Search Results - "Lifschitz, Adrián"

Role of ABC Transporters in Veterinary Medicine: Pharmaco- Toxicological Implications by Virkel, Guillermo, Ballent, Mariana, Lanusse, Carlos, Lifschitz, Adrián

“…Unlike physicians, veterinary practitioners must deal with a number of animal species with crucial differences in anatomy, physiology and metabolism…”
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Concentration and environmental fate of ivermectin in floodplain wetlands: An ecosystem approach by Mesa, Leticia, Gutiérrez, Ma. Florencia, Montalto, Luciana, Perez, Vanina, Lifschitz, Adrián

“…Ivermectin (IVM) is commonly used for broad control of endo- and ecto- parasites in cattle. In wetlands of the Parana Medio River, cattle has been treated…”
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The herbicide glyphosate is a weak inhibitor of acetylcholinesterase in rats by Larsen, Karen E, Lifschitz, Adrián L, Lanusse, Carlos E, Virkel, Guillermo L

“…Highlights • The inhibitory potency of glyphosate against acetylcholinesterase was studied in rats. • A higher enzyme activity was measured in brain compared…”
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Unravelling drug-drug interactions in pigs: Induction of hepatic cytochrome P450 1A (CYP1A) metabolism after the in-feed medication with the anthelmintic fenbendazole by Ichinose, Paula, Miró, María Victoria, Larsen, Karen, Lifschitz, Adrián, Virkel, Guillermo

“…The anthelmintic fenbendazole (FBZ) undergoes hepatic S‑oxygenation by monooxygenases belonging to the cytochrome P450 (CYP) and flavin-monooxygenase (FMO)…”
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EXPLORING PRECISION-CUT LIVER SLICES FOR COMPARATIVE XENOBIOTIC METABOLISM PROFILING IN SWINE AND CATTLE by Ichinose, Paula, Miró, María Victoria, Viviani, Paula, Herrera, Juan Manuel, Lifschitz, Adrián, Virkel, Guillermo

“…In vitro systems are useful tools for unravelling species differences in xenobiotic metabolism.The current work aimed to validate the technique of…”
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Ivermectin bioaccumulation and transfer through developmental stages in Culex pipiens (Diptera: Culicidae) by Lorente, Camila Jazmín, Mesa, Leticia, Montalto, Luciana, Gutiérrez, María Florencia, Miró, María Victoria, Lifschitz, Adrián

“…Ivermectin (IVM), one of the most widely used antiparasitics in livestock, could enters into the aquatic environment because the treated animal metabolizes…”
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Relationship between pharmacokinetics of fluazuron and its efficacy for controlling Rhipicephalus microplus: A comprehensive evaluation of tick drug uptake by Sarli, Macarena, Miró, María Victoria, Rossner, María Victoria, Gómez, Viviana, Torrents, Jorgelina, Nava, Santiago, Lifschitz, Adrián

“…Relationship between fluazuron (FZN) concentrations in cattle plasma and ticks and its therapeutic efficacy percentage (EP) against Rhipicephalus microplus was…”
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Comparative assessment of different ivermectin and doramectin formulations for mange control in grazing steers by Canton, Candela, Muchiut, Sebastián, Dominguez, María Paula, Lanusse, Carlos, Alvarez, Luis Ignacio, Lifschitz, Adrián

“…Psoroptic mange causes relevant losses of productivity in cattle. Macrocyclic lactones are one of the main pharmacological tools recommended for controlling…”
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Metabolic stability of glyphosate and its environmental metabolite (aminomethylphosphonic acid) in the ruminal content of cattle by Larsen, Karen, Lifschitz, Adrián, Fernández San Juan, Rocío, Virkel, Guillermo

“…Glyphosate (GLY) is one of the most commonly used herbicides worldwide. Both GLY and aminomethylphosphonic acid (AMPA), its main degradation product, may be…”
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Medication with fenbendazole in feed: plasma concentrations and effects on hepatic xenobiotic metabolizing enzymes in swine by Ichinose, Paula, Miró, María Victoria, Larsen, Karen, Lanusse, Carlos, Lifschitz, Adrián, Virkel, Guillermo

“…Fenbendazole (FBZ), a benzymidazole (BZD) anthelmintic drug, is used for in-feed medication in pigs. BZD-containing drugs may induce cytochrome P450 isozymes…”
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Antiviral effect of high-dose ivermectin in adults with COVID-19: A proof-of-concept randomized trial by Krolewiecki, Alejandro, Lifschitz, Adrián, Moragas, Matías, Travacio, Marina, Valentini, Ricardo, Alonso, Daniel F., Solari, Rubén, Tinelli, Marcelo A., Cimino, Rubén O., Álvarez, Luis, Fleitas, Pedro E., Ceballos, Laura, Golemba, Marcelo, Fernández, Florencia, Fernández de Oliveira, Diego, Astudillo, German, Baeck, Inés, Farina, Javier, Cardama, Georgina A., Mangano, Andrea, Spitzer, Eduardo, Gold, Silvia, Lanusse, Carlos

