Search Results - "Lim, Stephanie H."

Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis by Ho, Vincent, Chung, Liping, Singh, Amandeep, Lea, Vivienne, Abubakar, Askar, Lim, Stephanie H, Ng, Weng, Lee, Mark, de Souza, Paul, Shin, Joo-Shik, Lee, Cheok Soon

“…The MRE11/RAD50/NBS1 (MRN) complex plays an essential role in detecting and repairing double-stranded breaks, and thus the potential roles of MRE11, RAD50 and…”
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Patients' perception of the benefits of palliative systemic therapy for advanced cancer by Subramaniam, Shalini, Adams, Diana H, Tognela, Annette, Roncolato, Felicia, Yip, Po Y, Lim, Stephanie H-S, Roohullah, Aflah, Stockler, Martin R, Kiely, Belinda

“…Patients with advanced cancer who misunderstand their prognosis and chance of cure tend to overestimate the likely benefits of palliative systemic therapy. To…”
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The potential value of immunotherapy in colorectal cancers: review of the evidence for programmed death-1 (PD-1) inhibitor therapy by Toh, James W.T, de Souza, Paul, Lim, Stephanie H, Singh, Puneet, Chua, Wei, Ng, Weng, Spring, Kevin J

“…Abstract Background Colorectal cancers have been identified as potential targets for immunotherapy with programmed cell death-1 (PD-1) inhibitors. Method…”
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Aberrant Expression of RAD52, Its Prognostic Impact in Rectal Cancer and Association with Poor Survival of Patients by Ho, Vincent, Chung, Liping, Singh, Amandeep, Lea, Vivienne, Abubakar, Askar, Lim, Stephanie H, Chua, Wei, Ng, Weng, Lee, Mark, Roberts, Tara L, de Souza, Paul, Lee, Cheok Soon

“…The DNA damage response enables cells to survive and maintain genome integrity. RAD52 is a DNA-binding protein involved in the homologous recombination in DNA…”
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MRE11 and ATM Expression Levels Predict Rectal Cancer Survival and Their Association with Radiotherapy Response by Ho, Vincent, Chung, Liping, Revoltar, Maxine, Lim, Stephanie H, Tut, Thein-Ga, Abubakar, Askar, Henderson, Chris J, Chua, Wei, Ng, Weng, Lee, Mark, De Souza, Paul, Morgan, Matthew, Lee, C Soon, Shin, Joo-Shik

“…Aberrant expression of DNA repair proteins is associated with poor survival in cancer patients. We investigated the combined expression of MRE11 and ATM as a…”
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New frontiers in circulating tumor cell analysis: A reference guide for biomolecular profiling toward translational clinical use by Becker, Therese M., Caixeiro, Nicole J., Lim, Stephanie H., Tognela, Annette, Kienzle, Norbert, Scott, Kieran F., Spring, Kevin J., Souza, Paul

“…Circulating tumor cells (CTCs) are now routinely isolated from blood, and measurement of CTC concentrations appears to correlate well with survival in patients…”
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Prognostic Impact of TP53 Mutations and Tumor Mutational Load in Colorectal Cancer by Ho, Vincent, Chung, Liping, Lim, Stephanie H., Ma, Yafeng, Wang, Bin, Lea, Vivienne, Abubakar, Askar, Ng, Weng, Lee, Mark, Roberts, Tara L., Chua, Wei, Lee, C. Soon

“…The DNA damage response (DDR) is critical for maintaining genome stability, and abnormal DDR—resulting from mutations in DNA damage-sensing and repair…”
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Association Between Microsatellite Instability Status and Peri-Operative Release of Circulating Tumour Cells in Colorectal Cancer by Toh, James W T, Lim, Stephanie H, MacKenzie, Scott, de Souza, Paul, Bokey, Les, Chapuis, Pierre, Spring, Kevin J

“…Microsatellite instability (MSI) in colorectal cancer (CRC) is a marker of immunogenicity and is associated with an increased abundance of tumour infiltrating…”
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Prognostic Significance of MRE11 Overexpression in Colorectal Cancer Patients by Ho, Vincent, Chung, Liping, Wilkinson, Kate, Lea, Vivienne, Lim, Stephanie H, Abubakar, Askar, Ng, Weng, Lee, Mark, Roberts, Tara L, Chua, Wei, Lee, Cheok Soon

“…Meiotic recombination 11 (MRE11) plays a critical role in the DNA damage response and maintenance of genome stability and is associated with the prognosis for…”
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Effect of neoadjuvant chemoradiation on tumor-infiltrating/associated lymphocytes in locally advanced rectal cancers by Lim, Stephanie H, Chua, Wei, Cheng, Christina, Descallar, Joseph, Ng, Weng, Solomon, Michael, Bokey, Les, Wong, Karen, Lee, Mark T, de Souza, Paul, Shin, Joo-Shik, Lee, Cheok Soon

