Search Results - "Lillard, James"

Reversal of drug resistance by planetary ball milled (PBM) nanoparticle loaded with resveratrol and docetaxel in prostate cancer by Singh, Santosh Kumar, Lillard, James W., Singh, Rajesh

“…The folate receptor (FR) is a valued target that is highly expressed in various cancers, which will expedite the development of ligand-receptor binding based…”
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Racial disparities in Black men with prostate cancer: A literature review by Lillard, James W., Moses, Kelvin A., Mahal, Brandon A., George, Daniel J.

“…Black men are disproportionately affected by prostate cancer (PCa), with earlier presentation, more aggressive disease, and higher mortality rates versus White…”
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Nanoparticle-based targeted drug delivery by Singh, Rajesh, Lillard, James W.

“…Nanotechnology could be defined as the technology that has allowed for the control, manipulation, study, and manufacture of structures and devices in the…”
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Drug delivery approaches for breast cancer by Singh, Santosh Kumar, Singh, Shriti, Lillard, Jr, James W, Singh, Rajesh

“…Breast cancer is one of the most common cancers affecting women worldwide. The controlled release of drugs to the precise site of the disease using a…”
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CCR5/CCL5 axis interaction promotes migratory and invasiveness of pancreatic cancer cells by Singh, Santosh Kumar, Mishra, Manoj K., Eltoum, Isam-Eldin A., Bae, Sejong, Lillard, James W., Singh, Rajesh

“…Pancreatic cancer (PC) is one of the deadliest cancers and remains a major challenge due to its invasive and metastatic nature. Increased levels of CCR5 and…”
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Resveratrol induces cell cycle arrest and apoptosis with docetaxel in prostate cancer cells via a p53/ p21WAF1/CIP1 and p27KIP1 pathway by Singh, Santosh Kumar, Banerjee, Saswati, Acosta, Edward P, Lillard, James W, Singh, Rajesh

“…Resveratrol (RES) is the most effective natural products used for the treatment of a variety of cancers. In this study, we tested the effect of RES in…”
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Bridges to biotechnology and bioentrepreneurship: improving diversity in the biotechnology sector by Howard, Angelita P., Slaughter, Liane S., Carey, Kaylin M., Lillard, James W.

“…A summer pipeline program provides under-represented students from around the United States with exposure and first-hand training to advance their careers in…”
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Expression and clinical significance of CXCR5/CXCL13 in human non-small cell lung carcinoma by SINGH, RAJESH, GUPTA, PRANAV, KLOECKER, GOETZ H, SINGH, SHAILESH, LILLARD, JAMES W

“…CXCR5 and/or CXCL13 expression is elevated in certain carcinomas and lymphomas. To determine if these factors are involved in progression of non-small cell…”
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Role of natural compounds in preventing and treating breast cancer by Noel, Brianna, Singh, Santosh Kumar, Lillard, Jr, James W, Singh, Rajesh

“…Breast cancer (BrCa) is the most commonly diagnosed cancer and the second leading cause of cancer-related death in women. Alarming increases in the cases…”
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Andrographolide inhibits prostate cancer by targeting cell cycle regulators, CXCR3 and CXCR7 chemokine receptors by Mir, Hina, Kapur, Neeraj, Singh, Rajesh, Sonpavde, Guru, Lillard, Jr, James W, Singh, Shailesh

“…Despite state of the art cancer diagnostics and therapies offered in clinic, prostate cancer (PCa) remains the second leading cause of cancer-related deaths…”
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Combinatorial effect of curcumin with docetaxel modulates apoptotic and cell survival molecules in prostate cancer by Banerjee, Saswati, Singh, Santosh K, Chowdhury, Indrajit, Lillard, Jr, James W, Singh, Rajesh

“…Docetaxel is the most commonly used chemotherapeutic agent to target androgen signaling in metastatic prostate cancer (PCa); however, prolonged treatment with…”
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Prostate cancer cells hyper-activate CXCR6 signaling by cleaving CXCL16 to overcome effect of docetaxel by Kapur, Neeraj, Mir, Hina, Sonpavde, Guru P., Jain, Sanjay, Bae, Sejong, Lillard, James W., Singh, Shailesh

“…Molecular reprogramming in response to chemotherapeutics leads to poor therapeutic outcomes for prostate cancer (PCa). In this study, we demonstrated that…”
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Past, present, and future technologies for oral delivery of therapeutic proteins by Singh, Rajesh, Singh, Shailesh, Lillard, Jr, James W

“…Biological drugs are usually complex proteins and cannot be orally delivered due to problems related to degradation in the acidic and protease-rich environment…”
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CXCR6-CXCL16 axis promotes prostate cancer by mediating cytoskeleton rearrangement via Ezrin activation and αvβ3 integrin clustering by Singh, Rajesh, Kapur, Neeraj, Mir, Hina, Singh, Nalinaksha, Lillard, Jr, James W, Singh, Shailesh

“…Cytoskeletal rearrangement is required for migration and invasion, which are the key steps of cancer metastasis. Ezrin and integrin co-ordinate these processes…”
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A Comprehensive Review of Bioinformatics Tools for Genomic Biomarker Discovery Driving Precision Oncology by Clark, Alexis J, Lillard, Jr, James W

“…The rapid advancement of high-throughput technologies, particularly next-generation sequencing (NGS), has revolutionized cancer research by enabling the…”
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Higher CXCL16 exodomain is associated with aggressive ovarian cancer and promotes the disease by CXCR6 activation and MMP modulation by Mir, Hina, Kaur, Gurpreet, Kapur, Neeraj, Bae, Sejong, Lillard, James W., Singh, Shailesh

“…Ovarian cancer (OvCa) is the leading cause of death from gynecological malignancies. Five-year survival rate of OvCa ranges from 30–92%, depending on the…”
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Molecular basis for prostate cancer racial disparities by Singh, Santosh K, Lillard, Jr, James W, Singh, Rajesh

“…Prostate cancer (PCa) remains the most common cancer in American men. African-American (AA) men continue to have higher PCa prevalence and mortality rates…”
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PI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cells by El Haibi, Christelle P, Sharma, Praveen K, Singh, Rajesh, Johnson, Paul R, Suttles, Jill, Singh, Shailesh, Lillard, Jr, James W

“…Most prostate cancer (PCa)-related deaths are due to metastasis, which is mediated in part by chemokine receptor and corresponding ligand interaction. We have…”
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Transcriptome Network Analysis Identifies CXCL13-CXCR5 Signaling Modules in the Prostate Tumor Immune Microenvironment by Ohandjo, Adaugo Q., Liu, Zongzhi, Dammer, Eric B., Dill, Courtney D., Griffen, Tiara L., Carey, Kaylin M., Hinton, Denise E., Meller, Robert, Lillard, James W.

“…The tumor immune microenvironment (TIME) consists of multiple cell types that contribute to the heterogeneity and complexity of prostate cancer (PCa). In this…”
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Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells by Dixit, Vishwa Deep, Schaffer, Eric M, Pyle, Robert S, Collins, Gary D, Sakthivel, Senthil K, Palaniappan, Ravichandran, Lillard, Jr, James W, Taub, Dennis D

“…Ghrelin, a recently described endogenous ligand for the growth hormone secretagogue receptor (GHS-R), is produced by stomach cells and is a potent circulating…”
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