Search Results - "Lima, Marcelo Andrade de"
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Analysis of Heparin Samples by Attenuated Total Reflectance Fourier-Transform Infrared Spectroscopy in the Solid State
Published in ACS central science (22-03-2023)“…Heparin is a polydisperse, heterogeneous polysaccharide of the glycosaminoglycan (GAG) class that has found widespread clinical use as a potent anticoagulant…”
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Neuroprogenitor Cells From Patients With TBCK Encephalopathy Suggest Deregulation of Early Secretory Vesicle Transport
Published in Frontiers in cellular neuroscience (13-01-2022)“…Biallelic pathogenic variants in TBCK cause encephaloneuropathy, infantile hypotonia with psychomotor retardation, and characteristic facies 3 (IHPRF3). The…”
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The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models
Published in Frontiers in pharmacology (06-08-2021)“…The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has caused a significant number of fatalities and worldwide disruption. To identify…”
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Nebulized enriched heparin to treat no critical patients with Sars-Cov-2: Triple-blind clinical trial
Published in Medicine (Baltimore) (23-12-2021)“…Coronavirus disease 2019 (COVID-19) is a viral respiratory disease that spreads rapidly, reaching pandemic status, causing the collapse of numerous health…”
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Cathepsin B-associated Activation of Amyloidogenic Pathway in Murine Mucopolysaccharidosis Type I Brain Cortex
Published in International journal of molecular sciences (20-02-2020)“…Mucopolysaccharidosis type I (MPS I) is caused by genetic deficiency of α-l-iduronidase and impairment of lysosomal catabolism of heparan sulfate and dermatan…”
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Safety assessment of medicines available in the ‘Brazilian list of essential medicines’ in the older persons according to the Beers Criteria
Published in Geriatrics, Gerontology and Aging (Online) (01-06-2023)“…Objective: To describe the safety of medicines available in the “Brazilian List of Essential Medicines” (RENAME/2022) for the main comorbidities that affect…”
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Quinolone resistance and ornithine decarboxylation activity in lactose-negative Escherichia coli
Published in Brazilian journal of microbiology (01-07-2015)“…Quinolones and fluoroquinolones are widely used to treat uropathogenic Escherichia coli infections. Bacterial resistance to these antimicrobials primarily…”
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Impaired thermoregulation in spontaneously hypertensive rats during physical exercise is related to reduced hypothalamic neuronal activation
Published in Pflügers Archiv (01-12-2020)“…This study aimed to evaluate the physical exercise-induced neuronal activation in brain nuclei controlling thermoregulatory responses in hypertensive and…”
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Highly Sensitive Poly-N-isopropylacrylamide Microgel-based Electrochemical Biosensor for the Detection of SARS-COV-2 Spike Protein
Published in Biomedical and environmental sciences (01-03-2023)“…Late 2019 witnessed the outbreak and widespread transmission of coronavirus disease 2019 (COVID-19), a new, highly contagious disease caused by novel severe…”
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New anti-angiogenic compound based on chemically modified heparin
Published in Graefe's archive for clinical and experimental ophthalmology (01-12-2022)“…Purpose The purpose of this study was to measure the anti-angiogenic effect of N-desulfated Re–N-acetylated, a chemically modified heparin (mHep). Methods In…”
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Obesity, Inflammation, and Exercise Training: Relative Contribution of iNOS and eNOS in the Modulation of Vascular Function in the Mouse Aorta
Published in Frontiers in physiology (07-09-2016)“…The understanding of obsesity-related vascular dysfunction remains controversial mainly because of the diseases associated with vascular injury. Exercise…”
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Lepstospira interrogans shotgun phage display identified LigB as a heparin-binding protein
Published in Biochemical and biophysical research communications (02-11-2012)“…► LigB protein that was selected by screening a shotgun phage display library HSPG. ► F11 binds heparin. ► rLB-Ct binds to heparin and binds to fibroblasts,…”
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Nitric Oxide Participation in Thermoregulatory Adjustments During Physical Exercise in Spontaneously Hypertensive Rats
Published in The FASEB journal (01-04-2017)“…Abstract only This study aimed to investigate the nitric oxide participation in thermoregulatory adjustments during physical exercise in spontaneously…”
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Central NO‐signaling is important to PVN activation, improving heat dissipation and exercise performance
Published in The FASEB journal (01-04-2012)“…Abstract only To investigate whether central NO‐signaling is involved in activation of PVN induced by treadmill running, L‐NAME (n=9) or SALINE (n=9) were…”
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Effects of physical training on neuronal hypothalamic activation induced by exercise
Published in The FASEB journal (01-04-2012)“…Abstract only We assessed whether the effects of physical training on heat balance are followed by hypothalamic activation induced by exercise. After physical…”
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Leptospira interrogans shotgun phage display identified LigB as a heparin-binding protein
Published in Biochemical and biophysical research communications (02-11-2012)“…LigB is an adhesin from pathogenic Leptospira that is able to bind to extracellular matrix and is considered a virulence factor. A shotgun phage display…”
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