Search Results - "Liepa, Jennifer"
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Largen: A Molecular Regulator of Mammalian Cell Size Control
Published in Molecular cell (20-03-2014)“…Little is known about how mammalian cells maintain cell size homeostasis. We conducted a novel genetic screen to identify cell-size-controlling genes and…”
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p53-Dependent Inhibition of FKHRL1 in Response to DNA Damage through Protein Kinase SGK1
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-2004)“…FKHRL1 (FOXO3a) and p53 are two potent stress-response regulators. Here we show that these two transcription factors exhibit "crosstalk" in vivo. In response…”
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Chk2 Regulates Irradiation-Induced, p53-Mediated Apoptosis in Drosophila
Published in Proceedings of the National Academy of Sciences - PNAS (20-08-2002)“…The tumor suppressor function of p53 has been attributed to its ability to regulate apoptosis and the cell cycle. In mammals, DNA damage, aberrant growth…”
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Fas Receptor Expression in Germinal-Center B Cells Is Essential for T and B Lymphocyte Homeostasis
Published in Immunity (Cambridge, Mass.) (17-10-2008)“…Fas is highly expressed in activated and germinal center (GC) B cells but can potentially be inactivated by misguided somatic hypermutation. We employed…”
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DJ-1, a novel regulator of the tumor suppressor PTEN
Published in Cancer cell (01-03-2005)“…The phosphatidylinositol 3′ kinase (PI3′K) pathway, which regulates cell survival, is antagonized by the PTEN tumor suppressor. The regulation of PTEN is…”
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Fas Receptor Expression in Germinal-Center B Cells Is Essential for T and B Lymphocyte Homeostasis
Published in Immunity (Cambridge, Mass.) (01-10-2008)“…Fas is highly expressed in activated and germinal center (GC) B cells but can potentially be inactivated by misguided somatic hypermutation. We employed…”
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Journal Article