Search Results - "Lilyanna, Shera"
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Epitope-directed monoclonal antibody production using a mixed antigen cocktail facilitates antibody characterization and validation
Published in Communications biology (06-04-2021)“…High quality, well-validated antibodies are needed to mitigate irreproducibility and clarify conflicting data in science. We describe an epitope-directed…”
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MicroRNA-31 promotes adverse cardiac remodeling and dysfunction in ischemic heart disease
Published in Journal of molecular and cellular cardiology (01-11-2017)“…Myocardial infarction (MI) triggers a dynamic microRNA response with the potential of yielding therapeutic targets. We aimed to identify novel aberrantly…”
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Multiple circulating forms of neprilysin detected with novel epitope-directed monoclonal antibodies
Published in Cellular and molecular life sciences : CMLS (01-12-2024)“…Neprilysin (NEP) is an emerging biomarker for various diseases including heart failure (HF). However, major inter-assay inconsistency in the reported…”
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GYY4137 attenuates remodeling, preserves cardiac function and modulates the natriuretic peptide response to ischemia
Published in Journal of molecular and cellular cardiology (01-10-2015)“…Abstract Aims Myocardial infarction followed by adverse left ventricular (LV) remodeling is the most frequent proximate cause of heart failure. Hydrogen…”
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Finding a reliable assay for soluble neprilysin
Published in Clinical biochemistry (01-06-2022)“…[Display omitted] Lack of validation and standardization of research-use-only (RUO) immunoassays brings with it inherent threats to authenticity and functional…”
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Abstract 15090: Circulating miR-503 and miR-374b-5p are associated With Heart Failure
Published in Circulation (New York, N.Y.) (10-11-2015)“…IntroductionCirculating microRNA (miRNAs) profiles are dysregulated in heart failure (HF) suggesting possible diagnostic and prognostic applications. In…”
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Abstract 107: MicroRNA-31: A Novel Therapeutic Target for Ischemic Heart Disease
Published in Circulation research (18-07-2014)“…Abstract only MicroRNAs (miRNA), small sequences of non-coding RNA which interact with complementary sequences on the 3’untranslated region of target messenger…”
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Immunoassay-Compatible Inactivation of SARS-CoV‑2 in Plasma Samples for Enhanced Handling Safety
Published in ACS omega (26-07-2022)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) inactivation is an important step toward enhanced biosafety in testing facilities and affords a…”
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Abstract 106: GYY4137 Attenuates Post-Ischemic Adverse Remodeling and Modulates ANP-Mediated cGMP Signal Transduction
Published in Circulation research (18-07-2014)“…Abstract only Myocardial infarction is the most frequent proximate cause of heart failure, which remains a leading cause of death in the developed world…”
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Natriuretic peptide receptor 3 (NPR3) is regulated by microRNA-100
Published in Journal of molecular and cellular cardiology (01-05-2015)“…Abstract Natriuretic peptide receptor 3 (NPR3) is the clearance receptor for the cardiac natriuretic peptides (NPs). By modulating the level of NPs, NPR3 plays…”
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Cord lining-mesenchymal stem cells graft supplemented with an omental flap induces myocardial revascularization and ameliorates cardiac dysfunction in a rat model of chronic ischemic heart failure
Published in Tissue engineering. Part A (01-06-2013)“…Myocardial restoration using tissue-engineered grafts to regenerate the ischemic myocardium offers improved donor cell retention, yet a limited cell survival…”
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Grafts enriched with subamnion-cord-lining mesenchymal stem cell angiogenic spheroids induce post-ischemic myocardial revascularization and preserve cardiac function in failing rat hearts
Published in Stem cells and development (01-12-2013)“…A crucial question in post-ischemic cell therapy refers to the ideal method of cell delivery to the heart. We hypothesized that epicardial implantation of…”
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Variability in Microplate Surface Properties and Its Impact on ELISA
Published in The journal of applied laboratory medicine (01-03-2018)“…Microplate-based immunoassays are widely used in clinical and research settings to measure a broad range of biomarkers present in complex matrices. Assay…”
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Post-ischaemic angiogenic therapy using in vivo prevascularized ascorbic acid-enriched myocardial artificial grafts improves heart function in a rat model: Vascularized grafts for myocardial repair
Published in Journal of tissue engineering and regenerative medicine (01-03-2013)Get full text
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Post-ischaemic angiogenic therapy using in vivo prevascularized ascorbic acid-enriched myocardial artificial grafts improves heart function in a rat model
Published in Journal of tissue engineering and regenerative medicine (01-03-2013)“…Angiogenesis plays a key role in post‐ischaemic myocardial repair. We hypothesized that epicardial implantation of an ascorbic acid (AA)‐enriched myocardial…”
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