Search Results - "Lightstone, L"

Minimising steroids in lupus nephritis – will B cell depletion pave the way? by Lightstone, L

“…The aim of this review is to briefly explore how steroids came to be a presumed adjunct to all treatment regimens for lupus nephritis, despite being the main…”
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Severe pre-eclampsia and hypertensive crises by Arulkumaran, N., MRCP, Lightstone, L., PhD

“…Hypertensive disorders of pregnancy are one of the leading causes of peripartum morbidity and mortality globally. Hypertensive disease in pregnancy is…”
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Tacrolimus is an effective treatment for lupus nephritis in pregnancy by Webster, P, Wardle, A, Bramham, K, Webster, L, Nelson-Piercy, C, Lightstone, L

“…Lupus nephritis during pregnancy increases morbidity and mortality for mother and baby. Flares are difficult to treat as many therapeutic options are…”
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Renoprotective strategies in lupus nephritis: beyond immunosuppression by Griffin, B, Lightstone, L

“…Lupus nephritis needs to be diagnosed promptly and treated specifically with appropriate immunosuppression. However, all patients with lupus nephritis have by…”
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PO.5.114 Online education significantly improved rheumatologists’ knowledge of the burden of lupus nephritis and appropriate treatment strategies for patients by Bell, E, Calle, M, Lightstone, L

“…Background/purposeLupus nephritis (LN) is the most common severe manifestation of SLE and can progress to end stage kidney disease within 15 years of diagnosis…”
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European consensus statement on the terminology used in the management of lupus glomerulonephritis by Gordon, C, Jayne, D, Pusey, C, Adu, D, Amoura, Z, Aringer, M, Ballerin, J, Cervera, R, Calvo-Alén, J, Chizzolini, C, Dayer, JM, Doria, A, Ferrario, F, Floege, J, Guillevin, L, Haubitz, M, Hiepe, F, Houssiau, F, Lesavre, P, Lightstone, L, Meroni, PL, Meyer, O, Moulin, B, O’Reilly, K, Praga, M, Schulze-Koops, H, Sinico, RA, Smith, KGC, Tincani, A, Vasconcelos, C, Hughes, G

“…Systemic lupus erythematosus (SLE) is a complex, multisystem autoimmune disorder, which often involves referral to multiple medical specialists. Lupus…”
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The exaggerated inflammatory response in Behçet's syndrome: identification of dysfunctional post‐transcriptional regulation of the IFN‐γ/CXCL10 IP‐10 pathway by Ambrose, N., Khan, E., Ravindran, R., Lightstone, L., Abraham, S., Botto, M., Johns, M., Haskard, D. O.

“…Summary The mechanisms underlying the exaggerated inflammatory response in Behçet's syndrome (BS) remain poorly understood. We investigated the response of…”
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Urinary proteomic profiles distinguish between active and inactive lupus nephritis by MOSLEY, K, TAM, F. W. K, EDWARDS, R. J, CROZIER, J, PUSEY, C. D, LIGHTSTONE, L

“…Key aims of the treatment of lupus nephritis (LN) are to induce and maintain remission with minimal side effects. However, assessing ongoing renal inflammatory…”
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Analysis of HLA-G expression in renal tissue in lupus nephritis: a pilot study by Foschi, V, Bortolotti, D, Doyle, A F, Stratigou, V, Stephens, L, Trivedi, P, Rinaldi, R, Padovan, M, Bortoluzzi, A, Lightstone, L, Cairns, T D, Botto, M, Cook, T H, Rizzo, R, Govoni, M, Pickering, M C

“…Background The study aimed to investigate whether HLA-G antigen is expressed in the kidneys of patients affected by lupus nephritis (LN) and whether its…”
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Natural regulatory T cells: number and function are normal in the majority of patients with lupus nephritis by Yates, J, Whittington, A, Mitchell, P, Lechler, R.I, Lightstone, L, Lombardi, G

“…CD4⁺ CD25⁺ regulatory T cells have been shown to be a vital component of the mechanisms that prevent autoreactivity in mice and also in humans. Previous…”
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POS-234 PREGNANCY-ASSOCIATED PROGRESSION OF CHRONIC KIDNEY DISEASE: DEVELOPMENT OF A CLINICAL PREDICTIVE TOOL by RALSTON, E., Bramham, K., Clery, A., Wang, Y., Wiles, K., Blakey, H., Lipkin, G., Hall, M., Lightstone, L., Chappell, L., Webster, P., Carr, S.

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P06 OFATUMUMAB FOR B CELL DEPLETION THERAPY IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS WHO ARE INTOLERANT OF RITUXIMAB by McAdoo, S., Masoud, S., Bedi, R., Cairns, T., Lightstone, L.

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Prevalence of chronic kidney disease in South Asian and Black minorities: findings from a population based screening study in London, UK by Roderick, P., Lightstone, L., Harris, S., Lapsley, M., Dockrell, M., Lim, E., Chambers, J., Kooner, J. S.

