Search Results - "Lima, Mércia P."
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Characterization of the renal renin-angiotensin system in transgenic mice that express rat tonin
Published in Journal of the renin-angiotensin-aldosterone system (01-12-2015)“…Introduction: Tonin is an enzyme that is able to generate angiotensin II (Ang II) from angiotensin I (Ang I) or directly from angiotensinogen. Our goal was to…”
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2
Increased blood pressure and water intake in transgenic mice expressing rat tonin in the brain
Published in Biological chemistry (01-04-2010)“…Tonin is a serine proteinase of the kallikrein family that can produce angiotensin II directly from angiotensinogen. To clarify the importance of this enzyme…”
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3
Peripheral glucose metabolism is altered by epileptic seizures
Published in Metabolic brain disease (01-03-2008)“…The aim of the present study was to investigate the status of jejunal absorption and peripheral metabolism of glucose in Wistar Audiogenic Rats (WAR), a…”
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4
Increased activity of the renin–angiotensin and sympathetic nervous systems is required for regulation of the blood pressure in rats fed a low‐protein diet
Published in Experimental physiology (01-01-2013)“…New Findings • What is the central question of this study? Is the increase in blood pressure observed in rats fed a low protein diet due to overactivation of…”
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5
Tonin expression in the rat brain and tonin-mediated central production of angiotensin II
Published in Physiology & behavior (01-06-2002)“…Tonins are serine proteinases mainly found in the rat submandibular gland, which are capable of generating the pressor octapeptide angiotensin II (Ang II) not…”
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6
Cardiovascular and eletrocardiographic parameters after tonin administration in Wistar rats
Published in Regulatory peptides (10-02-2013)“…In order to understand the mechanisms of interaction between tonin–angiotensin and renin–angiotensin systems (RAS) we evaluated, “in vivo” and “in vitro”, in…”
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Cardiovascular and electrocardiographic parameters after tonin administration in Wistar rats
Published in Regulatory peptides (10-02-2013)“…In order to understand the mechanisms of interaction between tonin-angiotensin and renin-angiotensin systems (RAS) we evaluated, "in vivo" and "in vitro", in…”
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8
Antiserum for insulin radioimmunoassay generated by an insulin derivative devoid of hypoglycemic activity
Published in Journal of immunoassay (Monticello, N.Y.) (01-03-1993)“…A tetraiodinated derivative of bovine insulin, prepared at pH 1 with stable iodine, was unable to cause signs of hypoglycemia in doses up to 2.4 micrograms/g…”
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