Search Results - "Lies, Barbara"

Interstitial cells of Cajal mediate nitrergic inhibitory neurotransmission in the murine gastrointestinal tract by Lies, Barbara, Gil, Víctor, Groneberg, Dieter, Seidler, Barbara, Saur, Dieter, Wischmeyer, Erhard, Jiménez, Marcel, Friebe, Andreas

“…Nitric oxide (NO) is a major inhibitory neurotransmitter in the gastrointestinal (GI) tract. Its main effector, NO-sensitive guanylyl cyclase (NO-GC), is…”
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Dominant role of interstitial cells of Cajal in nitrergic relaxation of murine lower oesophageal sphincter by Groneberg, Dieter, Zizer, Eugen, Lies, Barbara, Seidler, Barbara, Saur, Dieter, Wagner, Martin, Friebe, Andreas

“…Key points Nitric oxide (NO) is an important inhibitory neurotransmitter in the gastrointestinal tract. Oesophageal achalasia may result from impairment of…”
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Cell-Specific Deletion of Nitric Oxide–Sensitive Guanylyl Cyclase Reveals a Dual Pathway for Nitrergic Neuromuscular Transmission in the Murine Fundus by Groneberg, Dieter, Lies, Barbara, König, Peter, Jäger, Ronald, Seidler, Barbara, Klein, Sabine, Saur, Dieter, Friebe, Andreas

“…Background & Aims It is not clear how nitric oxide (NO) released from enteric neurons relaxes gastrointestinal (GI) smooth muscle. In analogy to the vascular…”
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Flavone potently stimulates an apical transporter for flavonoids in human intestinal Caco-2 cells by Lies, Barbara, Martens, Stefan, Schmidt, Sabine, Boll, Michael, Wenzel, Uwe

“…Scope Based on the studies suggesting that active transport mechanisms contribute to the absorption of flavonoids into human intestinal Caco‐2 cells, we here…”
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Nitrergic signalling via interstitial cells of Cajal regulates motor activity in murine colon by Lies, Barbara, Beck, Katharina, Keppler, Jonas, Saur, Dieter, Groneberg, Dieter, Friebe, Andreas

“…Key points Dysregulation of nitric oxide (NO) signalling is associated with GI motility dysfunctions like chronic constipation, achalasia or Hirschsprung's…”
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Correlation of cellular expression with function of NO‐sensitive guanylyl cyclase in the murine lower urinary tract by Lies, Barbara, Groneberg, Dieter, Friebe, Andreas

“…Key points •  Diseases of the lower urinary tract are associated with dysfunctions of cellular mechanisms that regulate smooth muscle tone. Nitric oxide (NO)…”
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Lack of effect of ODQ does not exclude cGMP signalling via NO‐sensitive guanylyl cyclase by Lies, Barbara, Groneberg, Dieter, Gambaryan, Stepan, Friebe, Andreas

“…Background and Purpose Nitric oxide (NO) is known to activate NO‐sensitive guanylyl cyclase (NO‐GC) and to elicit cGMP production. However, NO has also been…”
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Dominant role of interstitial cells of Cajal in nitrergic relaxation of murine lower oesophageal sphincter by Groneberg, Dieter, Zizer, Eugen, Lies, Barbara, Seidler, Barbara, Saur, Dieter, Wagner, Martin, Friebe, Andreas

“…Oesophageal achalasia is a disease known to result from reduced relaxation of the lower oesophageal sphincter (LES). Nitric oxide (NO) is one of the main…”
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Reply by Friebe, Andreas, Groneberg, Dieter, Lies, Barbara

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Reply by Friebe, Andreas, Groneberg, Dieter, Lies, Barbara

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Flavone potently stimulates an apical transporter for flavonoids in human intestinal C aco‐2 cells by Lies, Barbara, Martens, Stefan, Schmidt, Sabine, Boll, Michael, Wenzel, Uwe

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Preserved fertility despite erectile dysfunction in mice lacking the nitric oxide receptor by Groneberg, Dieter, Lies, Barbara, König, Peter, Jäger, Ronald, Friebe, Andreas

“…Key points •  Erectile dysfunction may result from reduced or non‐functional nitric oxide (NO)/cGMP‐mediated signalling. Mice lacking NO synthases are fertile…”
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Modulation of cGMP/cAMP crosstalk on the level of PDE3 in animals lacking NO-sensitive guanylyl cyclase by Friebe, Andreas, Dünnes, Sarah, Nikolaev, Viacheslav, Lies, Barbara, Groneberg, Dieter

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Cell-specific modulation of gastrointestinal NO-induced relaxation by phosphodiesterases by Groneberg, Dieter, Aue, Annemarie, Lies, Barbara, Friebe, Andreas

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A case of chaos? NO causes arrhythmic motor pattern via interstitial cells of Cajal in the murine colon by Beck, Katharina, Groneberg, Dieter, Friebe, Andreas, Lies, Barbara

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Reply: To PMID 23528627 by Friebe, Andreas, Groneberg, Dieter, Lies, Barbara

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Cell type-specific knock out models to unravel NO/cGMP signaling in smooth muscle by Bettaga, Noomen, Groneberg, Dieter, Jäger, Ronald, Lies, Barbara, Friebe, Andreas

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Localization and function of NO-GC in the murine gastrointestinal and lower urinary tract by Lies, Barbara, Groneberg, Dieter, Saur, Dieter, Friebe, Andreas

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Radioimmunoassay for the quantification of cGMP levels in cells and tissues by Jäger, Ronald, Groneberg, Dieter, Lies, Barbara, Bettaga, Noomen, Kümmel, Michaela, Friebe, Andreas

“…Radioimmunoassay is an established method to determine the amount of a specific substance in a given cell or tissue sample. Commercially available RIA or Elisa…”
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Nitrergic relaxation of gastrointestinal smooth muscle: role of interstitial cells of Cajal and smooth muscle cells by Lies, Barbara, Groneberg, Dieter, Saur, Dieter, König, Peter, Friebe, Andreas

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