Search Results - "Lim, Joong In"

Design, Synthesis, and Biological Evaluation of Novel Constrained meta-Substituted Phenyl Propanoic Acids as Peroxisome Proliferator-Activated Receptor α and γ Dual Agonists by Suh, Young-Ger, Kim, Nam-Jung, Koo, Bon-Woong, Lee, Kwang-Ok, Moon, Sung-Hyun, Shin, Dong-Hyung, Jung, Jong-Wha, Paek, Seung-Mann, Chang, Dong-Jo, Li, Funan, Kang, Hyun-Jin, Le, Tuong Vy Thi, Chae, Yu Na, Shin, Chang Yell, Kim, Mi-Kyung, Lim, Joong In, Ryu, Jae-Sang, Park, Hyun-Ju

“…In an effort to develop dual PPARα/γ activators with improved therapeutic efficacy, a series of diaryl α-ethoxy propanoic acid compounds comprising two aryl…”
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PAR-1622 is a selective peroxisome proliferator-activated receptor γ partial activator with preserved antidiabetic efficacy and broader safety profile for fluid retention by Kim, Mi-Kyung, Chae, Yu Na, Kim, Hae Sun, Choi, Song-hyen, Son, Moon Ho, Kim, Soon Hoe, Kim, Jin Kwan, Moon, Ho Sang, Park, Sang Kuk, Shin, Young Ah, Kim, Jae Gyu, Lee, Chun Ho, Lim, Joong In, Shin, Chang Yell

“…Peroxisome proliferator-activated receptor (PPAR) γ is known to be a key regulator of insulin resistance. PAR-1622 is a novel small molecule compound…”
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Quantification of a novel PPARγ partial agonist (S)-2-ethoxy-3-(4-{3-methyl-5-[4-(3-methyl-isoxazol-5-yl)-phenyl]thiophen-2-ylmethoxy}-phenyl)-propionic acid (PAM-1616) in rat plasma using liquid chromatography-tandem mass spectrometry by Chae, Hye Won, Jung, Haehum, Kim, Eun Jung, Shim, Hyun Joo, Lim, Joong In, Ji, Hye Young, Lee, Hye Suk

“…( S )-2-ethoxy-3-(4-{3-methyl-5-[4-(3-methyl-isoxazol-5-yl)-phenyl]thiophen-2-ylmethoxy}-phenyl)-propionic acid (PAM-1616) is a novel peroxisome…”
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Liquid chromatography-tandem mass spectrometry of a new PPARα/γ dual agonist PAR-5359 in rat plasma by Kim, Dong Kyun, Park, Eun Jeong, Jeong, Ji Hyun, Jeon, Sun Ho, Kim, Eun Jung, Shim, Hyun Joo, Lim, Joong In, Lee, Hye Suk

“…PAR-5359, 3-(4-{2-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-ethoxy}-phenyl)-2-ethoxypropionic acid, is a well-balanced PPARα/γ dual agonist with the…”
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Anti-Diabetic Effects of DA-11004, a Synthetic IDPc Inhibitor in High Fat High Sucrose Diet-Fed C57BL/6J Mice by Shin, Chang-Yell, Jung, Mi-Young, Lee, In-Ki, Son, Mi-Won, Kim, Dong-Sung, Lim, Joong-In, Kim, Soon-Hoe, Yoo, Moo-Hi, Huh, Tae-Lin, Sohn, Young-Taek, Kim, Won-Bae

“…DA-11004 is a synthetic, potent NADP-dependent isocitrate dehydrogenase (IDPc) inhibitor where $IC_{50}$ for IDPc is 1.49 $\mu$M. The purpose of this study was…”
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PAM-1616, a selective peroxisome proliferator-activated receptor γ modulator with preserved anti-diabetic efficacy and reduced adverse effects by Kim, Mi-Kyung, Chae, Yu Na, Choi, Song-hyen, Moon, Ho Sang, Son, Moon-Ho, Bae, Myung-Ho, Choi, Hyun-ho, Hur, Youn, Kim, Eunkyung, Park, Yoo Hoi, Park, Chan Sun, Kim, Jae Gyu, Lim, Joong In, Shin, Chang Yell

