Search Results - "Lim, Seok Jong"

Essential role of interferon regulatory factor 4 (IRF4) in immune cell development by Nam, Sorim, Lim, Jong-Seok

“…The family of interferon regulatory factors, which includes nine mammalian members (IRF1–IRF9), acts as transcription factors for interferons and thus exerts…”
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Emerging roles of MITF as a crucial regulator of immunity by Lee, Aram, Lim, Jihyun, Lim, Jong-Seok

“…Microphthalmia-associated transcription factor (MITF), a basic helix-loop-helix leucine zipper transcription factor (bHLH-Zip), has been identified as a…”
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Arabidopsis thaliana homeobox 12 (ATHB12), a homeodomain‐leucine zipper protein, regulates leaf growth by promoting cell expansion and endoreduplication by Hur, Yoon‐Sun, Um, Ji‐Hyun, Kim, Sunghan, Kim, Kyunga, Park, Hee‐Jung, Lim, Jong‐Seok, Kim, Woo‐Young, Jun, Sang Eun, Yoon, Eun Kyung, Lim, Jun, Ohme‐Takagi, Masaru, Kim, Donggiun, Park, Jongbum, Kim, Gyung‐Tae, Cheon, Choong‐Ill

“…Arabidopsis thaliana homeobox 12 (ATHB12), a homeodomain‐leucine zipper class I (HD‐Zip I) gene, is highly expressed in leaves and stems, and induced by…”
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Kazinol U inhibits melanogenesis through the inhibition of tyrosinase‐related proteins via AMP kinase activation by Lim, Jihyun, Nam, Sorim, Jeong, Ji Hye, Kim, Min Jung, Yang, Young, Lee, Myeong‐Sok, Lee, Hee Gu, Ryu, Jae‐Ha, Lim, Jong‐Seok

“…Background and Purpose Kazinol U is a prenylated flavan isolated from an extract of Broussonetia kazinoki Sieb (Moraceae). Kazinol U has shown cytoprotective…”
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Interferon regulatory factor 4 (IRF4) controls myeloid‐derived suppressor cell (MDSC) differentiation and function by Nam, Sorim, Kang, Kyeongah, Cha, Jae Seon, Kim, Jung Woo, Lee, Hee Gu, Kim, Yonghwan, Yang, Young, Lee, Myeong‐Sok, Lim, Jong‐Seok

“…IRF4 reduction induced by tumor formation can increase the number of MDSCs, where an increase in IRF4 expression may infringe immune suppressive function…”
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N-myc downstream-regulated gene 2 (NDRG2) suppresses the epithelial–mesenchymal transition (EMT) in breast cancer cells via STAT3/Snail signaling by Kim, Myung-Jin, Lim, Jihyun, Yang, Young, Lee, Myeong-Sok, Lim, Jong-Seok

“…Highlights • NDRG2 overexpression inhibits Snail expression in breast cancer cells. • NDRG2 overexpression reduces activation of STAT3. • NDRG2 interrupts the…”
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Anticancer Effect of E26 Transformation-Specific Homologous Factor through the Induction of Senescence and the Inhibition of Epithelial–Mesenchymal Transition in Triple-Negative Breast Cancer Cells by Lim, Soyoung, Lim, Jihyun, Lee, Aram, Kim, Keun-Il, Lim, Jong-Seok

“…The aim of the present study was to evaluate the effect of ETS homologous factor (EHF) in malignant breast cancer cells. The overexpression and knockdown of…”
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NDRG2 Expression in Breast Cancer Cells Downregulates PD-L1 Expression and Restores T Cell Proliferation in Tumor-Coculture by Lee, Aram, Lim, Soyoung, Oh, Juyeong, Lim, Jihyun, Yang, Young, Lee, Myeong-Sok, Lim, Jong-Seok

“…(1) Background: The aim of the present study was to evaluate the effect of NDRG2 expression in regulating PD-L1 or PD-L2 on malignant breast cancer cells. (2)…”
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Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages by Waqas, Syed F Hassnain, Hoang, Anh Cuong, Lin, Ya-Tin, Ampem, Grace, Azegrouz, Hind, Balogh, Lajos, Thuróczy, Julianna, Chen, Jin-Chung, Gerling, Ivan C, Nam, Sorim, Lim, Jong-Seok, Martinez-Ibañez, Juncal, Real, José T, Paschke, Stephan, Quillet, Raphaëlle, Ayachi, Safia, Simonin, Frédéric, Schneider, E Marion, Brinkman, Jacqueline A, Lamming, Dudley W, Seroogy, Christine M, Röszer, Tamás

“…The quantity and activation state of adipose tissue macrophages (ATMs) impact the development of obesity-induced metabolic diseases. Appetite-controlling…”
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Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism by Jeong, Ae Lee, Ka, Hye In, Han, Sora, Lee, Sunyi, Lee, Eun‐Woo, Soh, Su Jung, Joo, Hyun Jeong, Sumiyasuren, Buyanravjkh, Park, Ji Young, Lim, Jong‐Seok, Park, Jong Hoon, Lee, Myung Sok, Yang, Young

