Search Results - "Lima, Dênis P DE"
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Catalyst- and metal-free C(sp2)–H bond selenylation of (N-hetero)-arenes using diselenides and trichloroisocyanuric acid at room temperature
Published in Scientific reports (31-08-2023)“…In this paper, we report an eco-friendly approach for the C( sp 2 )–H bond selenylation of imidazopyridines and other N -heteroarenes as well as simple arenes…”
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2
Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity
Published in Bioorganic & medicinal chemistry letters (15-08-2013)“…We have devised a procedure for the synthesis of analogs of combretastatin A-4 (CA-4) containing sulfur and selenium atoms as spacer groups between the…”
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3
A potent larvicidal agent against Aedes aegypti mosquito from cardanol
Published in Anais da Academia Brasileira de Ciências (01-05-2017)“…Cardanol is a constituent of Cashew Nut Shell Liquid that presents larvicidal activity against Aedes aegypti. The isolation of cardanol is somewhat…”
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4
Design, synthesis and identification of novel molecular hybrids based on naphthoquinone aromatic hydrazides as potential trypanocide and leishmanicidal agents
Published in Anais da Academia Brasileira de Ciências (01-01-2024)“…In pursuit of potential agents to treat Chagas disease and leishmaniasis, we report the design, synthesis, and identification novel naphthoquinone…”
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5
Synthesis method for thiosulfonate and report of its insecticidal activity in Anagasta kuehniella (Lepidoptera: Pyralidae)
Published in International journal of molecular sciences (19-11-2012)“…Insect pests have caused economic losses valued at billions of dollars in agricultural production. Anagasta kuehniella (Zeller), the Mediterranean flour moth,…”
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6
SYNTHESIS AND EVALUATION OF OCTOCRYLENE-INSPIRED COMPOUNDS FOR UV-FILTER ACTIVITY
Published in Química Nova (01-01-2014)“…Octocrylene (2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate) is present in several sunscreens and is known to work synergistically with UV filters. We prepared…”
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7
SYNTHESIS AND BIOLOGICAL ACTIVITY OF SULFUR COMPOUNDS SHOWING STRUCTURAL ANALOGY WITH COMBRETASTATIN A-4
Published in Química nova (01-01-2013)“…We extended our previous exploration of sulfur bridges as bioisosteric replacements for atoms forming the bridge between the aromatic rings of combretastatin…”
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Straightforward synthesis of cytosporone analogs AMS35AA and AMS35BB
Published in Anais da Academia Brasileira de Ciências (01-01-2021)“…Abstract Cytosporones, a class of octaketide resorcinolic lipids, have drawn the attention of researchers for exhibiting a number of notable biological…”
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9
Design, synthesis and fluorescence analysis of potential fluorescent markers based on cardanol and glycerol
Published in Dyes and pigments (01-06-2017)“…We report the synthesis and fluorescent properties of 1,4-disubstituted-1,2,3-triazoles (1a-c) based on pollutant wastes and by-products from the cashew and…”
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10
Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol‑Based β-Amino Alcohol Derivatives
Published in Journal of the Brazilian Chemical Society (01-03-2018)“…The synthesis of novel amino alcohol derivatives based on cardanol and glycerol were achieved in good yields and characterized by 1H and 13C NMR (nuclear…”
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11
Chemotherapeutic Mechanism of Action of the Synthetic Resorcinolic Methyl 3,5-dimethoxy-2-octanoylbenzoate
Published in Chemical research in toxicology (19-02-2024)“…Resorcinolic lipids are described as potential examples of selective chemotherapeutic adjuvants that can enhance the effects of cyclophosphamide (CYC) while…”
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12
Cu(I)-phosphine complex: An efficient catalyst for synthesis of 3-indole derivatives through one-pot MCR under mild conditions
Published in Synthetic communications (02-01-2018)“…An efficient copper (I) halotriphenylphosphine catalyzed one-pot multicomponent reaction (MCR) of 3-substituted indole derivatives has been developed using a…”
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13
Bioprospecting insecticidal compounds from plants native to Mato Grosso do Sul, Brazil
Published in Acta botânica brasilica (01-12-2008)“…This paper reports on an evaluation of the insecticidal activity of extracts prepared from leaves of Tapirira guianensis Aubl. (Anacardiaceae), Attalea…”
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14
Investigation of the Potential Targets behind the Promising and Highly Selective Antileishmanial Action of Synthetic Flavonoid Derivatives
Published in ACS infectious diseases (13-10-2023)“…Leishmaniases are among the neglected tropical diseases that still cause devastating health, social, and economic consequences to more than 350 million people…”
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15
In vitro cytotoxic activity of Brazilian Middle West plant extracts
Published in Revista brasileira de farmacognosia (01-06-2011)“…Cytotoxic activity of eight plant extracts, native from the Mid-West of Brazil comprising Cerrado, Pantanal and semideciduous forest, was evaluated for…”
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Synthesis and Antioxidant and Antimicrobial Properties of β-Hydroxy Sulfides, Sulfoxides, and Sulfones Derived from Cardanol and Glycerol Derivatives
Published in Journal of the Brazilian Chemical Society (2020)“…Natural and synthetic sulfur-bearing organic compounds have many applications in medicinal chemistry. This article reports the preparation of amphiphilic…”
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17
Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2 + 2 + 2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi
Published in Bioorganic & medicinal chemistry (01-08-2020)“…This article provides a comprehensive outline of reactions involving over 120 compounds aimed at the discovery of new quinone-based frameworks with activity…”
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18
1H and 13C NMR spectral data of bioactive cage-like polycyclic compounds
Published in Magnetic resonance in chemistry (01-05-2010)“…Bioactive cage‐like polycyclic compounds have attracted the attention of several research groups because of their unique appearance and their biological…”
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l-Hypaphorine and d-hypaphorine: Specific antiacetylcholinesterase activity in rat brain tissue
Published in Bioorganic & medicinal chemistry letters (01-09-2021)“…[Display omitted] Acetylcholinesterase (AChEis) inhibitors are used to treat neurodegenerative diseases like Alzheimer’s disease (AD). l-Hypaphorine (l-HYP) is…”
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Assessment of genotoxic effects of (4-methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone in human lymphocytes
Published in Toxicology in vitro (01-12-2011)“…► In this study we evaluated the genotoxic potential of a phenstatin compound, a tubulin inhibitor. ► The compound was able to produces DNA-damage and…”
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