Search Results - "Likhatskaya, Galina"
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1
Genome-Wide Analysis of PL7 Alginate Lyases in the Genus Zobellia
Published in Molecules (Basel, Switzerland) (20-04-2021)“…We carried out a detailed investigation of PL7 alginate lyases across the genus. The main findings were obtained using the methods of comparative genomics and…”
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2
Effect of Phlorotannins from Brown Algae Costaria costata on α- N -Acetylgalactosaminidase Produced by Duodenal Adenocarcinoma and Melanoma Cells
Published in Marine drugs (30-12-2022)“…The inhibitor of human α-N-acetylgalactosaminidase (α-NaGalase) was isolated from a water-ethanol extract of the brown algae . Currently, tumor α-NaGalase is…”
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3
Molecular Cloning and Characteristics of a Lectin from the Bivalve Glycymeris yessoensis
Published in Marine drugs (17-01-2023)“…C-type lectins (CTLs) are a family of carbohydrate-binding proteins that mediate multiple biological events, including adhesion between cells, the turnover of…”
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4
Recombinant Production and Characterization of a Highly Active Alkaline Phosphatase from Marine Bacterium Cobetia marina
Published in Marine biotechnology (New York, N.Y.) (01-04-2015)“…The psychrophilic marine bacterium, Cobetia marina , recovered from the mantle tissue of the marine mussel, Crenomytilus grayanus , which contained a gene…”
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5
Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells
Published in IUBMB life (01-12-2024)“…Lectins are carbohydrate‐binding proteins, whose biological effects are exerted via binding to glycoconjugates expressed on the surface of cells. Exposure to…”
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6
Neuroprotective Effect of 1,4-Naphthoquinones in an In Vitro Model of Paraquat and 6-OHDA-Induced Neurotoxicity
Published in International journal of molecular sciences (14-09-2021)“…Targeted screening using the MTT cell viability test with a mini-library of natural and synthetic 1,4-naphthoquinones and their derivatives was performed in…”
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7
The Anti-Inflammatory Effect of Carrageenan/Echinochrom Complex at Experimental Endotoxemia
Published in International journal of molecular sciences (01-10-2022)“…The anti-inflammatory effects of the CRG/Ech complex in LPS-induced endotoxemia were investigated in vivo in mice and in vitro in LPS-stimulated RAW 264.7…”
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8
Protection Activity of 1,4-Naphthoquinones in Rotenone-Induced Models of Neurotoxicity
Published in Marine drugs (01-01-2024)“…The MTS cell viability test was used to screen a mini library of natural and synthetic 1,4-naphthoquinone derivatives (1,4-NQs) from marine sources. This…”
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9
Anti-Inflammatory Activity of 1,4-Naphthoquinones Blocking P2X7 Purinergic Receptors in RAW 264.7 Macrophage Cells
Published in Toxins (05-01-2023)“…P2X7 receptors are ligand-gated ion channels activated by ATP and play a significant role in cellular immunity. These receptors are considered as a potential…”
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10
A Novel Alkaline Phosphatase/Phosphodiesterase, CamPhoD, from Marine Bacterium Cobetia amphilecti KMM 296
Published in Marine drugs (22-11-2019)“…A novel extracellular alkaline phosphatase/phosphodiesterase from the structural protein family PhoD that encoded by the genome sequence of the marine…”
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11
Antiviral Potential of Sea Urchin Aminated Spinochromes against Herpes Simplex Virus Type 1
Published in Marine drugs (05-11-2020)“…Herpes simplex virus type 1 (HSV-1) is one of the most prevalent pathogens worldwide requiring the search for new candidates for the creation of antiherpetic…”
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12
Influence of the Structural Features of Carrageenans from Red Algae of the Far Eastern Seas on Their Antiviral Properties
Published in Marine drugs (01-01-2022)“…The structural diversity and unique physicochemical properties of sulphated polysaccharides of red algae carrageenans (CRGs), to a great extent, determine the…”
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13
In Vitro Anti-Orthohantavirus Activity of the High-and Low-Molecular-Weight Fractions of Fucoidan from the Brown Alga Fucus evanescens
Published in Marine drugs (15-10-2021)“…The Hantaan orthohantavirus (genovariant Amur-AMRV) is a rodent-borne zoonotic virus; it is the causative agent of haemorrhagic fever with renal syndrome in…”
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14
Mutagenesis Studies and Structure-function Relationships for GalNAc/Gal-Specific Lectin from the Sea Mussel Crenomytilus grayanus
Published in Marine drugs (27-11-2018)“…The GalNAc/Gal-specific lectin from the sea mussel (CGL) with anticancer activity represents а novel lectin family with β-trefoil fold. Earlier, the crystal…”
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15
Sponge-derived polybrominated diphenyl ethers and dibenzo-p-dioxins, irreversible inhibitors of the bacterial α-d-galactosidase
Published in Environmental science--processes & impacts (16-10-2019)“…An integrated in vitro and in silico approach was applied to evaluate the potency of hydroxylated polybrominated diphenyl ethers (OH-PBDEs) and spongiadioxins…”
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16
Tetracyclic 1,4-Naphthoquinone Thioglucoside Conjugate U-556 Blocks the Purinergic P2X7 Receptor in Macrophages and Exhibits Anti-Inflammatory Activity In Vivo
Published in International journal of molecular sciences (01-08-2023)“…P2X7 receptors (P2X7Rs) are ligand-gated ion channels that play a significant role in inflammation and are considered a potential therapeutic target for some…”
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17
In Vitro and In Silico Studies of Human Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) Inhibition by Stereoisomeric Forms of Lipophilic Nucleosides: The Role of Carbohydrate Stereochemistry in Ligand-Enzyme Interactions
Published in Molecules (Basel, Switzerland) (09-04-2022)“…Inhibition of human DNA repair enzyme tyrosyl-DNA phosphodiesterase 1 (Tdp1) by different chiral lipophilic nucleoside derivatives was studied. New Tdp1…”
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18
Relationship between the structure of a highly regular fucoidan from Fucus evanescens and its ability to form nanoparticles
Published in International journal of biological macromolecules (31-08-2021)“…Chitosan/fucoidan nanoparticles were created using two fucoidans from the Fucus evanescens algae. One of them was a regular fucoidan obtained for the first…”
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19
Synthesis, Cytotoxic Activity Evaluation and Quantitative Structure-ActivityAnalysis of Substituted 5,8-Dihydroxy-1,4-naphthoquinones and Their O- and S-Glycoside Derivatives Tested against Neuro-2a Cancer Cells
Published in Marine drugs (01-12-2020)“…Based on 6,7-substituted 2,5,8-trihydroxy-1,4-naphtoquinones (1,4-NQs) derived from sea urchins, five new acetyl-O-glucosides of NQs were prepared. A new…”
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20
Porin from Marine Bacterium Marinomonas primoryensis KMM 3633T: Isolation, Physico-Chemical Properties, and Functional Activity
Published in Molecules (Basel, Switzerland) (08-07-2020)“…Marinomonas primoryensis KMM 3633T, extreme living marine bacterium was isolated from a sample of coastal sea ice in the Amursky Bay near Vladivostok, Russia…”
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