Search Results - "Lim, Hwa J."

Alterations in behavior, amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease by Hwang, Dae Y, Chae, Kab R, Kang, Tae S, Hwang, Jin H, Lim, Chae H, Kang, Hyun K, Goo, Jun S, Lee, Mi R, Lim, Hwa J, Min, Sae H, Cho, Jun Y, Hong, Jin T, Song, Chi W, Paik, Sang G, Cho, Jung S, Kim, Yong K

“…Alzheimer's disease (AD) occurs when neurons in the memory and cognition regions of the brain are accompanied by an accumulation of the long amyloid…”
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Aberrant expressions of pathogenic phenotype in Alzheimer's diseased transgenic mice carrying NSE-controlled APPsw by Hwang, Dae Y., Cho, Jung S., Lee, Su H., Chae, Kab R., Lim, Hwa J., Min, Sea H., Seo, Su J., Song, Youn S., Song, Chi W., Paik, Sang G., Sheen, Yhun Y., Kim, Yong K.

“…Mutations in the APP gene lead to enhanced cleavage by the β- and γ-secretase, and increased Aβ formation, which are tightly associated with Alzheimer's…”
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Tau and GSK3β Dephosphorylations are Required for Regulating Pin1 Phosphorylation by Min, Sae H., Cho, Jung S., Oh, Jae H., Shim, Sun B., Hwang, Dae Y., Lee, Su H., Jee, Seung W., Lim, Hwa J., Kim, Min Y., Sheen, Yhun Y., Lee, Seok H., Kim, Yong K.

“…Pin1 binds mitotically phosphorylated Thr231-Pro232 and Thr212-Pro213 sites on tau, and a Pin1 deficiency in mice leads to tau hyperphosphorylation. The aim of…”
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Use of NSE/PS2m-transgenic mice in the study of the protective effect of exercise on Alzheimer's disease by Cho, Jun Y, Hwang, Dae Y, Kang, Tae S, Shin, Dong H, Hwang, Jin H, Lim, Chae H, Lee, Su H, Lim, Hwa J, Min, Sae H, Seo, Su J, Song, Youn S, Nam, Ki T, Lee, Kyu S, Cho, Jung S, Kim, Yong K

“…In its late stage, Alzheimer's disease results in progressive muscle weakness in the arms and legs. The aim of this study was to determine whether mice…”
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NSE-Controlled Carboxyl-Terminus of APP Gene Over-Expressing in Transgenic Mice Induces Altered Expressions in Behavior, Aβ-42, and GSK3β Binding Proteins by Lim, Hwa J., Cho, Jung S., Oh, Jae H., Shim, Sun B., Hwang, Dae Y., Jee, Seung W., Lee, Su H., Sheen, Yhun Y., Lee, Seok H., Kim, Yong K.

“…The amyloid protein precursor (APP) is cleaved in its intramembranous domain by gamma -secrease to generate amyloid beta and a free carboxyl-terminal…”
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Differential expression of the tetracycline-controlled transactivator-driven human CYP1B1 gene in double-transgenic mice is due to androgens: application for detecting androgens and antiandrogens by Hwang, Dae Y, Cho, Jung S, Chae, Kab R, Kang, Tae S, Hwang, Jin H, Lim, Chae H, Lee, Su H, Lim, Hwa J, Min, Sae H, Sheen, Yhun Y, Jang, In S, Kim, Yong K

“…Differential expression of the tetracycline-controlled transactivator (tTA)-driven human cytochrome P450 (CYP) 1B1 gene was found in the livers of male mice,…”
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Carboxyl-terminus of the amyloid protein precursor and ERbeta are required for estrogenic effect in activating mitogen-activated protein kinase by Lim, Hwa J, Lim, Chul J, Hwang, Dae Y, Lee, Su H, Min, Sae H, Song, Youn S, Seo, Su J, Park, Hye K, Sheen, Yhun Y, Cho, Jung S, Kim, Yong K

“…Estrogen influences the processing of the amyloid beta precursor protein (APP) in the pathogenesis of Alzheimer's disease, and this effect is mediated by…”
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Alterations in behavior, amyloid p‐42, caspase‐3, and Cox‐2 in mutant PS2 transgenic mouse model of Alzheimer's disease by Hwang, Dae Y., Chae, Kab R., Kang, Tae S., Hwang, Jin H., Lim, Chae H., Kang, Hyun K., Goo, Jun S., Lee, Mi R., Lim, Hwa J., Min, Sae H., Cho, Jun Y., Hong, Jin T., Song, Chi W., Paik, Sang G., Cho, Jung S., Kim, Yong K.

