Search Results - "Liku, Muluye E."

The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma by von Figura, Guido, Fukuda, Akihisa, Roy, Nilotpal, Liku, Muluye E., Morris IV, John P., Kim, Grace E., Russ, Holger A., Firpo, Matthew A., Mulvihill, Sean J., Dawson, David W., Ferrer, Jorge, Mueller, William F., Busch, Anke, Hertel, Klemens J., Hebrok, Matthias

“…Pancreatic ductal adenocarcinoma (PDA) develops through distinct precursor lesions, including pancreatic intraepithelial neoplasia (PanIN) and intraductal…”
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NoLogo: a new statistical model highlights the diversity and suggests new classes of Crm1-dependent nuclear export signals by Liku, Muluye E, Legere, Elizabeth-Ann, Moses, Alan M

“…Crm1-dependent Nuclear Export Signals (NESs) are clusters of alternating hydrophobic and non-hydrophobic amino acid residues between 10 to 15 amino acids in…”
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Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites by Moses, Alan M, Liku, Muluye E, Li, Joachim J, Durbin, Richard

“…Evolutionary change in gene regulation is a key mechanism underlying the genetic component of organismal diversity. Here, we study evolution of regulation at…”
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CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication by Liku, Muluye E, Nguyen, Van Q, Rosales, Audrey W, Irie, Kaoru, Li, Joachim J

“…Cyclin-dependent kinases (CDKs) use multiple mechanisms to block reassembly of prereplicative complexes (pre-RCs) at replication origins to prevent…”
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Directed differentiation of human pluripotent stem cells along the pancreatic endocrine lineage by Van Hoof, Dennis, Liku, Muluye E

“…Many research groups are engaged in using human pluripotent stem cells (hPSCs) to generate surrogate pancreatic β-cells for transplantation into diabetic…”
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CDK Phosphorylation of a Novel NLS-NES Module Distributed between Two Subunits of the Mcm2-7 Complex Prevents Chromosomal RereplicationD by Liku, Muluye E., Nguyen, Van Q., Rosales, Audrey W., Irie, Kaoru, Li, Joachim J.

“…Cyclin-dependent kinases (CDKs) use multiple mechanisms to block reassembly of prereplicative complexes (pre-RCs) at replication origins to prevent…”
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CDK regulation of replication proteins: Mcm2-7 and DNA polymerase alpha primase by Liku, Muluye E

“…The precise inheritance of genetic material requires that eukaryotic cells initiate DNA replication in a highly regulated manner. To prevent any inappropriate…”
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