Search Results - "Lim, Rebecca"

Effect of the Microenvironment on Mesenchymal Stem Cell Paracrine Signaling: Opportunities to Engineer the Therapeutic Effect by Kusuma, Gina D, Carthew, James, Lim, Rebecca, Frith, Jessica E

“…Cues from the extracellular environment, including physical stimuli, are well known to affect mesenchymal stem cell (MSC) properties in terms of proliferation…”
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Kinetic analysis of T4 polynucleotide kinase via isothermal titration calorimetry by Lim, Rebecca C., Gary, Ronald K.

“…T4 polynucleotide kinase (T4 PNK) phosphorylates the 5′-terminus of DNA and RNA substrates. It is widely used in molecular biology. Single nucleotides can…”
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Anatomical and physiological development of the human inner ear by Lim, Rebecca, Brichta, Alan M.

“…We describe the development of the human inner ear with the invagination of the otic vesicle at 4 weeks gestation (WG), the growth of the semicircular canals…”
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A Universal CAR-NK Cell Targeting Various Epitopes of HIV‑1 gp160 by Lim, Rebecca M, Rong, Liang, Zhen, Anjie, Xie, Jianming

“…Engineering T cells and natural killer (NK) cells with anti-HIV chimeric antigen receptors (CAR) has emerged as a promising strategy to eradicate HIV-infected…”
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Kinetic Analysis of T4 Polynucleotide Kinase via Isothermal Titration Calorimetry by Lim, Rebecca C., Gary, Ronald K.

“…Isothermal titration calorimetry (ITC) measures the heat absorbed or released from biochemical processes. Although the primary application of ITC has been in…”
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Current concepts and new trends in management of isolated triangular fibrocartilage complex injuries by Lim, Rebecca Q. R., Lim, Lincoln J. R., Atzei, Andrea, Liu, Bo

“…The triangular fibrocartilaginous complex is made of multiple components, of which the palmar and dorsal radioulnar ligaments play an important role in distal…”
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Organic Bioelectronics: Materials and Biocompatibility by Feron, Krishna, Lim, Rebecca, Sherwood, Connor, Keynes, Angela, Brichta, Alan, Dastoor, Paul C

“…Organic electronic materials have been considered for a wide-range of technological applications. More recently these organic (semi)conductors (encompassing…”
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HtrA4 may play a major role in inhibiting endothelial repair in pregnancy complication preeclampsia by Wang, Yao, Lim, Rebecca, Nie, Guiying

“…Preeclampsia (PE) is a life-threatening complication of human pregnancy with no effective treatment other than premature delivery. It is hallmarked by systemic…”
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Site-Specific Dinitrophenylation of Single-Chain Antibody Fragments for Redirecting a Universal CAR-T Cell against Cancer Antigens by Rong, Liang, Lim, Rebecca M., Yin, Xiaosuo, Tan, Liyao, Yang, Jae H., Xie, Jianming

“…[Display omitted] •DNP-conjugated antibodies redirect anti-DNP CAR-T cells against various antigens.•The scFv antibodies modified with DNP at the GS-linker are…”
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Polycyclic aromatic hydrocarbons regulate the pigmentation pathway and induce DNA damage responses in keratinocytes, a process driven by systemic immunity by Chan, Tze Khee, Bramono, Diah, Bourokba, Nasrine, Krishna, Vedula, Wang, Siew Tein, Neo, Boon Hoe, Lim, Rebecca Y.X., Kim, Hyoju, Misra, Namita, Lim, Shawn, Betts, Richard J.

“…•BaP regulates pigmentation via activation of systemic immunity and the AhR pathway.•BaP-activated PBMC induce DNA damage and POMC secretion in…”
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To Protect and to Preserve: Novel Preservation Strategies for Extracellular Vesicles by Kusuma, Gina D, Barabadi, Mehri, Tan, Jean L, Morton, David A V, Frith, Jessica E, Lim, Rebecca

“…Extracellular vesicles (EVs)-based therapeutics are based on the premise that EVs shed by stem cells exert similar therapeutic effects and these have been…”
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HtrA4 is up-regulated during trophoblast syncytialization and BeWo cells fail to syncytialize without HtrA4 by Mansilla, Mary, Wang, Yao, Lim, Rebecca, Palmer, Kirsten, Nie, Guiying

