Search Results - "Ligtenberg, M A"
-
1
Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma
Published in Journal of translational medicine (03-07-2020)“…The tumor immune microenvironment is a heterogeneous entity. Gene expression analysis allows us to perform comprehensive immunoprofiling and may assist in…”
Get full text
Journal Article -
2
Application of MLST and pilus gene sequence comparisons to investigate the population structures of Actinomyces naeslundii and Actinomyces oris
Published in PloS one (30-06-2011)“…Actinomyces naeslundii and Actinomyces oris are members of the oral biofilm. Their identification using 16S rRNA sequencing is problematic and better achieved…”
Get full text
Journal Article -
3
Cripto-1 vaccination elicits protective immunity against metastatic melanoma
Published in Oncoimmunology (03-05-2016)“…Metastatic melanoma is a fatal disease that responds poorly to classical treatments but can be targeted by T cell-based immunotherapy. Cancer vaccines have the…”
Get full text
Journal Article -
4
Bacillus globigii cell size is influenced by variants of the quorum sensing peptide extracellular death factor
Published in Antonie van Leeuwenhoek (2014)“…Toxin-antitoxin modules are necessary for the mode of action of several antibiotics. One of the most studied toxin-antitoxin modules is the quorum…”
Get full text
Journal Article -
5
Effects of environmental temperature on saliva flow rate and secretion of protein, amylase and mucin 5B
Published in Archives of oral biology (01-01-2020)“…•Short exposure (10 min) to different temperatures leads to changes in saliva.•Saliva flow rate increases with decreasing temperature.•Exposure to cold (4 °C)…”
Get full text
Journal Article -
6
Effect of salivary factors on the susceptibility of hydroxyapatite to early erosion
Published in Caries research (01-12-2011)“…Salivary pellicle is known to reduce the erosion of enamel and differences in the level of protection exist between individual saliva sources, but which…”
Get more information
Journal Article -
7
Immunohistochemical Detection of Salivary Agglutinin/gp-340 in Human Parotid, Submandibular, and Labial Salivary Glands
Published in Journal of dental research (01-02-2002)“…Salivary agglutinin is a Streptococcus mutans binding protein and a member of the scavenger receptor cysteine-rich superfamily. It is identical to lung gp-340…”
Get full text
Journal Article -
8
Coexpressed Catalase Protects Chimeric Antigen Receptor-Redirected T Cells as well as Bystander Cells from Oxidative Stress-Induced Loss of Antitumor Activity
Published in The Journal of immunology (1950) (15-01-2016)“…Treatment of cancer patients by adoptive T cell therapy has yielded promising results. In solid tumors, however, T cells encounter a hostile environment, in…”
Get full text
Journal Article -
9
Self-Delivering RNAi Targeting PD-1 Improves Tumor-Specific T Cell Functionality for Adoptive Cell Therapy of Malignant Melanoma
Published in Molecular therapy (06-06-2018)“…Adoptive cell therapy (ACT) is becoming a prominent alternative therapeutic treatment for cancer patients relapsing on traditional therapies. In parallel,…”
Get full text
Journal Article -
10
Interaction of the salivary low-molecular-weight mucin (MG2) with Actinobacillus actinomycetemcomitans
Published in Antonie van Leeuwenhoek (01-07-1996)“…Periodontitis is associated with the presence of certain Gram-negative bacteria in the oral cavity, among these Actinobacillus actinomycetemcomitans. In order…”
Get full text
Journal Article -
11
Methylcholanthrene-Induced Sarcomas Develop Independently from NOX2-Derived ROS
Published in PloS one (15-06-2015)“…Reactive oxygen species (ROS) produced by the inducible NADPH oxidase type 2 (NOX2) complex are essential for clearing certain infectious organisms but may…”
Get full text
Journal Article -
12
DAI (DLM-1/ZBP1) as a Genetic Adjuvant for DNA Vaccines That Promotes Effective Antitumor CTL Immunity
Published in Molecular therapy (01-03-2011)“…DNA vaccination is an attractive approach to induce antigen-specific cytotoxic CD8+ T lymphocytes (CTLs), which can mediate protective antitumor immunity. The…”
Get full text
Journal Article -
13
Renal cell carcinoma escapes NK cell‐mediated immune surveillance through the downregulation of DNAM‐1
Published in Cancer communications (London, England) (01-07-2023)“…Abbreviations NK Natural killer RCC Renal cell carcinoma ccRCC clear cell Renal cell carcinoma DNAM-1 DNAX accessory molecule-1 PVR Poliovirus receptor…”
Get full text
Journal Article -
14
NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses
Published in Human vaccines & immunotherapeutics (01-10-2013)“…DNA vaccines have been shown to elicit tumor-protective cytotoxic T lymphocyte (CTL) immunity in preclinical models, but have shown limited efficacy in cancer…”
Get full text
Journal Article -
15
-
16
Cripto-1 vaccination elicits protective immune response to metastatic breast cancer and breast CSC
Published in SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2017)Get full text
Conference Proceeding -
17
Saliva diagnostics: a summary of the expanded possibilities
Published in Nederlands tijdschrift voor tandheelkunde (09-10-2020)“…In hospitals, blood is still the gold standard in diagnostics, but outside hospitals saliva is used more and more. Collecting saliva is not invasive and is…”
Get more information
Journal Article -
18
Harnessing DNA-induced immune responses for improving cancer vaccines
Published in Human vaccines & immunotherapeutics (01-11-2012)“…DNA vaccines have emerged as an attractive strategy to promote protective cellular and humoral immunity against the encoded antigen. DNA vaccines are easy to…”
Get full text
Journal Article -
19
Correction to: Genetic engineering of human NK cells to express CXCR2 improves migration to renal cell carcinoma
Published in Journal for immunotherapy of cancer (06-11-2017)Get full text
Journal Article -
20
Influence of the blood group reactive substances in saliva on the aggregation of Streptococcus rattus
Published in Antonie van Leeuwenhoek (01-02-1990)“…The interaction of blood group reactive substances in saliva with bacteria was investigated by testing saliva from persons with different blood groups in a…”
Get full text
Journal Article