Search Results - "Lieberman, J"

A Once Malignant Malady: the Story of Schizophrenia and the Path to Prevention by Lieberman, J.

“…Schizophrenia is synonymous in the public’s mind with madness. To see someone experiencing a florid psychosis, who has lost the ability to distinguish between…”
Get full text

Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents by Miyamoto, S, Miyake, N, Jarskog, L F, Fleischhacker, W W, Lieberman, J A

“…Since the introduction of chlorpromazine and throughout the development of the new-generation antipsychotic drugs (APDs) beginning with clozapine, the D 2…”
Get full text

Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention by Lieberman, J A, Girgis, R R, Brucato, G, Moore, H, Provenzano, F, Kegeles, L, Javitt, D, Kantrowitz, J, Wall, M M, Corcoran, C M, Schobel, S A, Small, S A

“…Scientists have long sought to characterize the pathophysiologic basis of schizophrenia and develop biomarkers that could identify the illness. Extensive…”
Get full text

Special delivery: targeted therapy with small RNAs by Peer, D, Lieberman, J

“…Harnessing RNA interference using small RNA-based drugs has great potential to develop drugs designed to knock down expression of any disease-causing gene,…”
Get full text

Roles for neuronal and glial autophagy in synaptic pruning during development by Lieberman, Ori J., McGuirt, Avery F., Tang, Guomei, Sulzer, David

“…The dendritic protrusions known as spines represent the primary postsynaptic location for excitatory synapses. Dendritic spines are critical for many synaptic…”
Get full text

Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs by MIYAMOTO, S, DUNCAN, G. E, MARX, C. E, LIEBERMAN, J. A

“…The treatment of schizophrenia has evolved over the past half century primarily in the context of antipsychotic drug development. Although there has been…”
Get full text

TIKL: Development of a Wearable Vibrotactile Feedback Suit for Improved Human Motor Learning by Lieberman, J.., Breazeal, C..

“…When humans learn a new motor skill from a teacher, they learn using multiple channels. They receive high level information aurally about the skill, visual…”
Get full text

Granzyme B-induced mitochondrial ROS are required for apoptosis by Jacquemin, G, Margiotta, D, Kasahara, A, Bassoy, E Y, Walch, M, Thiery, J, Lieberman, J, Martinvalet, D

“…Caspases and the cytotoxic lymphocyte protease granzyme B (GB) induce reactive oxygen species (ROS) formation, loss of transmembrane potential and…”
Get full text

Dietary therapy can reverse esophageal subepithelial fibrosis in patients with eosinophilic esophagitis: a historical cohort by Lieberman, J. A., Morotti, R. A., Konstantinou, G. N., Yershov, O., Chehade, M.

“…Background Fibrosis of the esophageal lamina propria is a known complication of eosinophilic esophagitis (EoE). To date, therapy with topical corticosteroids…”
Get full text

Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes—multicenter, double-blinded and randomized controlled trial by Worrilow, K.C., Eid, S., Woodhouse, D., Perloe, M., Smith, S., Witmyer, J., Ivani, K., Khoury, C., Ball, G.D., Elliot, T., Lieberman, J.

“…STUDY QUESTION Does the selection of sperm for ICSI based on their ability to bind to hyaluronan improve the clinical pregnancy rates (CPR) (primary…”
Get full text

Synaptic plasticity may underlie l-DOPA induced dyskinesia by Borgkvist, Anders, Lieberman, Ori J, Sulzer, David

“…•Denervation of dopamine neurons triggers changes in intrinsic excitability in striatal spiny projection neurons.•Dyskinesia can be elicited without prior…”
Get full text

Trends in the use of dual mobility bearings in hip arthroplasty: an analysis of the American Joint Replacement Registry by Weitzman, Dena S, Jaffri, Heena, Berry, Daniel J, Springer, Bryan D, Lieberman, J R

“…AimsDual mobility (DM) bearings are an attractive treatment option to obtain hip stability during challenging primary and revision total hip arthroplasty (THA)…”
Get full text

Reexamining cholinesterase inhibitors for the prevention and treatment of delirium in high-risk populations by Lieberman, Ori J, Douglas, Vanja C, LaHue, Sara C

“…AChEi’s, like donepezil and rivastigmine, provide symptomatic benefit in neurocognitive disorders by reducing the slope of cognitive decline and improving…”
Get full text

MODULAR APPROACH TO 3D REPRESENTATION OF UNDERGROUND INFRASTRUCTURE IN THE MODEL FOR UNDERGROUND DATA DEFINITION AND INTEGRATION (MUDDI) by Lieberman, J., Roensdorf, C.

“…Data and models of the built environment enable urban systems to serve their inhabitants and adapt to ever increasing rates of change in society, climate, and…”
Get full text

Can Interactions Between α-Synuclein, Dopamine and Calcium Explain Selective Neurodegeneration in Parkinson's Disease? by Post, Michael R, Lieberman, Ori J, Mosharov, Eugene V

“…Several lines of evidence place alpha-synuclein (aSyn) at the center of Parkinson's disease (PD) etiology, but it is still unclear why overexpression or…”
Get full text

Synaptophysin and postsynaptic density protein 95 in the human prefrontal cortex from mid-gestation into early adulthood by Glantz, L.A, Gilmore, J.H, Hamer, R.M, Lieberman, J.A, Jarskog, L.F

“…Abstract Previous studies of postnatal synaptic development in human frontal cortex have shown that synaptic density rises after birth, reaches a plateau in…”
Get full text

AOA Critical Issues Symposium: So, You Want to Be a Department Leader: Essentials for Success by Lieberman, J R, Boden, S D, Pellegrini, V D, Peabody, T D

“…Most health systems are vertically integrated, and the leaders of orthopaedic surgery departments or service lines must have a comprehensive understanding of…”
Get full text

Effects of proprioception and core stability training on gait parameters of deaf adolescents: a randomized controlled trial by Zarei, Hamed, Norasteh, Ali Asghar, Lieberman, Lauren J., Ertel, Michael W., Brian, Ali

“…The current study aimed to explore the effects of proprioception versus core stability training over 8 weeks on the gait parameters of deaf adolescents. A…”
Get full text

miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes by Perdigão-Henriques, R, Petrocca, F, Altschuler, G, Thomas, M P, Le, M T N, Tan, S M, Hide, W, Lieberman, J

“…The miR-200 family promotes the epithelial state by suppressing the Zeb1/Zeb2 epithelial gene transcriptional repressors. To identify other miR-200-regulated…”
Get full text

The silent treatment: siRNAs as small molecule drugs by Dykxhoorn, D M, Palliser, D, Lieberman, J

“…As soon as RNA interference (RNAi) was found to work in mammalian cells, research quickly focused on harnessing this powerful endogenous and specific mechanism…”
Get full text