Search Results - "Lightfoot, Stanley A."
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The Effect of Diet and Exercise on Intestinal Integrity and Microbial Diversity in Mice
Published in PloS one (08-03-2016)“…The gut microbiota is now known to play an important role contributing to inflammatory-based chronic diseases. This study examined intestinal…”
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Brief Report: Dclk1 Deletion in Tuft Cells Results in Impaired Epithelial Repair After Radiation Injury
Published in Stem cells (Dayton, Ohio) (01-03-2014)“…The role of Dclk1+ tuft cells in the replacement of intestinal epithelia and reestablishing the epithelial barrier after severe genotoxic insult is completely…”
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4-Hydroxy-2-Nonenal Mediates Genotoxicity and Bystander Effects Caused by Enterococcus faecalis –Infected Macrophages
Published in Gastroenterology (New York, N.Y. 1943) (01-03-2012)“…Background & Aims Enterococcus faecalis is a human intestinal commensal that produces extracellular superoxide and promotes chromosome instability via…”
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Novel ovarian cancer maintenance therapy targeted at mortalin and mutant p53
Published in International journal of cancer (15-08-2020)“…Current ovarian cancer maintenance therapy is limited by toxicity and no proven impact on overall survival. To study a maintenance strategy targeted at…”
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Flaxseed but not flaxseed oil prevented the rise in serum cholesterol due to ovariectomy in the Golden Syrian hamsters
Published in Journal of medicinal food (01-03-2011)“…This study was designed to investigate whether flaxseed oil (FO) exerts hypocholesterolemic effects similar to ground whole flaxseed (WF) and to gain insight…”
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Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism
Published in Oncotarget (10-11-2015)“…Tumor stem cell marker Doublecortin-like kinase1 (DCLK1) is upregulated in several solid tumors. The role of DCLK1 in hepatocellular carcinoma (HCC) is…”
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Complementary Targeting of Rb Phosphorylation and Growth in Cervical Cancer Cell Cultures and a Xenograft Mouse Model by SHetA2 and Palbociclib
Published in Cancers (17-05-2020)“…Cervical cancer is caused by high-risk human papillomavirus (HPV) types and treated with conventional chemotherapy with surgery and/or radiation. HPV E6 and E7…”
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Colon Macrophages Polarized by Commensal Bacteria Cause Colitis and Cancer through the Bystander Effect
Published in Translational oncology (2013)“…Abstract Intestinal commensal bacteria have recently been shown to trigger macrophages to produce diffusible clastogens (or chromosome-breaking factors)…”
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TNF-α Mediates Macrophage-Induced Bystander Effects through Netrin-1
Published in Cancer research (Chicago, Ill.) (15-10-2012)“…Macrophage-induced bystander effects have been implicated as an important mediator of chromosomal instability and colon cancer triggered by Enterococcus…”
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Evaluation of (99m)Tc-probestin SPECT as a novel technique for noninvasive imaging of kidney aminopeptidase N expression
Published in Molecular pharmaceutics (04-08-2014)“…Aminopeptidase N (APN; CD13; EC 3.4.11.2) is a zinc-dependent membrane-bound exopeptidase that catalyzes the removal of N-terminal amino acids from peptides…”
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Evaluation of 99mTc-Probestin SPECT As a Novel Technique for Noninvasive Imaging of Kidney Aminopeptidase N Expression
Published in Molecular pharmaceutics (04-08-2014)“…Aminopeptidase N (APN; CD13; EC 3.4.11.2) is a zinc-dependent membrane-bound exopeptidase that catalyzes the removal of N-terminal amino acids from peptides…”
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Flaxseed reverses atherosclerotic lesion formation and lowers lipoprotein(a) in ovarian hormone deficiency
Published in Menopause (New York, N.Y.) (01-11-2013)“…OBJECTIVEThe incidence of cardiovascular disease dramatically increases during menopause, and postmenopausal women seek natural alternatives to hormone…”
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White button and shiitake mushrooms reduce the incidence and severity of collagen-induced arthritis in dilute brown non-agouti mice
Published in The Journal of nutrition (01-01-2011)“…Exotic mushrooms have been used in ancient Chinese medicine due to their immunomodulatory properties for the treatment and/or prevention of chronic diseases…”
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Flaxseed reduces plasma cholesterol and atherosclerotic lesion formation in ovariectomized Golden Syrian hamsters
Published in Atherosclerosis (01-04-2004)“…Background: Dietary modification contributes significantly in reducing cardiovascular disease (CVD) risk factors including lowering cholesterol and…”
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Soy isoflavones prevent ovariectomy-induced atherosclerotic lesions in Golden Syrian hamster model of postmenopausal hyperlipidemia
Published in Menopause (New York, N.Y.) (01-07-2003)“…OBJECTIVESoy isoflavones, as dietary supplements, may reduce the formation of atherosclerotic lesions that increase in women after menopause. The objectives of…”
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Involvement of capsaicin-sensitive sensory neurons in stress-induced gastroduodenal mucosal injury in rats
Published in Digestive diseases and sciences (01-04-2000)“…The pathogenesis of stress-induced gastroduodenal mucosal injury is complex and incompletely understood. The aim of this investigation was to examine the…”
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Exercise ameliorates high fat diet induced intestinal inflammation
Published in The FASEB journal (01-04-2013)“…Abstract only Oxidative stress and inflammation have emerged over the past decade as key features in chronic disease. Research has consistently supported the…”
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Evaluation of 99m Tc-Probestin SPECT As a Novel Technique for Noninvasive Imaging of Kidney Aminopeptidase N Expression
Published in Molecular pharmaceutics (04-08-2014)Get full text
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Dclk1 Deletion in Tuft Cells Results in Impaired Epithelial Repair After Radiation Injury
Published in Stem cells (Dayton, Ohio) (01-03-2014)“…The role of Dclk1 + tuft cells in the replacement of intestinal epithelia and reestablishing the epithelial barrier after severe genotoxic insult is completely…”
Get full text
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