“…Lymphocytes and natural killer cells (NK) appear to be important in colorectal cancer. Their role in chemoradiotherapy for rectal cancers is unclear. We…”
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Microsatellite Instability Testing and Prognostic Implications in Colorectal Cancer by Ho, Vincent, Chung, Liping, Wilkinson, Kate, Ma, Yafeng, Rutland, Tristan, Lea, Vivienne, Lim, Stephanie H, Abubakar, Askar, Ng, Weng, Lee, Mark, Roberts, Tara L, Becker, Therese M, Mackenzie, Scott, Chua, Wei, Lee, Cheok Soon

“…Given the crucial predictive implications of microsatellite instability (MSI) in colorectal cancer (CRC), MSI screening is commonly performed in those with and…”
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Predictive and prognostic value of circulating tumor cell detection in lung cancer: A clinician's perspective by Tognela, Annette, Spring, Kevin J, Becker, Therese, Caixeiro, Nicole J, Bray, Victoria J, Yip, Po Yee, Chua, Wei, Lim, Stephanie H, de Souza, Paul

“…Abstract There is increasing evidence for the use of circulating tumor cells (CTCs) as a “liquid biopsy” for early detection of lung cancer recurrence,…”
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Treatment and Outcomes of Oligometastatic Colorectal Cancer Limited to Lymph Node Metastases by Mathai, Vinod Kalapurackal, Aung, Soe Yu, Wong, Vanessa, Dunn, Catherine, Shapiro, Jeremy, Jalali, Azim, Wong, Rachel, Lee, Margaret, Tie, Jeanne, Ananda, Sumitra, Kosmider, Suzanne, Lim, Stephanie H, Caird, Susan, Burge, Matthew, Dean, Andrew, Gibbs, Peter, Nott, Louise

“…The optimal management of isolated distant lymph node metastases (IDLNM) from a colorectal primary, is not clearly established. We aimed to analyze the…”
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Circulating Tumour Cell Associated MicroRNA Profiles Change during Chemoradiation and Are Predictive of Response in Locally Advanced Rectal Cancer by Lim, Stephanie H, Chua, Wei, Ng, Weng, Ip, Emilia, Marques, Tania M, Tran, Nham T, Gama-Carvalho, Margarida, Asghari, Ray, Henderson, Christopher, Ma, Yafeng, de Souza, Paul, Spring, Kevin J

“…Locally advanced rectal cancer (LARC) has traditionally been treated with trimodality therapy consisting of neoadjuvant radiation +/− chemotherapy, surgery,…”
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Early Postoperative Low Expression of RAD50 in Rectal Cancer Patients Associates with Disease-Free Survival by Ho, Vincent, Chung, Liping, Singh, Amandeep, Lea, Vivienne, Revoltar, Maxine, Lim, Stephanie H, Tut, Thein-Ga, Ng, Weng, Lee, Mark, de Souza, Paul, Shin, Joo-Shik, Soon Lee, Cheok

“…Molecular biomarkers have the potential to predict response to the treatment of rectal cancer. In this study, we aimed to evaluate the prognostic and…”
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Outcomes of Ethnic Minority Groups with Node-Positive, Non-Metastatic Breast Cancer in Two Tertiary Referral Canters in Sydney, Australia by Lim, Stephanie H, Delaney, Geoff P, Descallar, Joseph, Sayaloune, Phan, Papadatos, George, de Souza, Paul

“…Purpose: There is a lack of information in ethnic minority groups with regard to presentation and treatment of early node-positive breast cancer. We carried…”
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Outcomes of ethnic minority groups with node-positive, non-metastatic breast cancer in two tertiary referral centers in Sydney, Australia by Lim, Stephanie H, Delaney, Geoff P, Descallar, Joseph, Sayaloune, Phan, Papadatos, George, de Souza, Paul

“…There is a lack of information in ethnic minority groups with regard to presentation and treatment of early node-positive breast cancer. We carried out a…”
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Abstract 1942: Change in serum microRNA expression during neoadjuvant chemoradiation for rectal cancer by Lim, Stephanie H., De Souza, Paul, Chua, Wei, Ng, Weng, Harris, Benjamin, Cowley, Mark J., Spring, Kevin

“…Abstract Introduction MicroRNAs (miRNA) expression may change with treatment and influence responses in locally advanced rectal cancer (LARC) making them…”
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