Search Results - "Lim, Johan"
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1
Enhanced construction of gene regulatory networks using hub gene information
Published in BMC bioinformatics (23-03-2017)“…Gene regulatory networks reveal how genes work together to carry out their biological functions. Reconstructions of gene networks from gene expression data…”
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2
Estimation of the case fatality rate based on stratification for the COVID-19 outbreak
Published in PloS one (22-02-2021)“…This work is motivated by the recent worldwide pandemic of the novel coronavirus disease (COVID-19). When an epidemiological disease is prevalent, estimating…”
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3
Goodness-of-fit testing for meta-analysis of rare binary events
Published in Scientific reports (18-10-2023)“…Random-effects (RE) meta-analysis is a crucial approach for combining results from multiple independent studies that exhibit heterogeneity. Recently, two…”
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4
Condition-number-regularized covariance estimation
Published in Journal of the Royal Statistical Society. Series B, Statistical methodology (01-06-2013)“…Estimation of high dimensional covariance matrices is known to be a difficult problem, has many applications and is of current interest to the larger…”
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Efficacy and safety of intravenous and subcutaneous immunoglobulin therapy in idiopathic inflammatory myopathy: A systematic review and meta-analysis
Published in Autoimmunity reviews (01-02-2022)“…To perform a systematic review and meta-analysis on the efficacy and safety of intravenous (IVIg) and subcutaneous (SCIg) immunoglobulin (Ig) therapy in the…”
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Metabolic response induced by parasitic plant-fungus interactions hinder amino sugar and nucleotide sugar metabolism in the host
Published in Scientific reports (28-11-2016)“…Infestation by the biotrophic pathogen Gymnosporangium asiaticum can be devastating for plant of the family Rosaceae. However, the phytopathology of this…”
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7
Lipidome profile predictive of disease evolution and activity in rheumatoid arthritis
Published in Experimental & molecular medicine (01-02-2022)“…Lipid mediators are crucial for the pathogenesis of rheumatoid arthritis (RA); however, global analyses have not been undertaken to systematically define the…”
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Intravenous immunoglobulins as first-line treatment in idiopathic inflammatory myopathies: a pilot study
Published in Rheumatology (Oxford, England) (06-04-2021)“…Abstract Objectives We explored efficacy and safety of IVIg as first-line treatment in patients with an idiopathic inflammatory myopathy. Methods In this…”
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High-Throughput Omics and Statistical Learning Integration for the Discovery and Validation of Novel Diagnostic Signatures in Colorectal Cancer
Published in International journal of molecular sciences (12-01-2019)“…The advancement of bioinformatics and machine learning has facilitated the discovery and validation of omics-based biomarkers. This study employed a novel…”
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10
Image Segmentation Using Hidden Markov Gauss Mixture Models
Published in IEEE transactions on image processing (01-07-2007)“…Image segmentation is an important tool in image processing and can serve as an efficient front end to sophisticated algorithms and thereby simplify subsequent…”
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11
High-dimensional Markowitz portfolio optimization problem: empirical comparison of covariance matrix estimators
Published in Journal of statistical computation and simulation (03-05-2019)“…We compare the performance of recently developed regularized covariance matrix estimators for Markowitz's portfolio optimization and of the minimum variance…”
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12
Research Quality-Based Multivariate Modeling for Comparison of the Pharmacological Effects of Black and Red Ginseng
Published in Nutrients (26-08-2020)“…Black ginseng has various pharmacological activities, but only few studies have compared its pharmacological effects with those of red ginseng. We conducted an…”
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13
Determination of coffee origins by integrated metabolomic approach of combining multiple analytical data
Published in Food chemistry (15-08-2010)“…The flavor and taste of coffee are the most important criteria for evaluating its quality and they are influenced by environmental as well as genetic factors…”
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14
TCRβ clones in muscle tissue share structural features in patients with idiopathic inflammatory myopathy and are associated with disease activity
Published in Frontiers in immunology (10-01-2024)“…To characterize the T cell receptor (TCRβ) repertoire in peripheral blood and muscle tissues of treatment naïve patients with newly diagnosed idiopathic…”
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15
Seronegative patients form a distinctive subgroup of immune-mediated necrotizing myopathy
Published in Neurology : neuroimmunology & neuroinflammation (01-01-2019)“…OBJECTIVESTo investigate the characteristics of different clinico-serologic subgroups of immune-mediated necrotizing myopathy (IMNM). METHODSWe retrospectively…”
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Classification of spectral data using fused lasso logistic regression
Published in Chemometrics and intelligent laboratory systems (01-03-2015)Get full text
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17
Meta-Analysis of Tumor Stem-Like Breast Cancer Cells Using Gene Set and Network Analysis
Published in PloS one (12-02-2016)“…Generally, cancer stem cells have epithelial-to-mesenchymal-transition characteristics and other aggressive properties that cause metastasis. However, there…”
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18
Application of fused lasso logistic regression to the study of corpus callosum thickness in early Alzheimer's disease
Published in Journal of neuroscience methods (15-01-2014)“…•Development of an algorithm for fused lasso logistic regression (FLLR) model.•We applied FLLR to classify Alzheimer disease (AD) subjects from normal…”
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Metabolic and Cardiovascular Benefits of Apple and Apple-Derived Products: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Published in Frontiers in nutrition (Lausanne) (05-04-2022)“…Quantitative evidence of the metabolic and cardiovascular effects of apples ( ) is lacking in interventional studies. This study aimed to summarize the…”
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20
Frequencies and clinical associations of myositis-related antibodies in The Netherlands: A one-year survey of all Dutch patients
Published in Journal of translational autoimmunity (Online) (01-12-2019)“…Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of connective tissue diseases, collectively known as myositis. Diagnosis of IIM is…”
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