Search Results - "Liew, Lee Chuen"

Mesenchymal stem cell-derived extracellular vesicles: a glimmer of hope in treating Alzheimer's disease by Liew, Lee Chuen, Katsuda, Takeshi, Gailhouste, Luc, Nakagama, Hitoshi, Ochiya, Takahiro

“…One of the pathological hallmarks of Alzheimer's disease (AD) is the presence of extracellular plaques resulting from the accumulation of beta-amyloid peptide…”
Get full text

MicroRNA‐493‐5p‐mediated repression of the MYCN oncogene inhibits hepatic cancer cell growth and invasion by Yasukawa, Ken, Liew, Lee Chuen, Hagiwara, Keitaro, Hironaka‐Mitsuhashi, Ai, Qin, Xian‐Yang, Furutani, Yutaka, Tanaka, Yasuhito, Nakagama, Hitoshi, Kojima, Soichi, Kato, Takashi, Ochiya, Takahiro, Gailhouste, Luc

“…Primary hepatic tumors mainly include hepatocellular carcinoma (HCC), which is one of the most frequent causes of cancer‐related deaths worldwide. Thus far,…”
Get full text

Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells by Gailhouste, Luc, Liew, Lee Chuen, Hatada, Izuho, Nakagama, Hitoshi, Ochiya, Takahiro

“…Curative management of pancreatic adenocarcinoma is limited because this malignancy remains resistant to most chemotherapeutic drugs. Strategies that reverse…”
Get full text

Differentiation Therapy by Epigenetic Reconditioning Exerts Antitumor Effects on Liver Cancer Cells by Gailhouste, Luc, Liew, Lee Chuen, Yasukawa, Ken, Hatada, Izuho, Tanaka, Yasuhito, Nakagama, Hitoshi, Ochiya, Takahiro

“…Primary liver tumors are mainly represented by hepatocellular carcinoma (HCC), one of the most aggressive and resistant forms of cancer. Liver tumorigenesis is…”
Get full text

Mending a broken heart: current strategies and limitations of cell-based therapy by Liew, Lee Chuen, Ho, Beatrice Xuan, Soh, Boon-Seng

“…The versatility of pluripotent stem cells, attributable to their unlimited self-renewal capacity and plasticity, has sparked a considerable interest for…”
Get full text

MEG3-derived miR-493-5p overcomes the oncogenic feature of IGF2-miR-483 loss of imprinting in hepatic cancer cells by Gailhouste, Luc, Liew, Lee Chuen, Yasukawa, Ken, Hatada, Izuho, Tanaka, Yasuhito, Kato, Takashi, Nakagama, Hitoshi, Ochiya, Takahiro

“…Numerous studies have described the critical role played by microRNAs (miRNAs) in cancer progression and the potential of these small non-coding RNAs for…”
Get full text

MicroRNA‐124a inhibits endoderm lineage commitment by targeting Sox17 and Gata6 in mouse embryonic stem cells by Liew, Lee Chuen, Gailhouste, Luc, Tan, Geok Chin, Yamamoto, Yusuke, Takeshita, Fumitaka, Nakagama, Hitoshi, Ochiya, Takahiro

“…The role of microRNAs (miRNAs) during mouse early development, especially in endoderm germ layer formation, is largely unknown. Here, via miRNA profiling…”
Get full text

JAK2 as a surface marker for enrichment of human pluripotent stem cells-derived ventricular cardiomyocytes by Liew, Lee Chuen, Poh, Boon Min, An, Omer, Ho, Beatrice Xuan, Lim, Christina Ying Yan, Pang, Jeremy Kah Sheng, Beh, Leslie Y, Yang, Henry He, Soh, Boon-Seng

“…Human pluripotent stem cell (hPSC)-derived cardiomyocytes (CMs) hold great promise for cardiac disease modelling, drug discovery and regenerative medicine…”
Get full text

Epigenetic Reprogramming of Human Hepatoma Cells: A Low-Cost Option for Drug Metabolism Assessment by Gailhouste, Luc, Liew, Lee Chuen, Yasukawa, Ken, Hagiwara, Keitaro, Iwazaki, Norihiko, Yamada, Yasuhiro, Hatada, Izuho, Ochiya, Takahiro

Get full text

Preliminary study on overproduction of reactive oxygen species by neutrophils in diabetes mellitus by Ridzuan, Noridzzaida, John, Cini Mathew, Sandrasaigaran, Pratheep, Maqbool, Maryam, Liew, Lee Chuen, Lim, Jonathan, Ramasamy, Rajesh

“…AIM: To assess the amount and pattern of reactive oxygen species (ROS) production in diabetic patientderived neutrophils.METHODS: Blood samples from type 2…”
Get full text

MSC-derived small extracellular vesicles exert cardioprotective effect through reducing VLCFAs and apoptosis in human cardiac organoid IRI model by Poh, Boon Min, Liew, Lee Chuen, Soh, Yan Ni Annie, Lai, Ruenn Chai, Lim, Sai Kiang, Ho, Ying Swan, Soh, Boon Seng

“…Cardiovascular diseases (CVDs) are the leading cause of death worldwide, accounting for 31% of all deaths globally. Myocardial ischemia-reperfusion injury…”
Get full text

Upregulation of the JAK-STAT pathway promotes maturation of human embryonic stem cell-derived cardiomyocytes by Ho, Beatrice Xuan, Yu, Hongbing, Pang, Jeremy Kah Sheng, Hor, Jin-Hui, Liew, Lee Chuen, Szyniarowski, Piotr, Lim, Christina Ying Yan, An, Omer, Yang, Henry He, Stewart, Colin L., Chan, Woon Khiong, Ng, Shi-Yan, Soh, Boon-Seng

“…The immature characteristics and metabolic phenotypes of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) restrict their applications for disease…”
Get full text

Preliminary study on overproduction of reactive oxygen species by neutrophils in diabetes mellitus by Noridzzaida Ridzuan Cini Mathew John Pratheep Sandrasaigaran Maryam Maqbool Lee Chuen Liew Jonathan Lim Rajesh Ramasamy

“…AIM:To assess the amount and pattern of reactive oxygen species(ROS)production in diabetic patientderived neutrophils.METHODS:Blood samples from type 2…”
Get full text