“…Peroxisome proliferator-activated receptor (PPAR) γ is known to be a key regulator of insulin resistance. PAM-1616 is a novel, non-thiazolidinedione small…”
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Design, synthesis, and structure–activity relationship of carbamate-tethered aryl propanoic acids as novel PPARα/γ dual agonists by Kim, Nam-Jung, Lee, Kwang-Ok, Koo, Bon-Woong, Li, Funan, Yoo, Ja-Kyung, Park, Hyun-Ju, Min, Kyung-Hoon, Lim, Joong In, Kim, Mi Kyung, Kim, Jin-Kwan, Suh, Young-Ger

“…We have developed a new class of PPARα/γ dual agonists, which show excellent agonistic activity in PPARα/γ transactivation assay. In particular, ( R)- 9d was…”
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Anti-diabetic effects of DA-11004, a synthetic IDPc inhibitor in high fat high sucrose diet-fed C57BL/6J mice by Shin, Chang Yell, Jung, Mi Young, Lee, In Ki, Son, Miwon, Kim, Dong Sung, Lim, Joong In, Kim, Soon Hoe, Yoo, Moohi, Huh, Tae Lin, Sohn, Young Taek, Kim, Won Bae

“…DA-11004 is a synthetic, potent NADP-dependent isocitrate dehydrogenase (IDPc) inhibitor where IC50 for IDPc is 1.49 microM. The purpose of this study was to…”
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An Efficient Process of Ondansetron Synthesis by Yoo Kim, Moohi, Jho Lim, Geun, In Lim, Joong, Sung Kim, Dong, Yon Kim, Ik, Sung Yang, Jae

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PAR-5359, a well-balanced PPARα/γ dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo by Kim, Mi-Kyung, Chae, Yu Na, Son, Moon Ho, Kim, Soon Hoe, Kim, Jin Kwan, Moon, Ho Sang, Park, Chan Sun, Bae, Myung-Ho, Kim, Eunkyung, Han, Taedong, Choi, Hyun-ho, Shin, Young Ah, Ahn, Byung-Nak, Lee, Chun Ho, Lim, Joong In, Shin, Chang Yell

“…Peroxisome proliferator-activated receptor (PPAR) α and γ are key regulators of lipid homeostasis and insulin resistance. In this study, we characterize the…”
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Design, synthesis, and evaluation of novel aryl-tetrahydropyridine PPARα/γ dual agonists by Kim, Eunkyung, Park, Chan Sun, Han, Taedong, Bae, Myung-Ho, Chong, Wonee, Lee, Choong Hyun, Shin, Young Ah, Ahn, Byung-Nak, Kim, Mi Kyung, Shin, Chang Yell, Son, Moon Ho, Kim, Jin Kwan, Moon, Ho Sang, Shim, Hyun Joo, Kim, Eun Jung, Kim, Soon Hoe, Lim, Joong In, Lee, Chun Ho

“…The synthesis of the potent PPARα/γ dual agonist (S)-5b (EC 50 = 1.73/0.64 μM (α/γ)) is reported. Aryl-tetrahydropyridine derivatives were prepared and their…”
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Liquid chromatography-tandem mass spectrometry of a new PPARalpha/gamma dual agonist PAR-5359 in rat plasma by Kim, Dong Kyun, Park, Eun Jeong, Jeong, Ji Hyun, Jeon, Sun Ho, Kim, Eun Jung, Shim, Hyun Joo, Lim, Joong In, Lee, Hye Suk

