Search Results - "Lim, Esther B"

Peptide valency plays an important role in the activity of a synthetic fibrin-crosslinking polymer by Lamm, Robert J, Lim, Esther B, Weigandt, Katie M, Pozzo, Lilo D, White, Nathan J, Pun, Suzie H

“…Abstract Therapeutic polymers have the potential to improve the standard of care for hemorrhage, or uncontrolled bleeding, as synthetic hemostats. PolySTAT, a…”
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Post-translational oxidative modification of fibrinogen is associated with coagulopathy after traumatic injury by White, Nathan J., Wang, Yi, Fu, Xiaoyun, Cardenas, Jessica C., Martin, Erika J., Brophy, Donald F., Wade, Charles E., Wang, Xu, St. John, Alexander E., Lim, Esther B., Stern, Susan A., Ward, Kevin R., López, José A., Chung, Dominic

“…Victims of trauma often develop impaired blood clot formation (coagulopathy) that contributes to bleeding and mortality. Fibrin polymerization is one critical…”
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Self-propelled particles that transport cargo through flowing blood and halt hemorrhage by Baylis, James R, Yeon, Ju Hun, Thomson, Max H, Kazerooni, Amir, Wang, Xu, St John, Alex E, Lim, Esther B, Chien, Diana, Lee, Anna, Zhang, Jesse Q, Piret, James M, Machan, Lindsay S, Burke, Thomas F, White, Nathan J, Kastrup, Christian J

“…Delivering therapeutics deep into damaged tissue during bleeding is challenging because of the outward flow of blood. When coagulants cannot reach and clot…”
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Effects of rapid wound sealing on survival and blood loss in a swine model of lethal junctional arterial hemorrhage by St John, Alexander E, Wang, Xu, Lim, Esther B, Chien, Diana, Stern, Susan A, White, Nathan J

“…Hemostatic gauzes, which must be packed into wounds and compressed for several minutes, may be of limited use for noncompressible wounds in junctional anatomic…”
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Increased resistance to tissue plasminogen activator-induced fibrinolysis in healthy subjects from Thailand by White, Nathan J, Taflin, Nicholas, Lim, Esther B, Akaraborworn, Osaree

“…There is significant variability in blood coagulation among world populations. In particular, there may exist important differences in regulation of the…”
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Self-Propelled Dressings Containing Thrombin and Tranexamic Acid Improve Short-Term Survival in a Swine Model of Lethal Junctional Hemorrhage by Baylis, James R, St. John, Alexander E, Wang, Xu, Lim, Esther B, Statz, Matthew L, Chien, Diana, Simonson, Eric, Stern, Susan A, Liggins, Richard T, White, Nathan J, Kastrup, Christian J

“…ABSTRACTHemorrhage is the leading cause of preventable death in trauma, and hemorrhage from noncompressible junctional anatomic sites is particularly difficult…”
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Damage Control Resuscitation Supplemented with Vasopressin in a Severe Polytrauma Model with Traumatic Brain Injury and Uncontrolled Internal Hemorrhage by Dickson, J Michael, Wang, Xu, St John, Alexander E, Lim, Esther B, Stern, Susan A, White, Nathan J

“…Traumatic brain injury (TBI) and hemorrhagic shock (HS) are the leading causes of traumatic death worldwide and particularly on the battlefield. They are…”
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A Multifunctional, Low-Volume Resuscitation Cocktail Improves Vital Organ Blood Flow and Hemostasis in a Pig Model of Polytrauma with Traumatic Brain Injury by St John, Alexander E, Wang, Xu, Ringgold, Kristyn, Lim, Esther B, Chien, Diana, Statz, Matthew L, Stern, Susan A, White, Nathan J

“…The resuscitation of polytrauma with hemorrhagic shock and traumatic brain injury (TBI) is a balance between permissive hypotension and maintaining vital organ…”
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Abstract 12311: Platelet Force Measurements are Predictive of Triage Category and Blood Transfusion After Trauma by White, Nathan J, Ting, Lucas, Lim, Esther B, Karchin, Ari, Wang, Xu, Smith, Annie O, Chien, Diana, Rue, Tessa C, Sniadecki, Nathan

“…IntroductionPlatelets rapidly adhere, aggregate and contract forcefully at wound sites to initiate hemostasis. This process, known as primary hemostasis, is a…”
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