Search Results - "Lim, Kian H."

Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point by Darman, Rachel B., Seiler, Michael, Agrawal, Anant A., Lim, Kian H., Peng, Shouyong, Aird, Daniel, Bailey, Suzanna L., Bhavsar, Erica B., Chan, Betty, Colla, Simona, Corson, Laura, Feala, Jacob, Fekkes, Peter, Ichikawa, Kana, Keaney, Gregg F., Lee, Linda, Kumar, Pavan, Kunii, Kaiko, MacKenzie, Crystal, Matijevic, Mark, Mizui, Yoshiharu, Myint, Khin, Park, Eun Sun, Puyang, Xiaoling, Selvaraj, Anand, Thomas, Michael P., Tsai, Jennifer, Wang, John Y., Warmuth, Markus, Yang, Hui, Zhu, Ping, Garcia-Manero, Guillermo, Furman, Richard R., Yu, Lihua, Smith, Peter G., Buonamici, Silvia

“…Recurrent mutations in the spliceosome are observed in several human cancers, but their functional and therapeutic significance remains elusive. SF3B1, the…”
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Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA by Kaseb, Ahmed O, Sánchez, Nora S, Sen, Shiraj, Kelley, Robin K, Tan, Benjamin, Bocobo, Andrea G, Lim, Kian H, Abdel-Wahab, Reham, Uemura, Marc, Pestana, Roberto Carmagnani, Qiao, Wei, Xiao, Lianchun, Morris, Jeffrey, Amin, Hesham M, Hassan, Manal M, Rashid, Asif, Banks, Kimberly C, Lanman, Richard B, Talasaz, AmirAli, Mills-Shaw, Kenna R, George, Bhawana, Haque, Abedul, Raghav, Kanwal P S, Wolff, Robert A, Yao, James C, Meric-Bernstam, Funda, Ikeda, Sadakatsu, Kurzrock, Razelle

“…Molecular profiling has been used to select patients for targeted therapy and determine prognosis. Noninvasive strategies are critical to hepatocellular…”
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The clonal evolution of metastatic colorectal cancer by Dang, Ha X, Krasnick, Bradley A, White, Brian S, Grossman, Julie G, Strand, Matthew S, Zhang, Jin, Cabanski, Christopher R, Miller, Christopher A, Fulton, Robert S, Goedegebuure, S Peter, Fronick, Catrina C, Griffith, Malachi, Larson, David E, Goetz, Brian D, Walker, Jason R, Hawkins, William G, Strasberg, Steven M, Linehan, David C, Lim, Kian H, Lockhart, A Craig, Mardis, Elaine R, Wilson, Richard K, Ley, Timothy J, Maher, Christopher A, Fields, Ryan C

“…Tumor heterogeneity and evolution drive treatment resistance in metastatic colorectal cancer (mCRC). Patient-derived xenografts (PDXs) can model mCRC biology;…”
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Abstract 4109: Clonal evolution of metastatic colorectal cancer by Dang, Ha X., Grossman, Julie, White, Brian S., Strand, Matthew, Larson, David E., Walker, Jason, Pittman, Elizabeth, Fleming, Timothy, Goedegebuure, Peter S., Fulton, Robert S., Miller, Christopher A., Griffith, Malachi, Lim, Kian H., Ley, Timothy J., Wilson, Richard K., Mardis, Elaine R., Lockhart, A.Craig, Fields, Ryan C., Maher, Christopher A.

“…Abstract Introduction: Death from colorectal cancer (CRC) occurs via sequelae of metastases. Our lack of understanding of the mechanisms driving metastatic…”
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