Search Results - "Liew, Li Phing"

Hydroxyurea-Mediated Cytotoxicity Without Inhibition of Ribonucleotide Reductase by Liew, Li Phing, Lim, Zun Yi, Cohen, Matan, Kong, Ziqing, Marjavaara, Lisette, Chabes, Andrei, Bell, Stephen D.

“…In many organisms, hydroxyurea (HU) inhibits class I ribonucleotide reductase, leading to lowered cellular pools of deoxyribonucleoside triphosphates. The…”
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IgA EGFR antibodies mediate tumour killing in vivo by Boross, Peter, Lohse, Stefan, Nederend, Maaike, Jansen, Johannes Hendrik Marco, van Tetering, Geert, Dechant, Michael, Peipp, Matthias, Royle, Louise, Liew, Li Phing, Boon, Louis, van Rooijen, Nico, Bleeker, Wim K., Parren, Paul W. H. I., van de Winkel, Jan G. J., Valerius, Thomas, Leusen, Jeanette H. W.

“…Currently all approved anti‐cancer therapeutic monoclonal antibodies (mAbs) are of the IgG isotype, which rely on Fcgamma receptors (FcγRs) to recruit cellular…”
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Characterization of a sialate-O-acetylesterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid release by NanH, its cognate sialidase by Phansopa, Chatchawal, Kozak, Radoslaw P, Liew, Li Phing, Frey, Andrew M, Farmilo, Thomas, Parker, Jennifer L, Kelly, David J, Emery, Robert J, Thomson, Rebecca I, Royle, Louise, Gardner, Richard A, Spencer, Daniel I R, Stafford, Graham P

“…Tannerella forsythia, a Gram-negative member of the Bacteroidetes has evolved to harvest and utilize sialic acid. The most common sialic acid in humans is a…”
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The interplay of DNA binding, ATP hydrolysis and helicase activities of the archaeal MCM helicase by Liew, Li Phing, Bell, Stephen D

“…The MCM (minichromosome maintenance) proteins of archaea are widely believed to be the replicative DNA helicase of these organisms. Most archaea possess a…”
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Telomere maintenance: all's well that ends well by Liew, Li Phing, Norbury, Chris J

“…The nucleoprotein structures termed telomeres serve to prevent the mis-identification of eukaryotic chromosome ends as sites of DNA damage, but are also among…”
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Caspase-dependent and -independent lipotoxic cell-death pathways in fission yeast by Low, Choon Pei, Shui, Guanghou, Liew, Li Phing, Buttner, Sabrina, Madeo, Frank, Dawes, Ian W, Wenk, Markus R, Yang, Hongyuan

“…Understanding the mechanisms underlying lipid-induced cell death has significant implications in both cell biology and human diseases. Previously, we showed…”
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Effect of a tail piece cysteine deletion on biochemical and functional properties of an epidermal growth factor receptor-directed IgA2m(1) antibody by Brunke, Christina, Lohse, Stefan, Derer, Stefanie, Peipp, Matthias, Boross, Peter, Kellner, Christian, Beyer, Thomas, Dechant, Michael, Royle, Louise, Liew, Li Phing, Leusen, Jeanette H W, Valerius, Thomas

“…Antibodies of human IgA isotype are critical components of the mucosal immune system, but little is known about their immunotherapeutic potential. Compared…”
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Effect of a tail piece cysteine deletion on biochemical and functional properties of an epidermal growth factor receptor-directed IgA2 m(1) antibody by Brunke, Christina, Lohse, Stefan, Derer, Stefanie, Peipp, Matthias, Boross, Peter, Kellner, Christian, Beyer, Thomas, Dechant, Michael, Royle, Louise, Liew, Li Phing, Leusen, Jeanette HW, Valerius, Thomas

“…Antibodies of human IgA isotype are critical components of the mucosal immune system, but little is known about their immunotherapeutic potential. Compared…”
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Apoptosis and lipoapoptosis in the fission yeast Schizosaccharomyces pombe by Low, Choon Pei, Liew, Li Phing, Pervaiz, Shazib, Yang, Hongyuan

“…Yeasts being simple eukaryotes are established genetic systems that are often employed to solve important biological questions. Recently, it has become evident…”
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Ig A EGFR antibodies mediate tumour killing in vivo by Boross, Peter, Lohse, Stefan, Nederend, Maaike, Jansen, Johannes Hendrik Marco, van Tetering, Geert, Dechant, Michael, Peipp, Matthias, Royle, Louise, Liew, Li Phing, Boon, Louis, van Rooijen, Nico, Bleeker, Wim K., Parren, Paul W. H. I., van de Winkel, Jan G. J., Valerius, Thomas, Leusen, Jeanette H. W.

“…Currently all approved anti‐cancer therapeutic monoclonal antibodies (mAbs) are of the IgG isotype, which rely on Fcgamma receptors (FcγRs) to recruit cellular…”
Get full text