Search Results - "Lifshitz, Ziv"
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Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal
Published in Proceedings of the National Academy of Sciences - PNAS (19-02-2013)“…Legionella and Coxiella are intracellular pathogens that use the virulence-related Icm/Dot type-IVB secretion system to translocate effector proteins into host…”
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Identification of Legionella pneumophila Effectors Regulated by the LetAS-RsmYZ-CsrA Regulatory Cascade, Many of Which Modulate Vesicular Trafficking
Published in Journal of Bacteriology (01-02-2014)“…Legionella pneumophila, the causative agent of Legionnaires' disease, is an intracellular human pathogen that utilizes the Icm/Dot type IVB secretion system to…”
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The Legionella genus core effectors display functional conservation among orthologs by themselves or combined with an accessory protein
Published in Current research in microbial sciences (01-01-2022)“…•The Legionella genus contains nine core effectors.•Three Legionella pneumophila core effectors are required for intracellular growth.•The Legionella genus…”
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In vivo Fitness of Acinetobacter baumannii Strains in Murine Infection Is Associated with International Lineage II-rep-2 and International Lineage III Clones Showing High Case Fatality Rates in Human Infections
Published in Microorganisms (Basel) (04-06-2020)“…We previously reported that the 14-day case fatality rate (CFR) in patients with carbapenem-resistant Acinetobacter baumannii (CRAB) bacteremia varied between…”
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Comparative Study of a Novel Biochemical Assay, the Rapidec Carba NP Test, for Detecting Carbapenemase-Producing Enterobacteriaceae
Published in Journal of clinical microbiology (01-02-2016)“…The novel biochemical test, the Rapidec Carba NP (RCNP), was evaluated using carbapenemase- and non-carbapenemase-producing Enterobacteriaceae isolates. The…”
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Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires
Published in Nature genetics (01-02-2016)“…Gil Segal, Howard Shuman and colleagues sequence the genomes of 38 Legionella species and analyze 5,885 predicted effector proteins. Their analysis identifies…”
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Identification of novel Coxiella burnetii Icm/Dot effectors and genetic analysis of their involvement in modulating a mitogen-activated protein kinase pathway
Published in Infection and immunity (01-09-2014)“…Coxiella burnetii, the causative agent of Q fever, is a human intracellular pathogen that utilizes the Icm/Dot type IVB secretion system to translocate…”
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Does Acinetobacter baumannii Serve as a Source for bla NDM Dissemination into Enterobacteriaceae in Hospitalized Patients?
Published in Microbial drug resistance (Larchmont, N.Y.) (01-03-2018)“…The goal was to study the possibility that Acinetobacter baumannii serve as an epidemiologically significant source for transmission of the bla gene to…”
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Evolution and dissemination of the Klebsiella pneumoniae clonal group 258 throughout Israeli post-acute care hospitals, 2008-13
Published in Journal of antimicrobial chemotherapy (01-08-2017)“…The KPC-producing Klebsiella pneumoniae (KPC-KP) clonal group (CG) 258 has disseminated throughout Israeli post-acute care hospitals (PACHs). The objectives of…”
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Uncovering the Legionella genus effector repertoire - strength in diversity and numbers
Published in Nature genetics (11-01-2016)“…Infection by the human pathogen Legionella pneumophila relies on the translocation of ~300 virulence proteins, termed effectors, which manipulate host-cell…”
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