Search Results - "Ligler, Frances"

Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells by Chen, Qian, Hu, Quanyin, Dukhovlinova, Elena, Chen, Guojun, Ahn, Sarah, Wang, Chao, Ogunnaike, Edikan A., Ligler, Frances S., Dotti, Gianpietro, Gu, Zhen

“…Chimeric antigen receptor (CAR)‐redirected T lymphocytes (CAR T cells) show modest therapeutic efficacy in solid tumors. The desmoplastic structure of the…”
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Perspective on Optical Biosensors and Integrated Sensor Systems by Ligler, Frances S

“…Optical biosensors have begun to move from the laboratory to the point of use. This trend will be accelerated by new concepts for molecular recognition,…”
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Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells by Agarwalla, Pritha, Ogunnaike, Edikan A., Ahn, Sarah, Froehlich, Kristen A., Jansson, Anton, Ligler, Frances S., Dotti, Gianpietro, Brudno, Yevgeny

“…Despite their clinical success, chimeric antigen receptor (CAR)-T cell therapies for B cell malignancies are limited by lengthy, costly and labor-intensive ex…”
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Review of analytical performance of COVID-19 detection methods by Giri, Basant, Pandey, Shishir, Shrestha, Retina, Pokharel, Krisha, Ligler, Frances S., Neupane, Bhanu B.

“…In the recent SARS-CoV-2 pandemic, public health experts have emphasized testing, tracking infected people, and tracing their contacts as an effective strategy…”
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Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery by Yu, Jicheng, Yuqi Zhang, Yanqi Ye, Rocco DiSanto, Wujin Sun, Davis Ranson, Frances S. Ligler, John B. Buse, Zhen Gu

“…A glucose-responsive “closed-loop” insulin delivery system mimicking the function of pancreatic cells has tremendous potential to improve quality of life…”
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Transformable liquid-metal nanomedicine by Lu, Yue, Hu, Quanyin, Lin, Yiliang, Pacardo, Dennis B., Wang, Chao, Sun, Wujin, Ligler, Frances S., Dickey, Michael D., Gu, Zhen

“…To date, numerous inorganic nanocarriers have been explored for drug delivery systems (DDSs). However, the clinical application of inorganic formulations has…”
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Lighting Up Biosensors: Now and the Decade To Come by Ligler, Frances S, Gooding, J. Justin

“…Optical biosensors are defined as portable optical devices that use biorecognition molecules to interrogate a sample for the presence of a target. The…”
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Programmable nanomedicine: synergistic and sequential drug delivery systems by Pacardo, Dennis B, Ligler, Frances S, Gu, Zhen

“…Recent developments in nanomedicine for the cancer therapy have enabled programmable delivery of therapeutics by exploiting the stimuli-responsive properties…”
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Synthetic beta cells for fusion-mediated dynamic insulin secretion by Chen, Zhaowei, Wang, Jinqiang, Sun, Wujin, Archibong, Edikan, Kahkoska, Anna R, Zhang, Xudong, Lu, Yue, Ligler, Frances S, Buse, John B, Gu, Zhen

“…Synthetic beta cells were fabricated through 'vesicles-in-vesicle' liposomal superstructures equipped with glucose-sensing and membrane-fusion machinery, thus…”
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Evanescent wave fluorescence biosensors: Advances of the last decade by Taitt, Chris Rowe, Anderson, George P., Ligler, Frances S.

“…Biosensor development has been a highly dynamic field of research and has progressed rapidly over the past two decades. The advances have accompanied the…”
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Time-Dependent Model for Fluid Flow in Porous Materials with Multiple Pore Sizes by Cummins, Brian M, Chinthapatla, Rukesh, Ligler, Frances S, Walker, Glenn M

“…An understanding of fluid transport through porous materials is critical for the development of lateral flow assays and analytical devices based on paper…”
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Forty years of advances in optical biosensors—are “autonomous” biosensors in our future? by Ligler, Frances S., Ligler, George T.

“…Optical biosensors have employed at least three distinct system architectures over the last 40 years, moving from “sample in-answer out” systems to completely…”
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Interpenetrating networks based on gelatin methacrylamide and PEG formed using concurrent thiol click chemistries for hydrogel tissue engineering scaffolds by Daniele, Michael A, Adams, André A, Naciri, Jawad, North, Stella H, Ligler, Frances S

“…Abstract The integration of biological extracellular matrix (ECM) components and synthetic materials is a promising pathway to fabricate the next generation of…”
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Point-of-care diagnostics for niche applications by Cummins, Brian M, Ligler, Frances S, Walker, Glenn M

“…Point-of-care or point-of-use diagnostics are analytical devices that provide clinically relevant information without the need for a core clinical laboratory…”
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Platelet‐Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury by Su, Teng, Huang, Ke, Ma, Hong, Liang, Hongxia, Dinh, Phuong‐Uyen, Chen, Justin, Shen, Deliang, Allen, Tyler A., Qiao, Li, Li, Zhenhua, Hu, Shiqi, Cores, Jhon, Frame, Brianna N., Young, Ashlyn T., Yin, Qi, Liu, Jiandong, Qian, Li, Caranasos, Thomas G., Brudno, Yevgeny, Ligler, Frances S., Cheng, Ke

“…Cardiovascular disease is the leading cause of mortality worldwide. While reperfusion therapy is vital for patient survival post‐heart attack, it also causes…”
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Enhancement of Bone Regeneration Through the Converse Piezoelectric Effect, A Novel Approach for Applying Mechanical Stimulation by Carter, Amber, Popowski, Kristen, Cheng, Ke, Greenbaum, Alon, Ligler, Frances S, Moatti, Adele

“…Serious bone injuries have devastating effects on the lives of patients including limiting working ability and high cost. Orthopedic implants can aid in…”
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Fibrin Nanoparticles Coupled with Keratinocyte Growth Factor Enhance the Dermal Wound-Healing Rate by Muhamed, Ismaeel, Sproul, Erin P, Ligler, Frances S, Brown, Ashley C

“…Expediting the wound-healing process is critical for patients chronically ill from nonhealing wounds and diseases such as hemophilia or diabetes or who have…”
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Microfabricated blood vessels undergo neoangiogenesis by DiVito, Kyle A, Daniele, Michael A, Roberts, Steven A, Ligler, Frances S, Adams, André A

“…Abstract The greatest ambition and promise of tissue engineering is to manufacture human organs. Before “made-to-measure” tissues can become a reality [1–3] ,…”
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Cardiac Stem Cell Patch Integrated with Microengineered Blood Vessels Promotes Cardiomyocyte Proliferation and Neovascularization after Acute Myocardial Infarction by Su, Teng, Huang, Ke, Daniele, Michael A, Hensley, Michael Taylor, Young, Ashlyn T, Tang, Junnan, Allen, Tyler A, Vandergriff, Adam C, Erb, Patrick D, Ligler, Frances S, Cheng, Ke

“…Cardiac stem cell (CSC) therapy has shown preclinical and clinical evidence for ischemic heart repair but is limited by low cellular engraftment and survival…”
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Three-dimensional imaging of intact porcine cochlea using tissue clearing and custom-built light-sheet microscopy by Moatti, Adele, Cai, Yuheng, Li, Chen, Sattler, Tyler, Edwards, Laura, Piedrahita, Jorge, Ligler, Frances S, Greenbaum, Alon

“…Hearing loss is a prevalent disorder that affects people of all ages. On top of the existing hearing aids and cochlear implants, there is a growing effort to…”
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