Search Results - "Liebert, Monica"

Targeted DNA and RNA Sequencing of Paired Urothelial and Squamous Bladder Cancers Reveals Discordant Genomic and Transcriptomic Events and Unique Therapeutic Implications by Hovelson, Daniel H., Udager, Aaron M., McDaniel, Andrew S., Grivas, Petros, Palmbos, Phillip, Tamura, Shuzo, Lazo de la Vega, Lorena, Palapattu, Ganesh, Veeneman, Brendan, El-Sawy, Layla, Sadis, Seth E., Morgan, Todd M., Montgomery, Jeffrey S., Weizer, Alon Z., Day, Kathleen C., Neamati, Nouri, Liebert, Monica, Keller, Evan T., Day, Mark L., Mehra, Rohit, Tomlins, Scott A.

“…Integrated molecular profiling has identified intrinsic expression-based bladder cancer molecular subtypes. Despite frequent histological diversity, robustness…”
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Interleukin-8 is essential for normal urothelial cell survival by Tseng-Rogenski, Stephanie, Liebert, Monica

“…Interleukin-8 (IL-8; CXCL8) has been shown to play a role in multiple cellular processes. Here, we report an additional role of IL-8 as a growth and essential…”
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ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms by Palmbos, Phillip L, Wang, Lidong, Yang, Huibin, Wang, Yin, Leflein, Jacob, Ahmet, McKenzie L, Wilkinson, John E, Kumar-Sinha, Chandan, Ney, Gina M, Tomlins, Scott A, Daignault, Stephanie, Kunju, Lakshmi P, Wu, Xue-Ru, Lotan, Yair, Liebert, Monica, Ljungman, Mats E, Simeone, Diane M

“…Bladder cancer is a common and deadly malignancy but its treatment has advanced little due to poor understanding of the factors and pathways that promote…”
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ADAM15 Is Functionally Associated with the Metastatic Progression of Human Bladder Cancer by Lorenzatti Hiles, Guadalupe, Bucheit, Amanda, Rubin, John R, Hayward, Alexandra, Cates, Angelica L, Day, Kathleen C, El-Sawy, Layla, Kunju, L Priya, Daignault, Stephanie, Lee, Cheryl T, Liebert, Monica, Hussain, Maha, Day, Mark L

“…ADAM15 is a member of a family of catalytically active disintegrin membrane metalloproteinases that function as molecular signaling switches, shed membrane…”
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Erectile function outcome reporting after clinically localized prostate cancer treatment by Burnett, Arthur L, Aus, Gunnar, Canby-Hagino, Edith D, Cookson, Michael S, D'Amico, Anthony V, Dmochowski, Roger R, Eton, David T, Forman, Jeffrey D, Goldenberg, S Larry, Hernandez, Javier, Higano, Celestia S, Kraus, Stephen, Liebert, Monica, Moul, Judd W, Tangen, Catherine, Thrasher, J Brantley, Thompson, Ian

“…In conjunction with the assignment to update the Guidelines for Management of Clinically Localized Prostate Cancer, the American Urological Association…”
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Evaluation of the antitumor activity of dacomitinib in models of human bladder cancer by Grivas, Petros D, Day, Kathleen C, Karatsinides, Andreas, Paul, Alyssa, Shakir, Nazia, Owainati, Iya, Liebert, Monica, Kunju, Lakshmi P, Thomas, Dafydd, Hussain, Maha, Day, Mark L

“…Members of the human epidermal growth factor receptor (HER) family play a significant role in bladder cancer progression and may underlie the development of…”
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Current preclinical models for the advancement of translational bladder cancer research by DeGraff, David J, Robinson, Victoria L, Shah, Jay B, Brandt, William D, Sonpavde, Guru, Kang, Yibin, Liebert, Monica, Wu, Xue-Ru, Taylor, 3rd, John A

“…Bladder cancer is a common disease representing the fifth most diagnosed solid tumor in the United States. Despite this, advances in our understanding of the…”
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MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells by TANAKA, Motoyoshi, KOUL, Dimpy, DAVIES, Michael A, LIEBERT, Monica, STECK, Peter A, GROSSMAN, H. Barton

“…The development and progression of bladder cancer is associated with multiple alterations in the genome, including loss of chromosome 10. Recently, MMAC1/PTEN,…”
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The urothelial glycosaminoglycan layer revisited by Liebert, Monica

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Suppression of 15-hydroxyprostaglandin dehydrogenase messenger RNA concentration, protein expression, and enzymatic activity during human ureteral obstruction by Jerde, Travis J, Mellon, William S, Fischer, Susan M, Liebert, Monica, Bjorling, Dale E, Nakada, Stephen Y

“…Prostanoids produce significant effects in the ureter, particularly in response to obstruction. Ureteral obstruction is associated with increased prostanoid…”
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Relationship among cystectomy, microvessel density and prognosis in stage T1 transitional cell carcinoma of the bladder by Dinney, C P, Babkowski, R C, Antelo, M, Perrotte, P, Liebert, M, Zhang, H Z, Palmer, J, Veltri, R W, Katz, R L, Grossman, H B

“…The selection of therapy for stage T1 bladder cancer is controversial, and reliable biomarkers that identify patients likely to require cystectomy for local…”
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A surgical orthotopic approach for studying the invasive progression of human bladder cancer by Lorenzatti Hiles, Guadalupe, Cates, Angelica L., El-Sawy, Layla, Day, Kathleen C., Broses, Luke J., Han, Amy L., Briggs, Hannah L., Emamdjomeh, Amir, Chou, Andrew, Abel, Ethan V., Liebert, Monica, Palmbos, Phillip L., Udager, Aaron M., Keller, Evan T., Day, Mark L.