“…Baseline assessment included renal function (serum creatinine converted to estimated glomerular filtration rate using 4 variable MDRD equations) and single…”
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Quinine-induced immune thrombocytopenic purpura followed by hemolytic uremic syndrome by Glynne, Paul, Salama, Alan, Chaudhry, Afzal, Swirsky, David, Lightstone, Liz

“…Immune thrombocytopenic purpura (ITP) mediated by quinine-dependent platelet reactive antibodies is well recognized. More recently there have been a number of…”
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Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study by Howard, Luke, Abel, K, Altmann, D, Angyal, A, Ashworth, M, Assefa-Kebede, H, Baldry, E, Baldwin, D, Barratt, S, Bishop, L, Broome, M, Brown, M, Burns, G, Chetham, L, Choudhury, G, Coburn, Z, Cole, J, Connor, L, Coupland, C, Cross, A, Dalton, M, Davies, G A, Deakin, B, Defres, S, Diver, S, Dobson, S L, Drain, S, Fairbairn, S, Glossop, J, Greenhalgh, A, Gupta, A, Haggar, A, Harris, V, Harrison, E M, Hart, N, Heller, S, Hosseini, A, Hufton, E, Hussell, T, Ient, A, Ingram, L, Jacob, J, Johnston, D, Kausar, Z, Kelly, S, Khan, F, Korszun, A, Kwan, J, Laing, C, Lamlum, H, Lawrie, A, Lim, L, Lipman, M, Mackay, C, Man, W, Mayet, J, McAuley, H J C, McCann, G P, Mcgarvey, L, McGinness, J, McGuinness, H, McIvor, E, McNarry, M, Mitchell, J, Mohamed, A, Molyneaux, P L, Newell, H, Nicoll, D, Openshaw, P J M, Paradowski, K, Pariante, C, Pendlebury, J, Plekhanova, T, Quint, J, Qureshi, H, Rahman, N, Richardson, M, Rowland, M J, Russell, E, Sage, E K, Shaw, V, Southern, D, Spencer, L G, Stadon, L, Stockley, J, Storrie, A, Summers, C, Taylor, C, Turtle, L, Ugwuoke, R, Wall, E, Watson, J, Welch, C, Wilkinson, D, Williams-Howard, S A, Willis, G, Witham, M, Woods, J, Yasmin, S, Yousuf, A J

“…The impact of COVID-19 on physical and mental health and employment after hospitalisation with acute disease is not well understood. The aim of this study was…”
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Glomerular endotheliosis in normal pregnancy and pre‐eclampsia by Swiet, M, Lightstone, L.

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Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study by Fuld, J, Jenkins, R G, Man, W D-C, Openshaw, P J M, Scott, J T, Quint, J, Thorpe, M, Poinasamy, K, Harrison, E M, Ainsworth, M, Amoils, S, Armstrong, L, Atkin, C, Bain, S, Bates, A, Beckett, P, Bennett, K, Betts, S, Bhui, K, Brown, V, Buckley, P, Carr, C, Childs, C, Choudhury, N, Clohisey, S, Coakley, G, Cosier, T, Cuthbertson, D, Daly, P, Davies, G A, Davies, K, Dowling, R, Drury, K, Dunleavy, A, Evans, H, Evans, R, Finch, J, Fletcher, S, Francis, S, Frankel, A, Fu, X, Gooptu, B, Gregory, R, Hadley, K, Hall, L, Hanley, N A, Hazeldine, J, Heeley, C, Hiwot, T, Ismail, K, James, W Y, Jones, G, Kanellakis, N, Kelly, S, Kemp, G, Knight, S, Laing, C, Lea, A, Lingford-Hughes, A, Lota, H, Lye, A, Majeed, N, Mariveles, M, McArdle, A, McGarvey, L, McGinness, J, McGuinness, H, Monteiro, W, Needham, R, Neill, P, Newton-Cox, A, Noonan, M J, Norman, C, Nyaboko, J, O'Brien, L, Ostermann, M, Papineni, P, Patel, M, Powell, N, Price, L, Propescu, J, Rangeley, J, Redwood, D, Ross, A, Rossdale, J, Rowland, J, Sharma, M, Shaw, A, Shaw, K, Singh, S, Smith, D, Sykes, R, Thompson, A A R, Tomlinson, J, Tripp, K A, Ventura, M, Wight, A, Wilkinson, D, Willicombe, M, Young, S

“…No effective pharmacological or non-pharmacological interventions exist for patients with long COVID. We aimed to describe recovery 1 year after hospital…”
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Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids by Condon, Marie B, Ashby, Damien, Pepper, Ruth J, Cook, H Terence, Levy, Jeremy B, Griffith, Megan, Cairns, Tom D, Lightstone, Liz

“…Lupus nephritis (LN) is a serious complication of systemic lupus erythematosus (SLE). All current treatment regimens include oral steroids, which are…”
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Glomerular endotheliosis in normal pregnancy and pre‐eclampsia by Lindheimer, Marshall D, Mahowald, Mary B

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Lesson Of The Week: Cholesterol Emboli Syndrome by Dupont, Peter J., Lighstone, Liz, Clutterbuck, Elaine J., Gaskin, Gillian, Pusey, Charles D., Cook, Terry, Warrens, Anthony N.

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