Search Results - "Liew, Sook Yee"
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1
Inhibition and Larvicidal Activity of Phenylpropanoids from Piper sarmentosum on Acetylcholinesterase against Mosquito Vectors and Their Binding Mode of Interaction
Published in PloS one (06-05-2016)“…Aedes aegypti, Aedes albopictus and Culex quinquefasciatus are vectors of dengue fever and West Nile virus diseases. This study was conducted to determine the…”
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2
Cholinesterase inhibitory activity of isoquinoline alkaloids from three Cryptocarya species (Lauraceae)
Published in Bioorganic & medicinal chemistry (15-09-2016)“…[Display omitted] Alzheimer’s disease is the most common form of dementia among older adults. Acetylcholinesterase and butyrylcholinesterase are two enzymes…”
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3
N -Methyl Costaricine and Costaricine, Two Potent Butyrylcholinesterase Inhibitors from Alseodaphne pendulifolia Gamb
Published in International journal of molecular sciences (27-06-2023)“…Studies have been conducted over the last decade to identify secondary metabolites from plants, in particular those from the class of alkaloids, for the…”
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4
A New Compound from Tradescantia spathacea Leaves
Published in Chemistry of natural compounds (01-07-2024)“…The analysis of the constituents of the leaves of Tradescantia spathacea yielded one new phenolic compound, named 3,6-di- tert -butyl-5-ethylphenol ( 1 ),…”
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5
Phenylpropanoids isolated from Piper sarmentosum Roxb. induce apoptosis in breast cancer cells through reactive oxygen species and mitochondrial-dependent pathways
Published in Chemico-biological interactions (05-01-2018)“…The aim of the present study is to isolate bioactive compounds from the roots of Piper sarmentosum and examine the mechanism of action using human breast…”
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Plant Terpenoids as the Promising Source of Cholinesterase Inhibitors for Anti-AD Therapy
Published in Biology (Basel, Switzerland) (14-02-2022)“…Plant-derived terpenes are the prolific source of modern drugs such as taxol, chloroquine and artemisinin, which are widely used to treat cancer and malaria…”
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7
Natural indole butyrylcholinesterase inhibitors from Nauclea officinalis
Published in Phytomedicine (Stuttgart) (15-01-2015)“…Nine monoterpenoid indole alkaloids; naucletine (1), angustidine (2), nauclefine (3), angustine (4), naucline (5), angustoline (6), harmane (7),…”
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8
Subditine, a new monoterpenoid indole alkaloid from bark of Nauclea subdita (Korth.) Steud. induces apoptosis in human prostate cancer cells
Published in PloS one (14-02-2014)“…In this study, a new apoptotic monoterpenoid indole alkaloid, subditine (1), and four known compounds were isolated from the bark of Nauclea subdita. Complete…”
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9
Natural cholinesterase inhibitors from Myristica cinnamomea King
Published in Bioorganic & medicinal chemistry letters (01-08-2016)“…[Display omitted] A new acylphenol, malabaricone E (1) together with the known malabaricones A-C (2–4), maingayones A and B (5 and 6) and maingayic acid B (7)…”
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10
Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study
Published in International journal of molecular sciences (01-02-2016)“…The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product…”
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11
Naucline, a new indole alkaloid from the bark of Nauclea officinalis
Published in Molecules (Basel, Switzerland) (02-04-2012)“…A new indole alkaloid, naucline (1) together with four known alkaloids, angustine (2), angustidine (3), nauclefine (4) and naucletine (5), were isolated from…”
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12
Chemical constituents from Mesua lepidota T. Anderson and their chemotaxonomic significance
Published in Biochemical systematics and ecology (01-06-2024)“…The phytochemical investigation on Mesua lepidota T. Anderson led to the identification of eight Mammea coumarins [lepidotols A-B (1–2), lepidotol E (3),…”
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13
Insecticidal activity and the mechanism of action of three phenylpropanoids isolated from the roots of Piper sarmentosum Roxb
Published in Scientific reports (03-10-2017)“…Hexane, dichloromethane and methanol extracts of the roots of Piper sarmentosum Roxb. were screened for toxicity towards Sitophilus oryzae (L.), Rhyzopertha…”
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14
Phytochemical constituents from the stem barks of Goniothalamus tapis Miq
Published in Biochemical systematics and ecology (01-12-2020)“…Phytochemical investigation on the stem bark of Goniothalamus tapis Miq. led to the isolation of seven known styryl-lactones, 3-acetyl-isoaltholactone (1),…”
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15
Chemical constituents from Cyathostemma wrayi king and their chemophenetic significance
Published in Biochemical systematics and ecology (01-12-2024)“…The phytochemical studies on the bark of Cyathostemma wrayi King resulted in the identification of ten alkaloids consisting of four oxoaporphines; lysicamine…”
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16
Anti-cholinesterase profile of Murraya koenigii (L.) Spreng essential oil and its chemical constituents
Published in Journal of essential oil-bearing plants (Dehra Dun) (02-09-2024)“…Traditionally, Murraya koenigii (L.) Spreng has been used as an ingredient in medicinal formulations. Several studies have reported on the potential of M…”
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17
Targeted Isolation of Antiviral Labdane Diterpenes from the Bark of Neo-uvaria foetida (Annonaceae) using LC-MS/MS-Based Molecular Networking
Published in Journal of natural products (Washington, D.C.) (23-08-2024)“…In the search of new inhibitors for human coronavirus (HCoV), we screened extracts of endemic Annonaceae plants on an assay using a cellular model of Huh-7…”
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18
Morphinan Alkaloids from the Leaves of Alphonsea cylindrica and Their Antibacterial Properties
Published in Planta medica (01-01-2023)“…A phytochemical study has been carried out on CH Cl extract of leaves, resulting in the isolation of three new morphinan alkaloids. They are kinomenine (1: ),…”
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Secondary metabolites from the barks of Garcinia griffithii T. Anderson (Clusiaceae) and their chemophenetic significance
Published in Biochemical systematics and ecology (01-10-2024)“…A total of thirteen compounds consisting of nine xanthones; cowagarcinone C (1), doitunggarcinone C (2), nigrolineaxanthone E (3), nigrolineaxanthone Q (4),…”
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20
IN/I-Methyl Costaricine and Costaricine, Two Potent Butyrylcholinesterase Inhibitors from IAlseodaphne pendulifolia/I Gamb
Published in International journal of molecular sciences (01-06-2023)“…Studies have been conducted over the last decade to identify secondary metabolites from plants, in particular those from the class of alkaloids, for the…”
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