Search Results - "Lilja, Hans G."

Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases by Kallio, Heini M. L., Hieta, Reija, Latonen, Leena, Brofeldt, Anniina, Annala, Matti, Kivinummi, Kati, Tammela, Teuvo L., Nykter, Matti, Isaacs, William B., Lilja, Hans G., Bova, G. Steven, Visakorpi, Tapio

“…Background A significant subset of prostate cancer (PC) patients with a castration-resistant form of the disease (CRPC) show primary resistance to androgen…”
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The Added Value of Percentage of Free to Total Prostate-specific Antigen, PCA3, and a Kallikrein Panel to the ERSPC Risk Calculator for Prostate Cancer in Prescreened Men by Vedder, Moniek M, de Bekker-Grob, Esther W, Lilja, Hans G, Vickers, Andrew J, van Leenders, Geert J.L.H, Steyerberg, Ewout W, Roobol, Monique J

“…Abstract Background Prostate-specific antigen (PSA) testing has limited accuracy for the early detection of prostate cancer (PCa). Objective To assess the…”
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Validation of prostate cancer risk variants rs10993994 and rs7098889 by CRISPR/Cas9 mediated genome editing by Wang, Xing, Hayes, James E., Xu, Xing, Gao, Xiaoni, Mehta, Dipti, Lilja, Hans G., Klein, Robert J.

“…•Editing of heterozygous regulatory elements reveals allele-specific effects.•Gene editing shows which gene is the target of a prostate cancer risk SNP.•Double…”
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The Four-Kallikrein Panel Is Effective in Identifying Aggressive Prostate Cancer in a Multiethnic Population by Darst, Burcu F, Chou, Alisha, Wan, Peggy, Pooler, Loreall, Sheng, Xin, Vertosick, Emily A, Conti, David V, Wilkens, Lynne R, Le Marchand, Loïc, Vickers, Andrew J, Lilja, Hans G, Haiman, Christopher A

“…The four-kallikrein (4K) panel has been demonstrated to improve prediction of aggressive prostate cancer compared with prostate-specific antigen (PSA) among…”
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NF-κB Regulates Androgen Receptor Expression and Prostate Cancer Growth by Zhang, Liying, Altuwaijri, Saleh, Deng, Fangming, Chen, Lishi, Lal, Priti, Bhanot, Umeshkumar K, Korets, Ruslan, Wenske, Sven, Lilja, Hans G, Chang, Chawnshang, Scher, Howard I, Gerald, William L

“…Prostate cancers that progress during androgen-deprivation therapy often overexpress the androgen receptor (AR) and depend on AR signaling for growth. In most…”
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Harnessing Androgen Receptor Pathway Activation for Targeted Alpha Particle Radioimmunotherapy of Breast Cancer by Thorek, Daniel L J, Ku, Anson T, Mitsiades, Nicholas, Veach, Darren, Watson, Philip A, Metha, Dipti, Strand, Sven-Erik, Sharma, Sai Kiran, Lewis, Jason S, Abou, Diane S, Lilja, Hans G, Larson, Steven M, McDevitt, Michael R, Ulmert, David

“…The impact of androgen receptor (AR) activity in breast cancer biology is unclear. We characterized and tested a novel therapy to an AR-governed target in…”
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MP39-11 BASELINE PSA BEFORE AGE 60 AS A PREDICTOR OF IMPORTANT PROSTATE CANCER DIAGNOSIS AND PROSTATE CANCER-SPECIFIC MORTALITY IN THE INTERVENTION ARM OF THE PROSTATE, LUNG, COLORECTAL AND OVARIAN TRIAL by Kovac, Evan, Carlsson, Sigrid, Lilja, Hans G, Hugosson, Jonas, Kattan, Michael, Holmberg, Erik, Stephenson, Andrew J

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Suitability of quality control materials for prostate-specific antigen (PSA) measurement: inter-method variability of common tumor marker control materials by Vucetic, Zivjena, Dnistrian, Ann, Nilsson, Olle, Lilja, Hans G, Plebani, Mario

“…Quality control materials with minimal inter-assay differences and clinically relevant proportions of different molecular forms of the analyte are needed to…”
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Aminopeptidase activities as prospective urinary biomarkers for bladder cancer by Taylor, Jennifer M., Yaneva, Mariana, Velasco, Kevin, Philip, John, Erdjument-Bromage, Hediye, Ostrovnaya, Irina, Lilja, Hans G., Bochner, Bernard H., Tempst, Paul

“…Purpose Proteases have been implicated in cancer progression and invasiveness. We have investigated the activities, as opposed to simple protein levels, of…”
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Abstract PR-16: Serum prostate-specific antigen levels and prostate cancer risk in a multiethnic population by Chou, Alisha, Darst, Burcu F., Wilkens, Lynne R., Marchand, Loïc Le, Lilja, Hans G., Conti, David V., Haiman, Christopher A.

“…Abstract Purpose: While prostate-specific antigen (PSA) is the most commonly used biomarker for prostate cancer (PCa) screening, multiple studies in the U.S…”
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Abstract 1802: Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases by Kallio, Heini M., Hieta, Reija, Brofeldt, Anniina, Annala, Matti, Kivinummi, Kati, Tammela, Teuvo L., Nykter, Matti, Isaacs, William B., Lilja, Hans G., Bova, G Steven, Visakorpi, Tapio

“…Abstract Prostate cancer (PC) is the most commonly diagnosed male cancer both in the United States and in Europe. Approximately 20-25% of cases will develop…”
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Abstract 2566: Comprehensive analysis to identify functional basis of prostate cancer risk SNPs by Middha, Mridu, Xu, Xing, Vaananen, Riina-Minna, Hayes, James, Taimen, Pekka, Gao, Xiaoni, Lilja, Hans G., Pettersson, Kim, Klein, Robert J.

“…Abstract Introduction: Genome-wide association studies (GWAS) have identified numerous common single nucleotide polymorphisms (SNPs) associated with the risk…”
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Emerging PSA-Based Tests to Improve Screening by Bryant, Richard J., FRCSEd(Urol), PhD, Lilja, Hans, MD, PhD

“…This article updates advances in prostate cancer screening based on prostate-specific antigen, its derivatives, and human kallikrein markers. Many men are…”
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NF-kappaB regulates androgen receptor expression and prostate cancer growth by Zhang, Liying, Altuwaijri, Saleh, Deng, Fangming, Chen, Lishi, Lal, Priti, Bhanot, Umeshkumar K, Korets, Ruslan, Wenske, Sven, Lilja, Hans G, Chang, Chawnshang, Scher, Howard I, Gerald, William L

“…Prostate cancers that progress during androgen-deprivation therapy often overexpress the androgen receptor (AR) and depend on AR signaling for growth. In most…”
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NF-{kappa}B Regulates Androgen Receptor Expression and Prostate Cancer Growth by Zhang, Liying, Altuwaijri, Saleh, Deng, Fangming, Chen, Lishi, Lal, Priti, Bhanot, Umeshkumar K, Korets, Ruslan, Wenske, Sven, Lilja, Hans G, Chang, Chawnshang, Scher, Howard I, Gerald, William L

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