Search Results - "Lievers, Karin"

A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk by LIEVERS, Karin J. A, BOERS, Godfried H. J, VERHOEF, Petra, DEN HEIJER, Martin, KLUIJTMANS, Leo A. J, VAN DER PUT, Nathalie M. J, TRIJBELS, Frans J. M, BLOM, Henk J

“…Molecular defects in genes encoding enzymes involved in homocysteine metabolism may account for mild hyperhomocysteinemia, an independent and graded risk…”
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Polymorphisms in the Transcobalamin Gene: Association with Plasma Homocysteine in Healthy Individuals and Vascular Disease Patients by Lievers, Karin J.A, Afman, Lydia A, Kluijtmans, Leo A.J, Boers, Godfried H.J, Verhoef, Petra, den Heijer, Martin, Trijbels, Frans J.M, Blom, Henk J

“…Hyperhomocysteinemia is an independent risk factor for cardiovascular disease (CVD). Intracellular vitamin B(12) deficiency may lead to increased plasma total…”
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The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study by Klerk, Mariska, Lievers, Karin J.A, Kluijtmans, Leo A.J, Blom, Henk J, den Heijer, Martin, Schouten, Evert G, Kok, Frans J, Verhoef, Petra

“…Introduction: Elevated plasma homocysteine levels have been associated with increased risk of cardiovascular disease. A 2756A>G polymorphism has been found in…”
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Bioavailability of polyglutamyl folic acid relative to that of monoglutamyl folic acid in subjects with different genotypes of the glutamate carboxypeptidase II gene by Melse-Boonstra, A, Lievers, K.J.A, Blom, H.J, Verhoef, P

“…Background: Before dietary folate is absorbed, polyglutamate folates are deconjugated to monoglutamates by folylpoly-gamma-glutamyl carboxypeptidase in the…”
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Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561c → T) on plasma homocysteine, folate and vitamin B12 levels and its relationship to cardiovascular disease risk by LIEVERS, Karin J. A, KLUIJTMANS, Leo A. J, BOERS, Godfried H. J, VERHOEF, Petra, DEN HEIJER, Martin, TRIJBELS, Frans J. M, BLOM, Henk J

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Genetics of hyperhomocysteinaemia in cardiovascular disease by Lievers, Karin J A, Kluijtmans, Leo A J, Blom, Henk J

“…Homocysteine, a sulphur amino acid, is a branch-point intermediate of methionine metabolism. It can be degraded in the transsulphuration pathway to…”
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Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects by Afman, Lydia A, Lievers, Karin J A, van der Put, Nathalie M J, Trijbels, Frans J M, Blom, Henk J

“…Homocysteine levels are elevated in mothers of neural tube defect (NTD) children, which may be due to a disturbed folate or vitamin B12 metabolism. Vitamin B12…”
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Association of a 31 bp VNTR in the CBS gene with postload homocysteine concentrations in the Framingham Offspring Study by LIEVERS, Karin J. A, KLUIJTMANS, Leo A. J, BLOM, Henk J, WILSON, Peter W, SELHUB, Jacob, ORDOVAS, Jose M

“…Elevated total plasma homocysteine concentrations (tHcy), both fasting and post-methionine load, have been established as risk factors for vascular disease…”
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Cystathionine β-synthase polymorphisms and hyperhomocysteinaemia: an association study by LIEVERS, Karin J. A, KLUIJTMANS, Leo A. J, HEIL, Sandra G, BOERS, Godfried H. J, VERHOEF, Petra, DEN HEIJER, Martin, TRIJBELS, Frans J. M, BLOM, Henk J

“…Hyperhomocysteinaemia is generally accepted as an independent and graded risk factor for both arterial occlusive disease and venous thrombosis. The only way of…”
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Gene–gene interaction between the cystathionine β-synthase 31 base pair variable number of tandem repeats and the methylenetetrahydrofolate reductase 677C>T polymorphism on homocysteine levels and risk for neural tube defects by Afman, Lydia A, Lievers, Karin J.A, Kluijtmans, Leo A.J, Trijbels, Frans J.M, Blom, Henk J

