Search Results - "Liem, Robert I."
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Development of a Pediatric Cardiology Cardiopulmonary Exercise Testing Database
Published in Pediatric cardiology (01-08-2024)“…Cardiopulmonary exercise testing (CPET) provides clinicians with information vital to the management of pediatric cardiology patients. CPET can also be used to…”
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Adherence to hydroxyurea, health-related quality of life domains, and patients' perceptions of sickle cell disease and hydroxyurea: a cross-sectional study in adolescents and young adults
Published in Health and quality of life outcomes (05-07-2017)“…Sickle cell disease (SCD) patients have impaired domains of health-related quality of life (HRQOL). Hydroxyurea is safe and efficacious in SCD; however,…”
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American Society of Hematology 2019 guidelines for sickle cell disease: cardiopulmonary and kidney disease
Published in Blood advances (10-12-2019)“…Background: Prevention and management of end-organ disease represent major challenges facing providers of children and adults with sickle cell disease (SCD)…”
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Determining the longitudinal validity and meaningful differences in HRQL of the PedsQL™ Sickle Cell Disease Module
Published in Health and quality of life outcomes (12-06-2017)“…Detecting change in health status over time and ascertaining meaningful changes are critical elements when using health-related quality of life (HRQL)…”
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Heart Rate Recovery Is Impaired after Maximal Exercise Testing in Children with Sickle Cell Anemia
Published in The Journal of pediatrics (01-02-2015)“…Objective To examine heart rate recovery (HRR) as an indicator of autonomic nervous system dysfunction after maximal exercise testing in children and young…”
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Transition to adulthood and adult health care for patients with sickle cell disease or cystic fibrosis: Current practices and research priorities
Published in Journal of clinical and translational science (01-10-2018)“…A growing population of adults living with severe, chronic childhood-onset health conditions has created a need for specialized health care delivered by…”
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Balancing exercise risk and benefits: lessons learned from sickle cell trait and sickle cell anemia
Published in Hematology (30-11-2018)“…Development of exercise guidelines for individuals with sickle cell trait (SCT) and sickle cell anemia (SCA) is hampered by the need to weigh the benefits…”
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2019 sickle cell disease guidelines by the American Society of Hematology: methodology, challenges, and innovations
Published in Blood advances (10-12-2019)“…The American Society of Hematology (ASH) convened 5 guideline panels to develop clinical practice recommendations addressing 5 management areas of highest…”
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Technology Access and Smartphone App Preferences for Medication Adherence in Adolescents and Young Adults With Sickle Cell Disease
Published in Pediatric blood & cancer (01-05-2016)“…Background Hydroxyurea is the only Food and Drug Administration approved medication for sickle cell disease (SCD) with short‐ and long‐term benefits for both…”
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Exercise and training in sickle cell disease: Safety, potential benefits, and recommendations
Published in American journal of hematology (01-10-2024)“…Sickle cell disease (SCD) is a genetic disorder characterized by complex pathophysiological mechanisms leading to vaso‐occlusive crisis, chronic pain, chronic…”
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Pediatric Exercise Testing: Value and Implications of Peak Oxygen Uptake
Published in Children (Basel) (24-01-2017)“…Peak oxygen uptake (peak V ˙ O 2 ) measured by clinical exercise testing is the benchmark for aerobic fitness. Aerobic fitness, estimated from maximal…”
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Tricuspid regurgitant jet velocity is associated with hemolysis in children and young adults with sickle cell disease evaluated for pulmonary hypertension
Published in Haematologica (Roma) (01-11-2007)“…From the Division of Hematology, Oncology & Stem Cell Transplant (RIL, AAT); Division of Cardiology (LTY), Childrens Memorial Hospital, Northwestern…”
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Cerebral and skeletal muscle tissue oxygenation during exercise challenge in children and young adults with sickle cell anaemia
Published in British journal of haematology (01-01-2022)“…Summary We used near‐infrared spectroscopy to examine tissue oxygenation (StO2) during exercise in 17 children and young adults with sickle cell anaemia (SCA)…”
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Risk Factors for Neonatal Venous and Arterial Thromboembolism in the Neonatal Intensive Care Unit—A Case Control Study
Published in The Journal of pediatrics (01-04-2018)“…To identify risk factors associated with venous and arterial thrombosis in sick neonates admitted to the neonatal intensive care unit. A case-control study was…”
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Challenges of alloimmunization in patients with haemoglobinopathies
Published in British journal of haematology (01-11-2012)“…Summary Red blood cell (RBC) transfusions can be life‐sustaining in chronic inherited anaemias, such as thalassaemia, and the indications for blood…”
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Heart rate variability associated with acute exercise challenge in children with sickle cell anaemia
Published in British journal of haematology (01-01-2022)“…Summary We examined heart rate variability (HRV) during exercise testing in 20 children with sickle cell anaemia (SCA) and 12 controls. Subjects achieved lower…”
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A Reference Equation for Peak Oxygen Uptake for Pediatric Patients Who Undergo Treadmill Cardiopulmonary Exercise Testing
Published in The American journal of cardiology (01-02-2024)“…Pediatric patients are often referred to cardiopulmonary exercise testing (CPET) laboratories for assessment of exercise-related symptoms. For clinicians to…”
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Reference Values for Cardiorespiratory Fitness in Patients Aged 6 to 18 Years
Published in The Journal of pediatrics (01-01-2024)“…To develop reference values for cardiorespiratory fitness, as quantified by peak oxygen uptake (VO ) and treadmill time, in patients aged 6 through 18 years…”
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Whole-blood transcriptome analysis reveals distinct gene expression signatures in paediatric patients with sickle cell anaemia before and after exercise
Published in British journal of haematology (01-07-2024)“…Sickle cell anaemia (SCA) patients display elevated levels of circulating pro-inflammatory cytokines and endothelial activation markers compared to healthy…”
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Translating exercise benefits in sickle cell disease
Published in Blood (19-12-2019)“…The pathophysiologic basis for reduced fitness in sickle cell disease (SCD) is multifactorial and characterized by impaired oxygen-carrying capacity,…”
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