“…There are limited antiviral options for the treatment of patients with COVID-19. Ivermectin (IVM), a macrocyclic lactone with a wide anti-parasitary spectrum,…”
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Rapid method for paraffin embedding of precision-cut liver slices by Herrera, Juan Manuel, Viviani, Paula, Miró, María Victoria, Lifschitz, Adrián Luis, Virkel, Guillermo León

“…Precision-cut liver slices (PCLS) are tissue explants extensively used as an ex vivo model for metabolism and toxicity studies. When in vitro assays are…”
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Effects of acaricides on the activities of monooxygenases in bovine liver microsomes by Larsen, Karen, Ichinose, Paula, Fernández-San Juan, Rocío, Lifschitz, Adrián, Virkel, Guillermo

“…Organophosphates (OPs), pyrethrins and fipronil, are acaricides commonly used in cattle, mainly as pour on formulations. Scant information is available on…”
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Successive treatments with ivermectin (3.15%) to control the tick Rhipicephalus (Boophilus) microplus in cattle: Pharmacokinetic and efficacy assessment by Sarli, Macarena, Miró, María Victoria, Rossner, María Victoria, Nava, Santiago, Lifschitz, Adrián

“…This study aimed to evaluate the pharmacokinetics, the potential accumulation in the body of treated animals and the efficacy of ivermectin long-acting…”
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Combination of bioactive phytochemicals and synthetic anthelmintics: In vivo and in vitro assessment of the albendazole-thymol association by Miró, María Victoria, e Silva, Carolina Rocha, Viviani, Paula, Luque, Sonia, Lloberas, Mercedes, Costa-Júnior, Livio Martins, Lanusse, Carlos, Virkel, Guillermo, Lifschitz, Adrián

“…•The search of novel strategies for anthelmintic control is an urgent need.•Bioactive phytochemicals may improve parasite control.•The metabolism of TML in the…”
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Relationship between pharmacokinetics of ivermectin (3.15%) and its efficacy to control the infestation with the tick Rhipicephalus (Boophilus) microplus in cattle by Nava, Santiago, Rossner, María V., Ballent, Mariana, Mangold, Atilio J., Lanusse, Carlos, Lifschitz, Adrián

“…•Relationship between ivermectin kinetic and control of Rhipicephalus microplus was evaluated.•Variation of ivermectin 3.15 concentration among heifers did not…”
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Curcumin-PVP improves the in vitro efficacy of ivermectin against resistant and susceptible Haemonchus contortus by Encalada-Mena, Lisandro Alberto, López-Arellano, Raquel, López-Arellano, María Eugenia, Mancilla-Montelongo, María Gabriela, Sandoval-Castro, Carlos Alfredo, Olmedo-Juárez, Agustín, Lifschitz, Adrián, Torres-Acosta, Juan Felipe de Jesús

“…Ivermectin (IVM) resistance in parasitic nematodes such as Haemonchus contortus has spurred a search for substances that help to recover its efficacy. One…”
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Phytochemicals in Gastrointestinal Nematode Control: Pharmacokinetic-Pharmacodynamic Evaluation of the Ivermectin plus Carvone Combination by Miró, María Victoria, Costa-Júnior, Livio Martins, Lloberas, Mercedes, Cardozo, Patricia, Lanusse, Carlos, Virkel, Guillermo, Lifschitz, Adrián

“…A wide variety of plant-derived phytochemicals with anthelmintic effects have been described. Most of them have shown activity against parasites in vitro but…”
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The route of administration drastically affects ivermectin activity against small strongyles in horses by Saumell, Carlos, Lifschitz, Adrián, Baroni, Renato, Fusé, Luis, Bistoletti, Mariana, Sagües, Federica, Bruno, Santiago, Alvarez, Gustavo, Lanusse, Carlos, Alvarez, Luis

“…•Ivermectin efficacy was higher after oral compared to the intramuscular treatment.•Ivermectin plasma concentrations were greater after intramuscular…”
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Ivermectin dissipation and movement from feces to soil under field conditions by Iglesias, Lucía Emilia, Saumell, Carlos, Sagüés, Federica, Sallovitz, Juan Manuel, Lifschitz, Adrián Luis

“…The aim of this work was to evaluate the fate of ivermectin (IVM) at two concentrations in cattle feces and its movement to the nearby soil and plants. Feces…”
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