Search Results - "Lim, Kheng B"

Phosphopeptides enrichment using on-line two-dimensional strong cation exchange followed by reversed-phase liquid chromatography/mass spectrometry by Lim, Kheng B., Kassel, Daniel B.

“…We have developed a method to isolate and enhance the detection of phosphopeptides using liquid chromatography (LC)/mass spectrometry on a tryptic-digested…”
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Lipid A Acylation and Bacterial Resistance against Vertebrate Antimicrobial Peptides by Guo, Lin, Lim, Kheng B, Poduje, Cristina M, Daniel, Morad, Gunn, John S, Hackett, Murray, Miller, Samuel I

“…The Salmonellae PhoP-PhoQ virulence regulators induce resistance to host cationic antimicrobial peptides (CAMP) after infection of vertebrate tissues, and Mg…”
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Structure of a c-Kit Product Complex Reveals the Basis for Kinase Transactivation by Mol, Clifford D., Lim, Kheng B., Sridhar, Vandana, Zou, Hua, Chien, Ellen Y.T., Sang, Bi-Ching, Nowakowski, Jacek, Kassel, Daniel B., Cronin, Ciarán N., McRee, Duncan E.

“…The c-Kit proto-oncogene is a receptor protein-tyrosine kinase associated with several highly malignant human cancers. Upon binding its ligand, stem cell…”
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PmrA–PmrB‐regulated genes necessary for 4‐aminoarabinose lipid A modification and polymyxin resistance by Gunn, John S., Lim, Kheng B., Krueger, Jackie, Kim, Kevin, Guo, Lin, Hackett, Murray, Miller, Samuel I.

“…Antimicrobial peptides are distributed throughout the animal kingdom and are a key component of innate immunity. Salmonella typhimurium regulates mechanisms of…”
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Production of selenomethionyl‐derivatized proteins in baculovirus‐infected insect cells by Cronin, Ciarán N., Lim, Kheng B., Rogers, Joe

“…A protocol is described for the production of both intracellularly expressed and secreted selenomethionyl‐derivatized recombinant proteins in…”
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A novel class of microbial phosphocholine‐specific phospholipases C by Stonehouse, Martin J., Cota‐Gomez, Adela, Parker, Sarah K., Martin, Wesley E., Hankin, Joseph A., Murphy, Robert C., Chen, Weibin, Lim, Kheng B., Hackett, Murray, Vasil, Adriana I., Vasil, Michael L.

“…Summary In this report we describe the 1500‐fold purification and characterization of the haemolytic phospholipase C (PLC) of Pseudomonas aeruginosa, the…”
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Specific Lipopolysaccharide Found in Cystic Fibrosis Airway Pseudomonas aeruginosa by Ernst, Robert K., Yi, Eugene C., Guo, Lin, Lim, Kheng B., Burns, Jane L., Hackett, Murray, Miller, Samuel I.

“…Cystic fibrosis (CF) patients develop chronic airway infections with Pseudomonas aeruginosa (PA). Pseudomonas aeruginosa synthesized lipopolysaccharide (LPS)…”
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Development of a high-throughput online solid-phase extraction/tandem mass spectrometry method for cytochrome P450 inhibition screening by Lim, Kheng B, Ozbal, Can C, Kassel, Daniel B

“…A high-throughput online solid-phase extraction/tandem mass spectrometry (online SPE/MS/MS) system has been developed to support rapid evaluation of drug…”
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Regulation of Lipid A Modifications by Salmonella typhimurium Virulence Genes phoP-phoQ by Guo, Lin, Lim, Kheng B., Gunn, John S., Bainbridge, Brian, Darveau, Richard P., Hackett, Murray, Miller, Samuel I.

“…Bacterial pathogenesis requires proteins that sense host microenvironments and respond by regulating virulence gene transcription. For Salmonellae, one such…”
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High-throughput mass spectrometric cytochrome P450 inhibition screening by Lim, Kheng B, Ozbal, Can C, Kassel, Daniel B

“…We describe here a high-throughput assay to support rapid evaluation of drug discovery compounds for possible drug-drug interaction (DDI). Each compound is…”
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Initial studies of a new approach to the design and use of enzyme-based reactor/sensor systems: amperometric system for glucose by Uhegbu, Christopher E, Lim, Kheng B, Pardue, Harry L

“…This paper describes the development and evaluation of a new approach to the design and use of enzyme-based reactor/sensor systems (so-called "enzyme…”
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Escherichia coli α-Hemolysin (HlyA) Is Heterogeneously Acylated in Vivo with 14-, 15-, and 17-Carbon Fatty Acids by Lim, Kheng B., Walker, Carthene R. Bazemore, Guo, Lin, Pellett, Shahaireen, Shabanowitz, Jeffrey, Hunt, Donald F., Hewlett, Erik L., Ludwig, Albrecht, Goebel, Werner, Welch, Rodney A., Hackett, Murray

“…α-Hemolysin (HlyA) is a secreted protein virulence factor observed in certain uropathogenic strains ofEscherichia coli. The active, mature form of HlyA is…”
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Escherichia coli α-Hemolysin (HlyA) Is Heterogeneously Acylated in Vivo with 14-, 15-, and 17-Carbon Fatty Acids by Kheng B. Lim, Carthene R. Bazemore Walker, Lin Guo, Shahaireen Pellett, Jeffrey Shabanowitz, Donald F. Hunt, Erik L. Hewlett, Albrecht Ludwig, Werner Goebel, Rodney A. Welch, Murray Hackett

“…α-Hemolysin (HlyA) is a secreted protein virulence factor observed in certain uropathogenic strains of Escherichia coli . The active, mature form of HlyA is…”
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Stability Enhancement for Peptide Analysis by Electrospray Using the Triple Quadrupole Mass Spectrometer by Wang, Houle, Lim, Kheng B., Lawrence, Ross F., Howald, William N., Taylor, J.Alex, Ericsson, Lowell H., Walsh, Kenneth A., Hackett, Murray

“…Electrospray ionization sources, used with triple quadrupole mass spectrometers from PE/Sciex (API III+), Micromass (Quattro II), and Finnigan (TSQ 7000), were…”
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Error-compensating kinetic method for enzymatic determination of DNAs by Lim, K B, Pardue, H L

“…We describe the adaptation and evaluation of an error-compensating method for kinetic determinations of deoxyribonucleic acids (DNAs). The DNA is first reacted…”
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