Search Results - "Liemann, Susanne"
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Influence of Amino Acid Substitutions Related to Inherited Human Prion Diseases on the Thermodynamic Stability of the Cellular Prion Protein
Published in Biochemistry (Easton) (16-03-1999)“…Transmissible spongiform encephalopathies (TSEs) are caused by a unique infectious agent which appears to be identical with PrPSc, an oligomeric, misfolded…”
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2
Prion Protein Binds Copper within the Physiological Concentration Range
Published in The Journal of biological chemistry (18-05-2001)“…The prion protein is known to be a copper-binding protein, but affinity and stoichiometry data for the full-length protein at a physiological pH of 7 were…”
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3
Prion protein expression in different species: analysis with a panel of new mAbs
Published in Proceedings of the National Academy of Sciences - PNAS (21-07-1998)“…By immunizing prion knockout mice (Prnp-/-) with recombinant murine prion protein (PrP(c)), we obtained a panel of mAbs specific for murine PrP(c). These mAbs…”
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4
Disulfide Bonding among μ1 Trimers in Mammalian Reovirus Outer Capsid: a Late and Reversible Step in Virion Morphogenesis
Published in Journal of Virology (01-05-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
The Crystal Structure and Ion Channel Activity of Human Annexin II, a Peripheral Membrane Protein
Published in Journal of molecular biology (12-04-1996)“…Annexin II binds in a calcium-dependent manner to acidic phospholipids and is a substrate of some protein kinases. An N-terminally shortened form of human…”
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6
Structure of the Reovirus Membrane-Penetration Protein, μ1, in a Complex with Its Protector Protein, σ3
Published in Cell (25-01-2002)“…Cell entry by nonenveloped animal viruses requires membrane penetration without membrane fusion. The reovirus penetration agent is the outer-capsid protein,…”
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7
Annexins: a novel family of calcium- and membrane-binding proteins in search of a function
Published in Structure (15-03-1995)“…Although the annexins have been extensively studied and much detailed structural information is available, their in vivo function has yet to be established…”
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8
Extremely rapid folding of the C-terminal domain of the prion protein without kinetic intermediates
Published in Nature structural biology (01-06-1999)“…The kinetics of folding of mPrP(121-231), the structured 111-residue domain of the murine cellular prion protein PrP(C), were investigated by stopped-flow…”
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9
Transmissible Spongiform Encephalopathies
Published in Biochemical and biophysical research communications (18-09-1998)“…Scrapie, bovine spongiform encephalopathy (BSE), and the Creutzfeldt-Jakob disease (CJD) belong to a group of lethal neurodegenerative disorders in mammals…”
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10
The Structure of Recombinant Human Annexin VI in Crystals and Membrane-bound
Published in Journal of molecular biology (02-08-1996)“…The crystal structure of calcium-free recombinant human annexin VI was solved at a resolution of 3.2 Å by using the annexin I model for Patterson search and…”
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11
Disulfide bonding among micro 1 trimers in mammalian reovirus outer capsid: a late and reversible step in virion morphogenesis
Published in Journal of virology (01-05-2003)“…We examined how a particular type of intermolecular disulfide (ds) bond is formed in the capsid of a cytoplasmically replicating nonenveloped animal virus…”
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12
Annexin V: the key to understanding ion selectivity and voltage regulation?
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-07-1994)“…Annexin V is a Ca(2+)-dependent membrane-binding protein that forms voltage-dependent Ca2+ channels in phospholipid bilayers and is the first ion channel to be…”
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13
Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3
Published in Cell (25-01-2002)“…Cell entry by nonenveloped animal viruses requires membrane penetration without membrane fusion. The reovirus penetration agent is the outer-capsid protein,…”
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14
Voltage dependent binding of annexin V, annexin VI and annexin VII-core to acidic phospholipid membranes
Published in Biochimica et biophysica acta (04-12-1997)“…Annexin V, VI and VII-core (Δ1–107) are members of the annexin protein family and bind to acidic phospholipid membranes in a calcium dependent manner. They…”
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15
Structural and Functional Characterisation of the Voltage Sensor in the Ion Channel Human Annexin V
Published in Journal of molecular biology (17-05-1996)“…The ion channel properties of human annexin V, a calcium- and phospholipid-binding protein of the annexin family, have been structurally and functionally…”
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16
The Calcium-Dependent Binding of Annexin V to Phospholipid Vesicles Influences the Bilayer Inner Fluidity Gradient
Published in Biochemistry (Easton) (21-07-1998)“…The fluidity of the hydrophobic interior of phospholipid vesicles after calcium-dependent binding of human annexin V (AVH) was studied using EPR spectroscopy…”
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17
Crystal structure of the C-terminal tetrad repeat from synexin (annexin VII) of Dictyostelium discoideum
Published in Journal of molecular biology (01-01-1997)“…Synexin (annexin VII) is a cytosolic Ca 2+-binding protein that promotes membrane fusion and forms voltage-regulated ion channels in artificial and natural…”
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18
Selection and characterization of single chain Fv fragments against murine recombinant prion protein from a synthetic human antibody phage display library
Published in Human antibodies (2000)“…We describe the selection of single chain Fv fragments (scFv) against recombinant murine prion protein (mPrP) from a synthetic human antibody phage display…”
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