“…The outer layer of the human placenta comprises syncytiotrophoblast, which forms through fusion of cytotrophoblasts (syncytialization), and plays a critical…”
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A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis by Guo, Pengfei, Lim, Rebecca C, Rajawasam, Keshari, Trinh, Tiffany, Sun, Hong, Zhang, Hui

“…The Polycomb Repressive Complex 2 (PRC2) methylates H3K27 to regulate development and cell fate by transcriptional silencing. Alteration of PRC2 is associated…”
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Human amnion epithelial cells mediate lung repair by directly modulating macrophage recruitment and polarization by Tan, Jean L, Chan, Siow Teng, Wallace, Euan M, Lim, Rebecca

“…Human amnion epithelial cells (hAECs) have been shown to modulate inflammation and restore normal lung structure and respiratory function following bleomycin…”
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Amnion Epithelial Cell‐Derived Exosomes Restrict Lung Injury and Enhance Endogenous Lung Repair by Tan, Jean L., Lau, Sin N., Leaw, Bryan, Nguyen, Hong P. T., Salamonsen, Lois A., Saad, Mohamed I., Chan, Siow T., Zhu, Dandan, Krause, Mirja, Kim, Carla, Sievert, William, Wallace, Euan M., Lim, Rebecca

“…Idiopathic pulmonary fibrosis (IPF) is characterized by chronic inflammation, severe scarring, and stem cell senescence. Stem cell‐based therapies modulate…”
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First‐In‐Human Administration of Allogeneic Amnion Cells in Premature Infants With Bronchopulmonary Dysplasia: A Safety Study by Lim, Rebecca, Malhotra, Atul, Tan, Jean, Chan, Siow Teng, Lau, Sinnee, Zhu, Dandan, Mockler, Joanne C., Wallace, Euan M.

“…Bronchopulmonary dysplasia (BPD) is a chronic lung disease that mainly affects premature babies who require ventilator support. The pathogenesis of BPD is…”
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Two‐year outcomes of infants enrolled in the first‐in‐human study of amnion cells for bronchopulmonary dysplasia by Malhotra, Atul, Lim, Rebecca, Mockler, Joanne C., Wallace, Euan M.

“…We previously reported on the immediate safety and neonatal outcomes of six premature infants with severe bronchopulmonary dysplasia (BPD) who were…”
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Serelaxin enhances the therapeutic effects of human amnion epithelial cell‐derived exosomes in experimental models of lung disease by Royce, Simon G., Patel, Krupesh P., Mao, WeiYi, Zhu, Dandan, Lim, Rebecca, Samuel, Chrishan S.

“…Background and Purpose There is growing interest in stem cell‐derived exosomes for their therapeutic and regenerative benefits given their manufacturing and…”
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International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 by Börger, Verena, Weiss, Daniel J., Anderson, Johnathon D., Borràs, Francesc E., Bussolati, Benedetta, Carter, David R.F., Dominici, Massimo, Falcón-Pérez, Juan M., Gimona, Mario, Hill, Andrew F., Hoffman, Andrew M., de Kleijn, Dominique, Levine, Bruce L., Lim, Rebecca, Lötvall, Jan, Mitsialis, S. Alex, Monguió-Tortajada, Marta, Muraca, Maurizio, Nieuwland, Rienk, Nowocin, Anna, O'Driscoll, Lorraine, Ortiz, Luis A., Phinney, Donald G, Reischl, Ilona, Rohde, Eva, Sanzenbacher, Ralf, Théry, Clotilde, Toh, Wei Seong, Witwer, Kenneth W., Lim, Sai Kiang, Giebel, Bernd

“…STATEMENT: The International Society for Cellular and Gene Therapies (ISCT) and the International Society for Extracellular Vesicles (ISEV) recognize the…”
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Fourier-Transform Infra-Red Microspectroscopy Can Accurately Diagnose Colitis and Assess Severity of Inflammation by Keung, Charlotte, Heraud, Philip, Kuk, Nathan, Lim, Rebecca, Sievert, William, Moore, Gregory, Wood, Bayden

“…The diagnosis and management of inflammatory bowel disease relies on histological assessment, which is costly, subjective, and lacks utility for point-of-care…”
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