Search Results - "Liguri, G"
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Seladin‐1/DHCR24 protects neuroblastoma cells against Aβ toxicity by increasing membrane cholesterol content
Published in Journal of cellular and molecular medicine (01-10-2008)“…The role of brain cholesterol in Alzheimer's disease (AD) is currently a matter of debate. Experimental evidence suggests that reducing circulating and brain…”
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Acylphosphatase overexpression triggers SH-SY5Y differentiation towards neuronal phenotype
Published in Cellular and molecular life sciences : CMLS (01-07-2004)“…An acylphosphatase (AcPase) overexpression study was carried out on SH-SY5Y neuroblastoma cells, using a green fluorescent fusion protein (AcP-GFP), with GFP…”
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Modification of plasma glycosaminoglycans in long distance runners
Published in British journal of sports medicine (01-04-2004)“…Background: It is well documented that exercise reduces the risk of thromboembolic disease, possibly by increasing the plasma concentration of…”
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Possible role of acylphosphatase, Bcl-2 and Fas/Fas-L system in the early changes of cardiac remodeling induced by volume overload
Published in Biochimica et biophysica acta (30-07-2003)“…To identify early adaptive processes of cardiac remodeling (CR) in response to volume overload, we investigated the molecular events that may link…”
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Cholesterol in Alzheimer's disease: unresolved questions
Published in Current Alzheimer research (01-02-2009)“…The role of cholesterol as a susceptibility factor or a protective agent in neurodegeneration and, more generally, in amyloid-induced cytotoxicity is still…”
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Interaction between acylphosphatase and SERCA in SH-SY5Y cells
Published in Molecular and cellular biochemistry (01-08-2000)“…Ca2+ transport by sarco/endoplasmic reticulum, tightly coupled with the enzymatic activity of Ca2+ -dependent ATPase, controls the cell cycle through the…”
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Alteration of Free Calcium Levels and Acylphosphatase Muscular Isoenzyme in Cultured Dystrophic Skin Fibroblasts
Published in Biochemical and biophysical research communications (13-01-1997)“…Levels of free intracellular calcium have been measured on two cell lines of cultured human fibroblasts carrying the genetic lesions occurring in Duchenne and…”
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Post-mortem modifications of the specific activity of some brain enzymes
Published in Neuroscience letters (29-02-1988)“…The post-mortem stability of some brain enzymes was studied. Over the time period under examination, the cytoplasmic enzymes investigated underwent a decisive…”
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Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates
Published in Journal of cell science (01-08-2005)“…It has been reported that different tissue or cultured cell types are variously affected by the exposure to toxic protein aggregates, however a substantial…”
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Oxidative stress and reduced antioxidant defenses in peripheral cells from familial Alzheimer’s patients
Published in Free radical biology & medicine (15-11-2002)“…We have measured the levels of typical end products of the processes of lipid peroxidation, protein oxidation, and total antioxidant capacity (TAC) in skin…”
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Cerebral soluble ubiquitin is increased in patients with Alzheimer's disease
Published in Neuroscience letters (19-03-1993)“…A study concerning the amount of soluble ubiquitin in different cortical and subcortical regions of brains from patients with Alzheimer's disease compared to…”
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Effects of acylphosphatase on the activity of erythrocyte membrane Ca2+ pump
Published in The Journal of biological chemistry (15-06-1991)“…Acylphosphatase, purified from human erythrocytes, actively hydrolyzes the acylphosphorylated intermediate of human red blood cell membrane Ca(2+)-ATPase. This…”
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Immunoaffinity purification and immunoassay determination of human erythrocyte acylphosphatase
Published in Biotechnology and applied biochemistry (01-08-1990)“…Specific anti-human erythrocyte acylphosphatase antibodies were raised in rabbits, purified by affinity chromatography, and used to develop an enzyme…”
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Increased acylphosphatase levels in erythrocytes, muscle and liver of tri-iodothyronine treated rabbits
Published in Hormone and metabolic research (01-01-1990)“…To explore a possible role of acylphosphatase in the regulation of energy metabolism, we measured this enzyme's activity and content in skeletal muscle, liver…”
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Effect of acylphosphatase on human erythrocyte membrane Ca2(+)-ATPase
Published in Biochemical and biophysical research communications (30-04-1990)“…We studied the effect of human acylphosphatase on the activity of human erythrocyte membrane Ca2(+)-ATPase. Both the acylphosphatase that is contained in…”
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Acylphosphatase increases the rate of ethanol production from glucose in cell-free extracts of Saccharomyces cerevisiae
Published in Biotechnology and applied biochemistry (01-10-1988)“…Addition of acylphosphatase exerted a stimulating effect on the alcoholic fermentation of glucose by Saccharomyces cerevisiae. The rates of glucose degradation…”
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Changes in Na+,K(+)-ATPase, Ca2(+)-ATPase and some soluble enzymes related to energy metabolism in brains of patients with Alzheimer's disease
Published in Neuroscience letters (04-05-1990)“…Hexokinase, lactate dehydrogenase, acylphosphatase, (Na+,K+)-ATPase and Ca2(+)-ATPase of selected areas from postmortem Alzheimer's disease brains were…”
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Gluthatione level is altered in lymphoblasts from patients with familial Alzheimer's disease
Published in Neuroscience letters (12-11-1999)“…Intracellular levels of glutathione (GSH), glutathione disulphide (GSSG), glutamic acid and gamma-glutamyl cysteine synthetase (gamma-GCS) were measured in…”
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Affinity chromatographic purification of horse muscle acylphosphatase: evidence of the existence of multiple molecular forms
Published in Archives of biochemistry and biophysics (15-10-1983)“…Acylphosphatase was purified from horse muscle by a new procedure involving an affinity chromatography step and subsequent ion-exchange chromatography. This…”
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