Search Results - "Liepin'sh, E."

Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels by Dambrova, M, Latkovskis, G, Kuka, J, Strele, I, Konrade, I, Grinberga, S, Hartmane, D, Pugovics, O, Erglis, A, Liepinsh, E

“…Recent studies have revealed strong associations between systemic trimethylamine N-oxide (TMAO) levels, atherosclerosis and cardiovascular risk. In addition,…”
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Risks and benefits of carnitine supplementation in diabetes by Dambrova, M, Liepinsh, E

“…L-carnitine is a very popular food supplement due to its safety profile, antioxidant-type activity and suggested effects on energy metabolism pathways…”
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Loop diuretics decrease the renal elimination rate and increase the plasma levels of trimethylamine‐N‐oxide by Latkovskis, G., Makarova, E., Mazule, M., Bondare, L., Hartmane, D., Cirule, H., Grinberga, S., Erglis, A., Liepinsh, E., Dambrova, M.

“…Aims Trimethylamine‐N‐oxide (TMAO) is a novel cardiovascular risk marker. We explored the association of commonly used cardiovascular medications with TMAO…”
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Dibenzyl(methyl)[γ-(1-piperidyl)propyl]silane hydrooxalate by Erchak, N. P., Kovalenko, V. V., Lenivko, S. M., Pypovski, K., Liepin’sh, E.

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Inhibition of L‐carnitine biosynthesis and transport by methyl‐γ‐butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction by Liepinsh, E, Makrecka‐Kuka, M, Kuka, J, Vilskersts, R, Makarova, E, Cirule, H, Loza, E, Lola, D, Grinberga, S, Pugovics, O, Kalvins, I, Dambrova, M

“…Background and Purpose The important pathological consequences of ischaemic heart disease arise from the detrimental effects of the accumulation of long‐chain…”
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Taregting acylcarnitine content in vascular tissue to attenuate development of atherosclerosis by Vilskersts, R, Kuka, J, Makrecka-Kuka, M, Volska, K, Dambrova, M, Liepinsh, E

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NMR structure of the death domain of the p75 neurotrophin receptor by Liepinsh, Edvards, Ilag, Leopold L., Otting, Gottfried, Ibáñez, Carlos F.

“…The intracellular domain of the p75 neurotrophin receptor (p75ICD) lacks catalytic activity but contains a motif similar to death domains found in the…”
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Synthesis of Pentacoordinated Si-(Morpholiniomethyl)Silanates by Erchak, N., Olszewska, E., Kalvinsh, I., Liepinsh, E., Belyakov, S., Sobolev, A., Arsenyan, P.

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Synthesis of Novel Unsymmetrically Substituted 1,4-Dihydroisonicotinic Acid and its Derivatives by Goba, I., Turovska, B., Belyakov, S., Liepinsh, E.

“…The synthesis of new unsymmetrically substituted 1,4-dihydroisonicotinic acid bearing cyano and acetyl groups in positions 3 and 5 of the heterocycle has been…”
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Thioredoxin Fold as Homodimerization Module in the Putative Chaperone ERp29: NMR Structures of the Domains and Experimental Model of the 51 kDa Dimer by Liepinsh, E., Baryshev, M., Sharipo, A., Ingelman-Sundberg, M., Otting, G., Mkrtchian, S.

“…Background: ERp29 is a ubiquitously expressed rat endoplasmic reticulum (ER) protein conserved in mammalian species. Fold predictions suggest the presence of a…”
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NMR structure of the LCCL domain and implications for DFNA9 deafness disorder by Liepinsh, Edvards, Trexler, Mária, Kaikkonen, Andrei, Weigelt, Johan, Bányai, László, Patthy, László, Otting, Gottfried

“…The LCCL domain is a recently discovered, conserved protein module named after its presence in Limulus factor C, cochlear protein Coch‐5b2 and late gestation…”
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Reactivity of Aziridine-2-Carboxamide (Leakadine) with Nucleophiles in Aqueous Solutions by Aleksis, R., Jaudzems, K., Ivanova, J., Žalubovskis, R., Kalvinsh, I., Liepinsh, E.

“…We describe studies of aziridine-2-carboxamide (Leakadine) reactivity with N-, O-, and S-nucleophiles in aqueous solutions using NMR spectroscopy and chemical…”
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Reactions of 9-Aroyl-3,3,6,6-Tetramethyl-1,2,3,4,5,6,7,8-Octahydroxanthene-1,8-Diones With Hydrazine and Methylhydrazine by Bisenieks, E., Uldrikis, J., Poikans, J., Baumane, L., Petrova, M., Liepinsh, E., Duburs, G.

“…Reactions of 9-aroyl-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8-octahydroxanthene-1,8-diones with hydrazine and methylhydrazine produced cinnoline derivatives. A…”
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Method for the preparation of 4-aryl-3-pyrrolin-2-ones and their 5-bromo derivatives by Vorona, M., Orlova, N., Kuznetsov, E., Vikainis, S., Liepinsh, E., Belyakov, S., Mishnev, A., Veinberg, G.

“…An effective method for the conversion of 1-acetyl-4-phenyl-2-pyrrolidone into 1-acetyl-4-phenyl-3-pyrrolin-2-one by bromination–dehydrobromination with N…”
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Spectral and Quantum-Chemical Study of Nonequivalence of Methylene Protons in 1,4-Dihydropyridine Derivatives by Petrova, M., Muhamadejev, R., Chesnokov, A., Vigante, B., Cekavicus, B., Plotniece, A., Duburs, G., Liepinsh, E.

“…Structural characteristics of 1,4-dihydropyridines influencing the nonequivalence of the diastereotopic methylene protons in substituents at positions 2 and 6…”
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Novel Anti-inflammatory Compound, Artonkin-4'-O-glucoside, from the Leaves of Artocarpus tonkinensis Suppresses Experimentally Induced Arthritis by Dang, D.T.N, Eriste, E, Liepinsh, E, Trinh, T.T, Erlandsson-Harris, H, Sillard, R, Larsson, P

“…Artocarpus tonkinenesis (Moraceae) has been used in Vietnamese traditional medicine for the treatment of backache and joint diseases since many 100 years. We…”
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Synthesis and biological activity of alkylidene-substituted cephems and penams by Potorocina, I., Vorona, M., Shestakova, I., Domracheva, I., Liepinsh, E., Veinberg, G.

“…The condensation of tert -butyl esters of 3-methyl-7-oxoceph-3-em-4-carboxylic and 6-oxopenicillanic acids with a series of…”
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new regioselective synthesis of 2-methoxymethyl-3-oxo-2,3-di-hydro-7H-thiazolo[3,2-a]pyridine-8-carboxylic acid methylamide by Krauze, A, Liepinsh, E, Vilums, M, Duburs, G

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Hydration of proteins. A comparison of experimental residence times of water molecules solvating the bovine pancreatic trypsin inhibitor with theoretical model calculations by Brunne, R M, Liepinsh, E, Otting, G, Wüthrich, K, van Gunsteren, W F

“…A 1 ns trajectory from a molecular dynamics study of 1.4 ns total length was used for a detailed analysis of the residence times of water molecules located…”
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Enzymatic synthesis of amoxicilloic acids by Vorona, M, Veinberg, G, Liepinsh, E, Kažoka, H, Andrejeva, G, Lukevics, E

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