Search Results - "Lim, Andrew S"

Modification of the relationship of the apolipoprotein E ε4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep by Lim, Andrew S P, Yu, Lei, Kowgier, Matthew, Schneider, Julie A, Buchman, Aron S, Bennett, David A

“…The apolipoprotein E (APOE [GenBank, 348; OMIM, 107741]) ε4 allele is a common and well-established genetic risk factor for Alzheimer disease (AD). Sleep…”
Get more information

Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank by Wainberg, Michael, Jones, Samuel E, Beaupre, Lindsay Melhuish, Hill, Sean L, Felsky, Daniel, Rivas, Manuel A, Lim, Andrew S P, Ollila, Hanna M, Tripathy, Shreejoy J

“…Sleep problems are both symptoms of and modifiable risk factors for many psychiatric disorders. Wrist-worn accelerometers enable objective measurement of sleep…”
Get full text

Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons by Lim, Andrew S P, Kowgier, Matthew, Yu, Lei, Buchman, Aron S, Bennett, David A

“…Cross-sectional studies suggest that sleep fragmentation is associated with cognitive performance in older adults. We tested the hypothesis that sleep…”
Get full text

Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease by LIM, Andrew S. P, ELLISON, Brian A, WANG, Joshua L, LEI YU, SCHNEIDER, Julie A, BUCHMAN, Aron S, BENNETT, David A, SAPER, Clifford B

“…Fragmented sleep is a common and troubling symptom in ageing and Alzheimer's disease; however, its neurobiological basis in many patients is unknown. In…”
Get full text

Correlates of Person-Specific Rates of Change in Sensor-Derived Physical Activity Metrics of Daily Living in the Rush Memory and Aging Project by Buchman, Aron S, Wang, Tianhao, Oveisgharan, Shahram, Zammit, Andrea R, Yu, Lei, Li, Peng, Hu, Kun, Hausdorff, Jeffrey M, Lim, Andrew S P, Bennett, David A

“…This study characterized person-specific rates of change of total daily physical activity (TDPA) and identified correlates of this change. TDPA metrics were…”
Get full text

Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts by Lim, Andrew S P, Gaiteri, Chris, Yu, Lei, Sohail, Shahmir, Swardfager, Walter, Tasaki, Shinya, Schneider, Julie A, Paquet, Claire, Stuss, Donald T, Masellis, Mario, Black, Sandra E, Hugon, Jacques, Buchman, Aron S, Barnes, Lisa L, Bennett, David A, De Jager, Philip L

“…There are few data concerning the association between season and cognition and its neurobiological correlates in older persons-effects with important…”
Get full text

Association Between Quantitative Gait and Balance Measures and Total Daily Physical Activity in Community-Dwelling Older Adults by Dawe, Robert J, Leurgans, Sue E, Yang, Jingyun, Bennett, Joshua M, Hausdorff, Jeffrey M, Lim, Andrew S, Gaiteri, Chris, Bennett, David A, Buchman, Aron S

“…Total daily physical activity is associated with a wide range of adverse health outcomes. We examined the extent to which quantitative measures of gait and…”
Get full text

Retraction: 24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex by Lim, Andrew S. P, Srivastava, Gyan P, Yu, Lei, Chibnik, Lori B, Xu, Jishu, Buchman, Aron S, Schneider, Julie A, Myers, Amanda J, Bennett, David A, De Jager, Philip L

Get full text

Sleep fragmentation and Parkinson's disease pathology in older adults without Parkinson's disease by Sohail, Shahmir, Yu, Lei, Schneider, Julie A., Bennett, David A., Buchman, Aron S., Lim, Andrew S. P.

“…ABSTRACT Introduction Patients with Parkinson's disease (PD) frequently experience disrupted sleep, and several sleep abnormalities are associated with an…”
Get full text

Irregular 24-hour activity rhythms and the metabolic syndrome in older adults by Sohail, Shahmir, Yu, Lei, Bennett, David A, Buchman, Aron S, Lim, Andrew S P

“…Circadian rhythms - near 24 h intrinsic biological rhythms - modulate many aspects of human physiology and hence disruption of circadian rhythms may have an…”
Get more information

Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease by Lim, Andrew S. P., Klein, Hans-Ulrich, Yu, Lei, Chibnik, Lori B., Ali, Sanam, Xu, Jishu, Bennett, David A., De Jager, Philip L.