“…Introduction: Most studies showed that mothers of children with NTD have elevated homocysteine levels pointing to a disturbed homocysteine metabolism as a risk…”
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The −323Ins10 Polymorphism for Factor VII Is Not Associated with Coronary Atherosclerosis in Symptomatic Men by Lievers, Karin J.A, Mennen, Louise I, Rattink, Annemieke P, Zwinderman, Aeilko H, Jukema, J.Wouter, Schouten, Evert G, de Maat, Moniek P.M

“…Elevated factor VII coagulant activity (FVII:C) has been associated with an increased risk of ischaemic heart disease, particularly for fatal events. Results…”
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MAJOR HISTOCOMPATIBILITY COMPLEX VARIATION IN THE ARABIAN ORYX by Hedrick, Philip W., Parker, Karen M., Gutiérrez-Espeleta, Gustavo A., Rattink, Annemieke, Lievers, Karin

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MAJOR HISTOCOMPATIBILITY COMPLEX VARIATION IN THE ARABIAN ORYX by Hedrick, Philip W., Parker, Karen M., Gutiérrez‐Espeleta, Gustavo A., Rattink, Annemieke, Lievers, Karin

“… In the 1960s, the Arabian oryx was one of the most endangered species in the world, extinct in the wild and surviving in only a few captive herds. The…”
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MAJOR HISTOCOMPATIBILITY COMPLEX VARIATION IN THE ARABIAN ORYX by Hedrick, Philip W, Parker, Karen M, Gutiérrez-Espeleta, Gustavo A, Rattink, Annemieke, Lievers, Karin

“…In the 1960s, the Arabian oryx was one of the most endangered species in the world, extinct in the wild and surviving in only a few captive herds. The present…”
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Bioavailability of polyglutamyl folic acid relative to that of monoglutamyl folic acid in subjects with different genotypes of the glutamate carboxypeptidase II gene123 by Melse-Boonstra, Alida, Lievers, Karin JA, Blom, Henk J, Verhoef, Petra

“…Before dietary folate is absorbed, polyglutamate folates are deconjugated to monoglutamates by folylpoly-γ-glutamyl carboxypeptidase in the small intestine…”
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Influence of a glutamate carboxypeptidase II ( GCPII) polymorphism (1561C→T) on plasma homocysteine, folate and vitamin B 12 levels and its relationship to cardiovascular disease risk by Lievers, Karin J.A, Kluijtmans, Leo A.J, Boers, Godfried H.J, Verhoef, Petra, den Heijer, Martin, Trijbels, Frans J.M, Blom, Henk J

“…Elevated levels of total homocysteine and low folate in blood are independent and graded risk factors for arterial occlusive disease. An impairment of folate…”
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Betaine-Homocysteine Methyltransferase (BHMT): Genomic Sequencing and Relevance to Hyperhomocysteinemia and Vascular Disease in Humans by Heil, Sandra G., Lievers, Karin J.A., Boers, Godfried H., Verhoef, Petra, den Heijer, Martin, Trijbels, Frans J.M., Blom, Henk J.

“…Elevated homocysteine levels have been associated with arteriosclerosis and thrombosis. Hyperhomocysteinemia is caused by altered functioning of enzymes of its…”
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A 31 bp VNTR in the cystathionine beta-synthase (CBS) gene is associated with reduced CBS activity and elevated post-load homocysteine levels by Lievers, K J, Kluijtmans, L A, Heil, S G, Boers, G H, Verhoef, P, van Oppenraay-Emmerzaal, D, den Heijer, M, Trijbels, F J, Blom, H J

“…Molecular defects in genes encoding enzymes involved in homocysteine metabolism may account for mild hyperhomocysteinaemia, an independent and graded risk…”
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Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C-->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk by Lievers, Karin J A, Kluijtmans, Leo A J, Boers, Godfried H J, Verhoef, Petra, den Heijer, Martin, Trijbels, Frans J M, Blom, Henk J

“…Elevated levels of total homocysteine and low folate in blood are independent and graded risk factors for arterial occlusive disease. An impairment of folate…”
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Cystathionine -synthase polymorphisms and hyperhomocysteinaemia: an association study by Lievers, Karin J A, Kluijtmans, Leo A J, Heil, Sandra G, Boers, Godfried H J, Verhoef, Petra, Martin den Heijer, Trijbels, Frans J M, Blom, Henk J

“…Hyperhomocysteinaemia is generally accepted as an independent and graded risk factor for both arterial occlusive disease and venous thrombosis. The only way of…”
Get full text