Search Results - "Lim, Hyun Kook"
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Differences in cortical structure between cognitively normal East Asian and Caucasian older adults: a surface-based morphometry study
Published in Scientific reports (01-12-2020)“…There is a growing literature on the impact of ethnicity on brain structure and function. Despite the regional heterogeneity in age-related changes and…”
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Apathy and white matter integrity in Alzheimer's disease: a whole brain analysis with tract-based spatial statistics
Published in PloS one (03-01-2013)“…The aim of this study was to investigate the microstructural alterations of white matter (WM) in Alzheimer's disease (AD) patients with apathy and to observe…”
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Automated hippocampal subfields segmentation in late life depression
Published in Journal of affective disorders (20-12-2012)“…Abstract Although a few automated hippocampal subfields segmentation methods have been developed, there has been no in vivo Magnetic Resonance Imaging (MRI)…”
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Impact of Transcranial Direct Current Stimulation on Cognitive Function, Brain Functional Segregation, and Integration in Patients with Mild Cognitive Impairment According to Amyloid-Beta Deposition and APOE ε4-Allele: A Pilot Study
Published in Brain sciences (10-06-2021)“…Anodal transcranial direct current stimulation (anodal-tDCS) is known to improve cognition and normalize abnormal network configuration during resting-state…”
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The prevalence of psychiatric comorbidities in adult ADHD compared with non-ADHD populations: A systematic literature review
Published in PloS one (04-11-2022)“…Comorbid psychiatric disorders in adults with ADHD are important because these comorbidities might complicate the diagnosis of ADHD and also worsen the…”
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Clinical Evidence of Antidepressant Effects of Insulin and Anti-Hyperglycemic Agents and Implications for the Pathophysiology of Depression-A Literature Review
Published in International journal of molecular sciences (22-09-2020)“…Close connections between depression and type 2 diabetes (T2DM) have been suggested by many epidemiological and experimental studies. Disturbances in insulin…”
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Regional amyloid burden and intrinsic connectivity networks in cognitively normal elderly subjects
Published in Brain (London, England : 1878) (01-12-2014)“…Although previous studies demonstrated decreased functional connectivity in the default mode network in the cognitively normal older adults with amyloid…”
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Adult Guardianship in Korea: What Do Psychiatrists Need to Know?
Published in Psychiatry investigation (01-10-2018)“…KCI Citation Count: 0…”
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Orexin and Alzheimer’s Disease: A New Perspective
Published in Psychiatry investigation (01-07-2020)“…Orexin’s role in human cognition has recently been emphasized and emerging evidences indicate its close relationship with Alzheimer’s disease (AD). This review…”
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Evaluating brain volume segmentation accuracy and reliability of FreeSurfer and Neurophet AQUA at variations in MRI magnetic field strengths
Published in Scientific reports (18-10-2024)“…We aimed to compare the accuracy and reliability of two segmentation tools for magnetic resonance (MR) volumetry (FreeSurfer and Neurophet AQUA) at two…”
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Effects of transcranial direct current stimulation on cognition in MCI with Alzheimer's disease risk factors using Bayesian analysis
Published in Scientific reports (13-08-2024)“…Despite the growing interest in precision medicine-based therapies for Alzheimer's disease (AD), little research has been conducted on how individual AD risk…”
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Late-life depression, subjective cognitive decline, and their additive risk in incidence of dementia: A nationwide longitudinal study
Published in PloS one (14-07-2021)“…Late-life depression and subjective cognitive decline (SCD) are significant risk factors for dementia. However, studies with a large sample size are needed to…”
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A Comparative Analysis of Two Automated Quantification Methods for Regional Cerebral Amyloid Retention: PET-Only and PET-and-MRI-Based Methods
Published in International journal of molecular sciences (01-07-2024)“…Accurate quantification of amyloid positron emission tomography (PET) is essential for early detection of and intervention in Alzheimer's disease (AD) but…”
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Cognitive Normal Older Adults with APOE-2 Allele Show a Distinctive Functional Connectivity Pattern in Response to Cerebral Aβ Deposition
Published in International journal of molecular sciences (01-07-2023)“…The ε2 allele of apolipoprotein E (ε2) has neuroprotective effects against beta-amyloid (Aβ) pathology in Alzheimer's disease (AD). However, its impact on the…”
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A multimodal machine learning model for predicting dementia conversion in Alzheimer’s disease
Published in Scientific reports (29-05-2024)“…Alzheimer’s disease (AD) accounts for 60–70% of the population with dementia. Mild cognitive impairment (MCI) is a diagnostic entity defined as an intermediate…”
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Role of Sleep Disturbance in the Trajectory of Alzheimer's Disease
Published in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology (31-05-2017)“…Sleep disturbances such as insomnia, hypersomnia, and circadian rhythm disturbance are common in normal elderly and Alzheimer's disease (AD) patients. To date,…”
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Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer’s disease
Published in Scientific reports (08-10-2021)“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia and behavioral changes. Extracellular deposition of amyloid plaques…”
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Pre-transplant depression decreased overall survival of patients receiving allogeneic hematopoietic stem cell transplantation: a nationwide cohort study
Published in Scientific reports (17-09-2020)“…Studies investigating association of depression with overall survival (OS) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) yielded…”
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Sex-Related Disparities in the Resting State Functional Connectivity of the Locus Coeruelus and Salience Network in Preclinical Alzheimer’s Disease
Published in International journal of molecular sciences (01-10-2023)“…Recent studies have demonstrated the pivotal role of locus coeruleus (LC) and salience network (SN) resting state functional connectivity (rsFC) changes in the…”
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