“…Circadian and seasonal rhythms are seen in many species, modulate several aspects of human physiology, including brain functions such as mood and cognition,…”
Get full text

Circadian disturbances in Alzheimer's disease progression: a prospective observational cohort study of community-based older adults by Li, Peng, Gao, Lei, Gaba, Arlen, Yu, Lei, Cui, Longchang, Fan, Wenqing, Lim, Andrew S P, Bennett, David A, Buchman, Aron S, Hu, Kun

“…Circadian disturbances are commonly seen in people with Alzheimer's disease and have been reported in individuals without symptoms of dementia but with…”
Get full text

A common polymorphism near PER1 and the timing of human behavioral rhythms by Lim, Andrew S. P., Chang, Anne-Marie, Shulman, Joshua M., Raj, Towfique, Chibnik, Lori B., Cain, Sean W., Rothamel, Katherine, Benoist, Christophe, Myers, Amanda J., Czeisler, Charles A., Buchman, Aron S., Bennett, David A., Duffy, Jeanne F., Saper, Clifford B., De Jager, Philip L.

“…Objective: Circadian rhythms influence the timing of behavior, neurological diseases, and even death. Rare mutations in homologs of evolutionarily conserved…”
Get full text

Sleep on the ward in intensive care unit survivors: a case series of polysomnography by Wilcox, Mary Elizabeth, Lim, Andrew S., Pinto, Ruxandra, Black, Sandra E., McAndrews, Mary Pat, Rubenfeld, Gordon D.

“…Background Few studies have investigated sleep in patients after intensive care despite the possibility that inadequate sleep might further complicate an acute…”
Get full text

Selective enhancement of rapid eye movement sleep by deep brain stimulation of the human pons by Lim, Andrew S., Moro, Elena, Lozano, Andres M., Hamani, Clement, Dostrovsky, Jonathan O., Hutchison, William D., Lang, Anthony E., Wennberg, Richard A., Murray, Brian J.

“…Animal studies suggest that rapid eye movement (REM) sleep is governed by the interaction of REM‐promoting and REM‐inhibiting nuclei in the pontomesencephalic…”
Get full text

24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex by Lim, Andrew S P, Srivastava, Gyan P, Yu, Lei, Chibnik, Lori B, Xu, Jishu, Buchman, Aron S, Schneider, Julie A, Myers, Amanda J, Bennett, David A, De Jager, Philip L

“…Circadian rhythms modulate the biology of many human tissues, including brain tissues, and are driven by a near 24-hour transcriptional feedback loop. These…”
Get full text

Locus coeruleus neuron density and parkinsonism in older adults without Parkinson's disease by Buchman, Aron S., Nag, Sukriti, Shulman, Joshua M., Lim, Andrew S.P., VanderHorst, Veronique G.J.M., Leurgans, Sue E., Schneider, Julie A., Bennett, David A.

“…Previous work has showed that nigral neuron density is related to the severity of parkinsonism proximate to death in older persons without a clinical diagnosis…”
Get full text

Characterization of REM-sleep associated ponto-geniculo-occipital waves in the human pons by LIM, Andrew S, LOZANO, Andres M, MORO, Elena, HAMANI, Clement, HUTCHISON, William D, DOSTROVSKY, Jonathan O, LANG, Anthony E, WENNBERG, Richard A, MURRAY, Brian J

“…Ponto-geniculo-occipital (PGO) waves are phasic pontine, lateral geniculate, and cortical field potentials occurring during and before REM sleep that are…”
Get full text

Small Polar Hits against S. aureus: Screening, Initial Hit Optimization, and Metabolomic Studies by Lim, Andrew S. T, Vincent, Isabel M, Barrett, Michael P, Gilbert, Ian H

“…The global prevalence of antibacterial resistance requires new antibacterial drugs with novel chemical scaffolds and modes of action. It is also vital to…”
Get full text

Sex Difference in Daily Rhythms of Clock Gene Expression in the Aged Human Cerebral Cortex by Lim, Andrew S.P., Myers, Amanda J., Yu, Lei, Buchman, Aron S., Duffy, Jeanne F., De Jager, Philip L., Bennett, David A.

“…Studies using self-report and physiological markers of circadian rhythmicity have demonstrated sex differences in a number of circadian attributes including…”
Get full text