“…In most mammalian cells, the primary cilium is a microtubule‐enriched protrusion of the plasma membrane and acts as a key coordinator of signaling pathways…”
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Protein phosphatase 1B dephosphorylates Rho guanine nucleotide dissociation inhibitor 1 and suppresses cancer cell migration and invasion by Cho, Hee Jun, Kim, Jong-Tae, Lee, Seon-Jin, Hwang, Yo Sep, Park, Sang Yoon, Kim, Bo-Yeon, Yoo, Jiyun, Hong, Kwan Soo, Min, Jeong-Ki, Lee, Chul-Ho, Lim, Jong-Seok, Yoon, Suk Ran, Choi, Inpyo, Choe, Yong-Kyung, Lee, Hee Gu

“…Rho GTPases control a wide range of cellular processes, and their deregulation is associated with promotion of an aggressive and metastatic tumor phenotype in…”
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Adiponectin-Activated AMPK Stimulates Dephosphorylation of AKT through Protein Phosphatase 2A Activation by KIM, Kun-Yong, BAEK, Ahmi, HWANG, Ji-Eun, CHOI, Yeon A, JEONG, Joon, LEE, Myeong-Sok, DEA HO CHO, LIM, Jong-Seok, KEUN II KIM, YANG, Young

“…Low serum levels of adiponectin are a high risk factor for various types of cancer. Although adiponectin inhibits proliferation and metastasis of breast cancer…”
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Inhibition of osteoclast differentiation by overexpression of NDRG2 in monocytes by Kang, Kyeongah, Nam, Sorim, Kim, Bomi, Lim, Ji Hyun, Yang, Young, Lee, Myeong-Sok, Lim, Jong-Seok

“…N-Myc downstream-regulated gene 2 (NDRG2), a member of the NDRG family of differentiation-related genes, has been characterized as a regulator of dendritic…”
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Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells by Shon, Soo-Kyung, Kim, Aeyung, Kim, Ji Young, Kim, Keun Il, Yang, Young, Lim, Jong-Seok

“…In the current study, we examined the function of N-myc downstream-regulated gene 2 (NDRG2) expression in breast cancer cells, especially focusing on the role…”
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novel adipokine CTRP1 stimulates aldosterone production by Jeon, Jun Ho, Kim, Kun-yong, Kim, Jae Hyeong, Baek, Ahmi, Cho, Hyungin, Lee, Young Ho, Kim, Jong Wan, Kim, Dohee, Han, Seung Hyun, Lim, Jong-Seok, Kim, Keun Il, Yoon, Do Young, Kim, Soo-Hyun, Oh, Goo Taeg, Kim, Eunjoon, Yang, Young

“…Complement-C1q TNF-related protein 1 (CTRP1), a member of the CTRP superfamily, is expressed at high levels in adipose tissues of obese Zucker diabetic fatty…”
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Z-ajoene from Crushed Garlic Alleviates Cancer-Induced Skeletal Muscle Atrophy by Lee, Hyejin, Heo, Ji-Won, Kim, A-Reum, Kweon, Minson, Nam, Sorim, Lim, Jong-Seok, Sung, Mi-Kyung, Kim, Sung-Eun, Ryu, Jae-Ha

“…Skeletal muscle atrophy is one of the major symptoms of cancer cachexia. Garlic ( ), one of the world's most commonly used and versatile herbs, has been…”
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The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma by Lee, Jaehyouk, Jeong, Dong-Jun, Kim, Jinsun, Lee, Soonduck, Park, Jin-Hwa, Chang, Boogi, Jung, Sam-Il, Yi, Lisha, Han, Youngsoo, Yang, Young, Kim, Keun Il, Lim, Jong-Seok, Yang, Inchul, Jeon, Seob, Bae, Dong Han, Kim, Chang-Jin, Lee, Myeong-Sok

“…Klotho was originally characterized as an anti-aging gene that predisposed Klotho-deficient mice to a premature aging-like syndrome. Recently, KLOTHO was…”
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Eupatolide inhibits the TGF-β1-induced migration of breast cancer cells via downregulation of SMAD3 phosphorylation and transcriptional repression of ALK5 by Boldbaatar, Ariundavaa, Lee, Sunyi, Han, Sora, Jeong, Ae Lee, Ka, Hye In, Buyanravjikh, Sumiyasuren, Lee, Jeong Hyung, Lim, Jong-Seok, Lee, Myung Sok, Yang, Young

“…The epithelial-mesenchymal transition (EMT) is a hallmark of cancer metastasis, and the associated molecular signaling pathways are regarded as therapeutic…”
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NDRG2 suppresses cell proliferation through down‐regulation of AP‐1 activity in human colon carcinoma cells by Kim, Young Jun, Yoon, Sun Young, Kim, Jong‐Tae, Choi, Seung Cheol, Lim, Jong‐Seok, Kim, Joo Heon, Song, Eun Young, Lee, Hee Gu, Choi, Inpyoi, Kim, Jae Wha

“…Recently, the anti‐tumor activity of N‐myc downstream‐regulated gene 2 (NDRG2) was elucidated, but the molecular mechanism of how NDRG2 works as a tumor…”
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Clinical significance linked to functional defects in bone morphogenetic protein type 2 receptor, BMPR2 by Kim, Myung-Jin, Park, Seon Young, Chang, Hae Ryung, Jung, Eun Young, Munkhjargal, Anudari, Lim, Jong-Seok, Lee, Myeong-Sok, Kim, Yonghwan

“…Bone morphogenetic protein type 2 receptor (BMPR2) is one of the transforming growth factor-β (TGF-β) superfamily receptors, performing diverse roles during…”
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