“…PAR-5359, 3-(4-{2-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-ethoxy}-phenyl)-2-ethoxypropionic acid, is a well-balanced PPARalpha/gamma dual agonist…”
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PAR-5359, a well-balanced PPARalpha/gamma dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo by Kim, Mi-Kyung, Chae, Yu Na, Son, Moon Ho, Kim, Soon Hoe, Kim, Jin Kwan, Moon, Ho Sang, Park, Chan Sun, Bae, Myung-Ho, Kim, Eunkyung, Han, Taedong, Choi, Hyun-Ho, Shin, Young Ah, Ahn, Byung-Nak, Lee, Chun Ho, Lim, Joong In, Shin, Chang Yell

“…Peroxisome proliferator-activated receptor (PPAR) alpha and gamma are key regulators of lipid homeostasis and insulin resistance. In this study, we…”
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Design, synthesis, and structure-activity relationship of carbamate-tethered aryl propanoic acids as novel PPARalpha/gamma dual agonists by Kim, Nam-Jung, Lee, Kwang-Ok, Koo, Bon-Woong, Li, Funan, Yoo, Ja-Kyung, Park, Hyun-Ju, Min, Kyung-Hoon, Lim, Joong In, Kim, Mi Kyung, Kim, Jin-Kwan, Suh, Young-Ger

“…We have developed a new class of PPARalpha/gamma dual agonists, which show excellent agonistic activity in PPARalpha/gamma transactivation assay. In…”
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Design, synthesis, and evaluation of novel aryl-tetrahydropyridine PPARalpha/gamma dual agonists by Kim, Eunkyung, Park, Chan Sun, Han, Taedong, Bae, Myung-Ho, Chong, Wonee, Lee, Choong Hyun, Shin, Young Ah, Ahn, Byung-Nak, Kim, Mi Kyung, Shin, Chang Yell, Son, Moon Ho, Kim, Jin Kwan, Moon, Ho Sang, Shim, Hyun Joo, Kim, Eun Jung, Kim, Soon Hoe, Lim, Joong In, Lee, Chun Ho

“…Aryl-tetrahydropyridine derivatives were prepared and their PPARalpha/gamma dual agonistic activities were evaluated. Among them, compound (S)-5b was…”
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A synthetic approach to (+)-brefeldin A by Kim, Deukjoon, Lim, Joong In

“…A unique 12-step scheme for the stereoselective synthesis of (+)-brefeldin A intermediate 2 starting from ethyl O-benzyl (S)-lactate ( 3) has been…”
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PAR-5359, a well-balanced PPARa/γ dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo by KIM, Mi-Kyung, YU NA CHAE, CHOI, Hyun-Ho, YOUNG AH SHIN, AHN, Byung-Nak, CHUN HO LEE, JOONG IN LIM, CHANG YELL SHIN, MOON HO SON, SOON HOE KIM, JIN KWAN KIM, HO SANG MOON, CHAN SUN PARK, BAE, Myung-Ho, KIM, Eunkyung, HAN, Taedong

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Design, synthesis, and evaluation of novel aryl-tetrahydropyridine PPARa/y dual agonists by KIM, Eunkyung, PARK, Chan Sun, MOON HO SON, JIN KWAN KIM, HO SANG MOON, HYUN JOO SHIM, EUN JUNG KIM, SOON HOE KIM, JOONG IN LIM, CHUN HO LEE, HAN, Taedong, BAE, Myung-Ho, CHONG, Wonee, CHOONG HYUN LEE, YOUNG AH SHIN, AHN, Byung-Nak, MI KYUNG KIM, CHANG YELL SHIN

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Finite element analysis of maxillary incisor displacement during en-masse retraction according to orthodontic mini-implant position by Song, Jae-Won, Lim, Joong-Ki, Lee, Kee-Joon, Sung, Sang-Jin, Chun, Youn-Sic, Mo, Sung-Seo

“…Objective: Orthodontic mini-implants (OMI) generate various horizontal and vertical force vectors and moments according to their insertion positions. This…”
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A Technology of Information Data Fusion between Radar and ELINT System by Lim, Joong-Soo

“…This paper presents a technology of information data fusion between radar and ELINT electronic intelligence system. adar get the information of the range,…”
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