Search Results - "Lim, Carissa J."
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Nr4a1 suppresses cocaine-induced behavior via epigenetic regulation of homeostatic target genes
Published in Nature communications (24-01-2020)“…Endogenous homeostatic mechanisms can restore normal neuronal function following cocaine-induced neuroadaptations. Such mechanisms may be exploited to develop…”
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Neuroepigenetic Editing
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Epigenetic regulation is intrinsic to basic neurobiological function as well as neurological disease. Regulation of chromatin-modifying enzymes in the brain is…”
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Chromatin-mediated alternative splicing regulates cocaine-reward behavior
Published in Neuron (Cambridge, Mass.) (15-09-2021)“…Neuronal alternative splicing is a key gene regulatory mechanism in the brain. However, the spliceosome machinery is insufficient to fully specify splicing…”
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Sex-Specific Regulation of Fear Memory by Targeted Epigenetic Editing of Cdk5
Published in Biological psychiatry (1969) (15-04-2019)“…Sex differences in the expression and prevalence of trauma- and stress-related disorders have led to a growing interest in the sex-specific molecular and…”
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Neuroepigenetic Editing
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…Studies of the mammalian nervous system have revealed widespread epigenetic regulation underlying gene expression intrinsic to basic neurobiological function…”
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Viral Expression of Epigenome Editing Tools in Rodent Brain Using Stereotaxic Surgery Techniques
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…Delivery of molecular tools for targeted epigenome editing in rodent brain can be facilitated by the use of viral vector-mediated gene transfer coupled with…”
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