutrient‐sensing amyloid metastasis by Lima, Luís Maurício T. R., Sisnande, Tháyna

“…Amyloids are organized suprastructural polypeptide arrangements. The prevalence of amyloid‐related processes of pathophysiological relevance has been linked to…”
Get full text

Sustained release and pharmacologic evaluation of human glucagon-like peptide-1 and liraglutide from polymeric microparticles by Icart, Luis Peña, Souza, Fernando Gomes de, Lima, Luís Maurício T. R.

“…The GLP1-receptor agonists exert regulatory key roles in diabetes, obesity and related complications. Here we aimed to develop polymeric microparticles loaded…”
Get full text

Polymeric microparticle systems for modified release of glucagon-like-peptide-1 receptor agonists by Icart, Luis Peña, Souza, Fernando Gomes, Lima, Luís Maurício T. R.

“…Type 2 diabetes is a fast-growing worldwide epidemic. Despite the multiple therapies available to treat type 2 diabetes, the disease is not correctly managed…”
Get full text

Recognition by the Thyroid Hormone Receptor of Canonical DNA Response Elements by Figueira, Ana Carolina Migliorini, Lima, Luís Maurício T. R, Lima, Leonardo H. F, Ranzani, Americo T, dos Santos Mule, Guilherme, Polikarpov, Igor

“…To shed more light on the molecular requirements for recognition of thyroid response elements (TREs) by thyroid receptors (TRs), we compared the specific…”
Get full text

Oral delivery of the amylin receptor agonist pramlintide by Sinézia, Celimar, Sisnande, Tháyna, Icart, Luis Peña, Lima, Luís Maurício T. R.

“…Amylin receptor agonism safely benefit diabetic patients, reducing the insulin requirements and glycemic excursions. Pramlintide is the triple proline human…”
Get full text

Monitoring asparaginase activity by Lima, Luís Maurício T R, Araujo, Talita S, Almeida, Fábio C L, Almeida, Marcius S

Get full text

Physico-chemical stability of co-formulation of PEGylated human amylin with insulin by Sinésia, Celimar, do Nascimento, Caio Victor M. F., Lacativa, Paulo G. S., Lima, Luís Maurício T. R.

“…Since the discovery of amylin no combined formulation with insulin has been made available. Amylin or its triple proline analog pramlintide are not compatible…”
Get full text

Genomic Surveillance of Monkeypox Virus, Minas Gerais, Brazil, 2022 by Guimarães, Natália R, Tomé, Luiz Marcelo R, Lamounier, Ludmila O, Silva, Marcos Vinícius F, Lima, Maurício T, da Costa, Alana Vitor B, Luiz, Kelly Cristina M, de Jesus, Ronaldo, Trindade, Giliane de S, Oliveira, Danilo B, da Fonseca, Flávio G, Fernandes, Ana Paula S M, de Oliveira, Jaqueline S, Moura, Josiane B P, Kroon, Erna G, Giovanetti, Marta, Fonseca, Vagner, Alcantara, Luiz, Adelino, Talita Emile R, de Melo Iani, Felipe C

“…Phylogenetic analysis of 34 monkeypox virus genome sequences isolated from patients in Minas Gerais, Brazil, revealed initial importation events in early June…”
Get full text

Unambiguous characterization of PEGylation site on human amylin by two‐dimensional nuclear magnetic resonance spectroscopy by Lima, Luís Maurício T. R., Araújo, Talita Stelling, Almeida, Marcius da Silva

“…Amylin is a 37‐residue peptide hormone, which is co‐secreted with insulin and prevents postprandial spikes in blood glycemia by slowing gastric emptying and…”
Get full text

Allosteric function and dysfunction of the prion protein by Linden, Rafael, Cordeiro, Yraima, Lima, Luis Mauricio T. R.

“…Transmissible spongiform encephalopathies (TSEs) are neurodegenerative diseases associated with progressive oligo- and multimerization of the prion protein…”
Get full text

Monoconjugation of Human Amylin with Methylpolyethyleneglycol by Sisnande, Tháyna, Guerreiro, Luiz Henrique, Braga, Raquel R, Jotha-Mattos, Luana, Erthal, Luiza C S, Tinoco, Priscilla, Ferreira, Bruno M, Lima, Luís Maurício T R

“…Amylin is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. The therapeutic restoration of…”
Get full text

Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins by Silva, Jerson L, Vieira, Tuane C. R. G, Gomes, Mariana P. B, Bom, Ana Paula Ano, Lima, Luis Mauricio T. R, Freitas, Monica S, Ishimaru, Daniella, Cordeiro, Yraima, Foguel, Debora

“…Protein misfolding has been implicated in a large number of diseases termed protein- folding disorders (PFDs), which include Alzheimer’s disease, Parkinson’s…”
Get full text

Preparation and Characterization of PEGylated Amylin by Guerreiro, Luiz Henrique, Guterres, Mariana F. A. N., Melo-Ferreira, Bruno, Erthal, Luiza C. S., da Silva Rosa, Marcela, Lourenço, Daniela, Tinoco, Priscilla, Lima, Luís Maurício T. R.

“…Amylin is a pancreatic hormone that plays important roles in overall metabolism and in glucose homeostasis. The therapeutic restoration of postprandial and…”
Get full text

Structural Insights into the Interaction between Prion Protein and Nucleic Acid by Lima, Luis Maurício T. R, Cordeiro, Yraima, Tinoco, Luzineide W, Marques, Adriana F, Oliveira, Cristiano L. P, Sampath, Srisailam, Kodali, Ravindra, Choi, Gildon, Foguel, Débora, Torriani, Iris, Caughey, Byron, Silva, Jerson L

“…The infectious agent of transmissible spongiform encephalopathies (TSE) is believed to comprise, at least in part, the prion protein (PrP). Other molecules can…”
Get full text