“…The invasion of bladder cancer into the sub-urothelial muscle and vasculature are key determinants leading to lethal metastatic progression. However, the…”
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MP24-14 RADIATION THERAPY ATTENUATES REGENERATION OF THE UROTHELIUM IN NOVEL CELL CULTURE RADIATION MODEL by Zwaans, Bernadette, Bartolone, Sarah, Levanovich, Peter, Liebert, Monica, Chancellor, Michael, Lamb, Laura

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PD18-02 INCREASED URINARY VASCULAR ENDOTHELIAL GROWTH FACTOR D (VEGF-D) LEVELS ARE ASSOCIATED WITH RESPONSE TO COMBINED INTRAVESICAL BACILLUS CALMETTE−GUERIN (BCG) AND ORAL SUNITINIB REGIMEN FOR TREATMENT OF HIGH-RISK NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC) by Walker, Colton H., Lebastchi, Amir H., Russell, Christopher M., Daignault−Newton, Stephanie, Liebert, Monica, Hafez, Khaled S., Hussain, Maha H., Montgomery, Jeffrey S., Miller, David C., Hollenbeck, Brent K., Weizer, Alon Z., Kaffenberger, Samuel D.

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Autophagy inhibition (AI) as a novel treatment strategy in bladder cancer (BC) by Grivas, Petros, Visconte, Valeria, Day, Mark L., Day, Kathleen C., Liebert, Monica, Palmbos, Phillip Lee, Tomlins, Scott A., Carew, Jennifer

“…Abstract only 449 Background: BC response to chemotherapy has reached a plateau; novel treatment targets are needed. Autophagy is an important protein…”
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A Surgical Orthotopic Approach to Study the Invasive Progression of Human Bladder Cancer by Hiles, Guadalupe Lorenzatti, Cates, Angelica L., El-Sawy, Layla, Day, Kathleen C., Broses, Luke J., Han, Amy L., Briggs, Hannah L., Emamdjomeh, Amir, Chou, Andrew, Abel, Ethan V., Liebert, Monica, Palmbos, Phillip L., Udager, Aaron M., Keller, Evan T., Day, Mark L.

“…The invasion of bladder cancer into the sub-urothelial muscle and vasculature are key determinants leading to lethal metastatic progression. However, the…”
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Phase II clinical trial of intravesical bacillus Calmette-Guerin (BCG) followed by sunitinib for the treatment of high-risk nonmuscle-invasive bladder cancer (NMIBC) by Helfand, Alexander M., Lee, Cheryl T., Hafez, Khaled, Hussain, Maha, Liebert, Monica, Daignault, Stephanie, Montgomery, Jeffrey Scott, Miller, David Christopher, Drnek, Linda, Hollenbeck, Brent K., Weizer, Alon Z.

“…Abstract only 293 Background: We conducted a phase II trial to evaluate combination therapy with intravesical BCG + sunitinib for prevention of recurrence and…”
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Loss of 15-Hydroxyprostaglandin Dehydrogenase Expression Contributes to Bladder Cancer Progression by Tseng-Rogenski, Stephanie, Gee, Jason, Ignatoski, Kathleen Woods, Kunju, Lakshmi P, Bucheit, Amanda, Kintner, Hallie J, Morris, David, Tallman, Christopher, Evron, Joshua, Wood, Christopher G, Grossman, H. Barton, Lee, Cheryl T, Liebert, Monica

“…Prostaglandin E2, which is known to contribute to cancer progression, is inactivated by the catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase (PGDH),…”
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ATDC/TRIM29 drives invasive bladder cancer formation through microRNA-mediated and epigenetic mechanisms by Palmbos, Phillip L., Wang, Lidong, Yang, Huibin, Wang, Yin, Leflein, Jacob, Ahmet, McKenzie L., Wilkinson, John E., Kumar-Sinha, Chandan, Ney, Gina M., Tomlins, Scott A., Daignault, Stephanie, Kunju, Lakshmi. P., Wu, Xue-Ru, Lotan, Yair, Liebert, Monica, Ljungman, Mats E., Simeone, Diane M.

“…Bladder cancer is a common and deadly malignancy but its treatment has advanced little due to poor understanding of the factors and pathways that promote…”
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Abstract 313: ATDC drives bladder cancer formation by promoting methylation of the PTEN promoter and inhibition of p53 function by Palmbos, Phillip, Wang, Lidong, Yang, Huibin, Detzler, Taylor, Ney, Gina, Hart, Justin, Daignault-Newton, Stephanie, Kunju, L. Priya, Kumar-Sinha, Chandan, Liebert, Monica, Ljungman, Mats, Simeone, Diane

“…Abstract Bladder cancer is the 5th most common malignancy and a significant cause of morbidity and mortality, but the molecular events leading to its…”
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