“…ABSTRACT Alzheimer's disease (AD) occurs when neurons in the memory and cognition regions of the brain are accompanied by an accumulation of the long amyloid…”
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Differential expression of proteins of caspases and Bcl-2 families in the brain of mice by Min, Se H, Hwang, Dae Y, Kang, Tae S, Hwang, Jin H, Lim, Chae H, Lee, Su H, Lim, Hwa J, Seo, Su J, Sheen, Yhun Y, Paik, Sang G, Cho, Jung S, Kim, Yong K

“…Apoptosis is an important process in the variety of different biological system including cell death and embryonic development. Inappropriate apoptosis is…”
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An in vitro bioassay for xenobiotics using the SXR-Driven human CYP3A4/lacz reporter gene by LEE, Mi R, KIM, Yeon J, CHO, Jung S, CHAE, Kap R, KIM, Yong K, HWANG, Dae Y, KANG, Tae S, HWANG, Jin H, LIM, Chae H, KANG, Hyung K, GOO, Jun S, LIM, Hwa J, AHN, Kwang S

“…The dose and time effect of nine xenobiotics, including 17beta-estradiol, corticosterone, dexamethasone, progesterone, nifedipine, bisphenol A, rifampicin,…”
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An In Vitro Bioassay for Xenobiotics Using the SXR-Driven Human CYP3A4/lac Z Reporter Gene by Lee, Mi R., Kim, Yeon J., Hwang, Dae Y., Kang, Tae S., Hwang, Jin H., Lim, Chae H., Kang, Hyung K., Goo, Jun S., Lim, Hwa J., Ahn, Kwang S., Cho, Jung S., Chae, Kap R., Kim, Yong K.

“…The dose and time effect of nine xenobiotics, including 17β-estradiol, corticosterone, dexamethasone, progesterone, nifedipine, bisphenol A, rifampicin,…”
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P1-091: Aberrant phosphorylation of the human Tau gene in transgenic mice with Alzheimer’s disease by Shim, Sun B., Lim, Hwa J., Cho, Jung S., Kim, Chuel K., Hwang, Dae Y., Jee, Seung W., Lee, Su H., Lee, Se H., Kim, Yong K.

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Tau and GSK3[beta] Dephosphorylations are Required for Regulating Pin1 Phosphorylation by Min, Sae H, Cho, Jung S, Oh, Jae H, Shim, Sun B, Hwang, Dae Y, Lee, Su H, Jee, Seung W, Lim, Hwa J, Kim, Min Y, Sheen, Yhun Y, Lee, Seok H, Kim, Yong K

“…Pin1 binds mitotically phosphorylated Thr231-Pro232 and Thr212-Pro213 sites on tau, and a Pin1 deficiency in mice leads to tau hyperphosphorylation. The aim of…”
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Tau and GSK3beta dephosphorylations are required for regulating Pin1 phosphorylation by Min, Sae H, Cho, Jung S, Oh, Jae H, Shim, Sun B, Hwang, Dae Y, Lee, Su H, Jee, Seung W, Lim, Hwa J, Kim, Min Y, Sheen, Yhun Y, Lee, Seok H, Kim, Yong K

“…Pin1 binds mitotically phosphorylated Thr231-Pro232 and Thr212-Pro213 sites on tau, and a Pin1 deficiency in mice leads to tau hyperphosphorylation. The aim of…”
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NSE-controlled carboxyl-terminus of APP gene over-expressing in transgenic mice induces altered expressions in behavior, Abeta-42, and GSK3beta binding proteins by Lim, Hwa J, Cho, Jung S, Oh, Jae H, Shim, Sun B, Hwang, Dae Y, Jee, Seung W, Lee, Su H, Sheen, Yhun Y, Lee, Seok H, Kim, Yong K

“…The amyloid protein precursor (APP) is cleaved in its intramembranous domain by gamma-secrease to generate amyloid beta and a free carboxyl-terminal…”
Get full text